Results 41 to 50 of about 410,227 (240)

A fourfold coordinated point defect in silicon

, 2002
Due to their technological importance, point defects in silicon are among the best studied physical systems. The experimental examination of point defects buried in bulk is difficult and evidence for the various defects usually indirect.
A. Antonelli, F. Cargoni, F. Wooten, G. Bachelet, G. Baraff, G. Watkins, J. Doye, J. Perdew, K. Pandey, Luc Billard, M. Payne, M. Puska, N. Marzari, P. Blöchl, P. Pulay, R. Car, R. Needs, S. Clark, S. Goedecker, Stefan Goedecker, T. Lenosky, Thierry Deutsch, W. Lee, W. Leung, Y. Bar-Yam   +24 more
core   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Room-temperature ferromagnetism in graphite driven by 2D networks of point defects

, 2009
Ferromagnetism in carbon-based materials is appealing for both applications and fundamental science purposes because carbon is a light and bio-compatible material that contains only s and p electrons in contrast to traditional ferromagnets based on 3d or
AA Ovchinnikov, AV Rode, AW Mombrú, C. F. J. Flipse, F Pedreschi, G Wagoner, H Kumazaki, H Ohldag, J Červenka, J Červenka, J. Červenka, JMD Coey, M Fujita, M. I. Katsnelson, MAH Vozmediano, N Park, NMR Peres, OV Yazyev, OV Yazyev, OV Yazyev, P Esquinazi, P Esquinazi, P Esquinazi, PO Lehtinen, R Allenspach, R Faccio, S Talapatra, T Kebe, TO Wehling, VY Irkhin, Y Kobayashi, Y Kobayashi, Y Kopelevich, Y Lu, Y Niimi, Y Niimi, Y-W Son   +36 more
core   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Self-organized dynamics and the transition to turbulence of confined active nematics

, 2019
We study how confinement transforms the chaotic dynamics of bulk microtubule-based active nematics into regular spatiotemporal patterns. For weak confinements, multiple continuously nucleating and annihilating topological defects self-organize into ...
Aghvami, S. Ali, Dogic, Zvonimir, Fraden, Seth, Juniper, Michael P. N., Langeslay, Blake, Norton, Michael M., Opathalage, Achini   +6 more
core   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Line Defects in Molybdenum Disulfide Layers

, 2013
Layered molecular materials and especially MoS2 are already accepted as promising candidates for nanoelectronics. In contrast to the bulk material, the observed electron mobility in single-layer MoS2 is unexpectedly low.
Albu-Yaron A., Andrey N. Enyashin, Bar-Sadan M., Bar-Sadan M., Bollinger M. V., Coleman J. N., Enyashin A. N., Enyashin A. N., Enyashin A. N., Fivaz R., Gotthard Seifert, Houben L., Jia C. L., Kam K. K., Kaplan-Ashiri I., Kim D., Komsa H. P., Lauritsen J. V., Lee Y. H., Lentzen M., Liu K. K., Lothar Houben, Matte H. S. S. R., Maya Bar-Sadan, Najmaei S., Novoselov K. S., Novoselov K. S., Ostwald W., Podzorov V., Radisavljevic B., Seifert G., Seifert G., Shiojiri M., Stadelmann P. A., van der Zande A. M., Wilson J. A., Zhan Y. J., Zou X. L.   +37 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source