Results 41 to 50 of about 1,387,503 (298)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Coupled surface and bulk diffusion in crystals

open access: yesAIP Advances, 2022
We analyze point defect bulk and surface diffusion near the crystal–vacuum interface and show that bulk diffusion is coupled with surface diffusion via the atomic processes in the intermediate subsurface layer.
S. S. Kosolobov
doaj   +1 more source

Perturbative bootstrap of the Wilson-line defect CFT: Bulk-defect-defect correlators

open access: yesJournal of High Energy Physics
A bstract We study the correlators of bulk and defect half-BPS operators in $$ \mathcal{N} $$ N
Daniele Artico   +2 more
openaire   +5 more sources

On the scattering of torsional elastic waves from axisymmetric defects in coated pipes [PDF]

open access: yes, 2012
This is the post-print version of the Article - Copyright @ 2012 ElsevierLong range ultrasonic testing is now a well established method for examining in-service degradation in pipelines.
Mudge, P, Zlatev, Z, Kirby, R
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Low-Defect Bulk-Germanium-on-Insulator Photodetectors with Resonant Cavity Enhancement at 1550 nm for High-Resolution SWIR Imaging

open access: yesNanomaterials
High-resolution short-wave infrared (SWIR) imaging requires photodetectors (PDs) with simultaneously low dark current and high responsivity. To achieve this goal, we demonstrate low-defect bulk germanium-on-insulator (bulk-GeOI) PDs designed for enhanced
Jiale Su   +10 more
doaj   +1 more source

Delamination Detection in Bimetallic Composite Using Laser Ultrasonic Bulk Waves

open access: yesApplied Sciences, 2021
In this study, a method based on laser ultrasonic bulk waves is used to detect delamination in a bimetallic composite. For this purpose, several artificial delamination defects were created in a copper-aluminum sample using wire-electrode cutting.
Baoping Ji   +4 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Fusion of conformal defects in four dimensions

open access: yesJournal of High Energy Physics, 2021
We consider two conformal defects close to each other in a free theory, and study what happens as the distance between them goes to zero. This limit is the same as zooming out, and the two defects have fused to another defect. As we zoom in we find a non-
Alexander Söderberg
doaj   +1 more source

materialsproject/pymatgen-analysis-defects: v2022.11.30

open access: yes, 2022
What's Changed Defect transition CCD by @jmmshn in https://github.com/materialsproject/pymatgen-analysis-defects/pull/33 fix repository url by @njzjz in https://github.com/materialsproject/pymatgen-analysis-defects/pull/35 fixed test by @jmmshn in https:
nwinner   +3 more
core   +1 more source

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