Results 111 to 120 of about 371,889 (314)

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

open access: yesAdvanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu   +14 more
wiley   +1 more source

Studies of specific nuclear light bulb and open-cycle vortex stabilized gaseous nuclear rocket engines [PDF]

open access: yes
Specific nuclear light bulb and open-cycle vortex stabilized gaseous nuclear rocket engine ...
Bauer, H. E., Mc Lafferty, G. H.
core   +1 more source

Smart materials application on high performance sailing yachts for energy harvesting [PDF]

open access: yes, 2013
Piezoelectric patches are bounded on a keel bulb in order to harvest vibration energy by converting electrical output. Unsteady computational fluid dynamics method is also used to find the structural boundary condition such as the hydrodynamic pressure ...
Khorasanchi, Mahdi   +2 more
core  

Olfactory‐to‐Entorhinal Network Dysrhythmias Drive Parkinson's Cognitive Impairment Through Frequency‐Specific Oscillatory Decoupling

open access: yesAdvanced Science, EarlyView.
Wang et al reveal that in the olfactory system, the selective impairment of gamma‐driven Barcode features underlying early olfactory deficits, while the selective impairment of theta‐driven Barcode features underlying later cognitive deficits, further establishing cross‐network gamma oscillations in the early stage as a biomarker of later cognitive ...
Shuaishuai Wang   +13 more
wiley   +1 more source

Hydrogen maser for field use Technical report, Jun. 27, 1966 - Jan. 30, 1968 [PDF]

open access: yes
Hydrogen maser for field use with cavity and bulb design of maser for satellite ...
Mueller, L., Vessot, R.
core   +1 more source

Multimodal Optical Imaging and Modulation with Simultaneous Electrophysiology Through Smart Dura in Non‐Human Primates

open access: yesAdvanced Science, EarlyView.
This study demonstrates multimodal integration in non‐human primates, combining large‐scale, high‐density electrophysiology using Smart Dura with optical techniques such as multiphoton imaging (MPI), photothrombotic lesioning, optical coherence tomography angiography (OCTA), wide‐field intrinsic signal optical imaging (ISOI), and optogenetics.
Nari Hong   +10 more
wiley   +1 more source

Analysis of the operating conditions of a hydraulic turbine of the bulb-type

open access: diamond, 2021
Adriano Delmaschio Cella   +2 more
openalex   +2 more sources

Brd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway

open access: yesAdvanced Science, EarlyView.
MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li   +10 more
wiley   +1 more source

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