Results 71 to 80 of about 7,754,384 (286)

Product Development Lab (PD Test Lab)

Spool, 2018
The file to factory approach is investigated within the Product Development Test Lab, with the first entirely digitally produced building as a demonstrator and test lab on the campus of TU Delft.
Pieter Stoutjesdijk, Tillmann Klein, Marcel Bilow, Jos Lichtenberg, Jeroen van Veen, Nick van der Knaap   +5 more
doaj   +5 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Analysing the Environmental and Social Impacts of a Novel User-Based Transit Signal Priority Strategy in a Connected Vehicle Environment

Journal of Advanced Transportation
Transit signal priority (TSP) is a traffic control strategy aiming at prioritising public transit vehicles at signalised intersections. The emergence of connected vehicles (CVs) provides the opportunity to enhance TSP operation, mitigating challenges ...
Roozbeh Mohammadi, Shaghayegh Vosough, Claudio Roncoli   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Place-Making or Place-Taking? Transformation of Danish Disadvantaged Housing Estates

Nordic Journal of Urban Studies
Several Danish social housing estates are currently being transformed according to the Parallel Society Act. This legislation has introduced what is, in a Danish context, a new approach to regeneration, involving tenure mix, evictions, and targeted ...
Marie Stender, Lene Wiell Nordberg, Rikke Skovgaard Nielsen, Mette Mechlenborg, Claus Bech-Danielsen   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Built environment research in West Africa current trends and future directions [PDF]

, 2011
The countries in West Africa (WA) are pushing for socio-economic development. The construction sector has an important part to play in helping to realise these aspirations.
Leiringer, R, Laryea, Sam, Leiringer, Roine Tonny Fredrik, Laryea, S   +3 more
core  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

BSS401: Environmental Science and Services I / College of Built Environment [PDF]

, 2015
The subject focused on (i) Environmental Sciences: Climatic influence on living comfort and the built environment.
UiTM, College of Built Environment
core  

Tools of the Architect

Spool, 2018
What tools, procedures, and methods do architects use? The triptychs on display show their approach both in analytical and designerly ways. The first panel of each triptych represents an architectural question; the second panel represents a method.
Willemijns Wilms Floet, Klaske Havik, Tom Avermaete, Jorge Meíja Hernández   +3 more
doaj   +3 more sources