Results 71 to 80 of about 3,007,514 (284)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
A review of the APC and CPD requirements of five built environment professional bodies [PDF]
Built environment higher education is significantly concerned with education for the professions. This is reflected in the substantial number of professionally accredited built environment degree courses and by the fact that degree course study underpins
Howarth, Tim
core
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Applying project management concepts and tools to built environment research projects [PDF]
This paper concerns the issue of Built Environment research students utilising a formal approach for designing and conducting research projects. The authors draw upon their experience of supervising and examining Built Environment research projects at ...
Howarth, Tim, Watson, Paul
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Kine-Mould: Flexible mould system opens up wide range of possibilities
The Kine-Mould is a development that makes it easier to manufacture building elements with complex geometry. Since June 2014 the team has been working on a range of solutions and prototypes.
Roel Schipper +14 more
doaj +3 more sources
A method for metropolitan landscape characterization; case study Rotterdam
This paper presents a theoretical and methodological framework for a comprehensive landscape characterization, focussing on the largest and most complex urban realm: the metropolitan region.
Alexandra Tisma +3 more
doaj +1 more source
Role of built environment education curricula in post- disaster recovery management [PDF]
This paper explains the rationale behind the European Commission funded EURASIA research project, emphasising the importance of the role of built and human education curricular in post-disaster recovery management.
Amaratunga, Dilanthi +2 more
core
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

