An infant with bullous pemphigoid
Bullous pemphigoid is the most common subepidermal autoimmune blistering disease. However, it is very rare in the pediatric population. A 5-month-old male infant presented with multiple bullae located on palms and soles. Complete blood count revealed relative eosinophilia .
Santos, António Luís+4 more
openaire +5 more sources
Bullous pemphigoid in infants: characteristics, diagnosis and treatment [PDF]
BACKGROUND: Bullous pemphigoid (BP) in infants is a rare but increasingly reported autoimmune blistering skin disease. Autoantibody reactivity is usually poorly characterized. Current guidelines do not address specific aspects of the infantile form of BP.
Agnes Schwieger-Briel+8 more
core +2 more sources
Lower Extremity Salvage in the Setting of Bullous Pemphigoid Exacerbation: A Case Report
Summary:. Bullous pemphigoid is an autoimmune blistering disease where patients suffer from painful bullae, often covering large portions of the skin and requiring management with immune-suppression.
Samara E. Pollock, MD+5 more
doaj +1 more source
Bullous pemphigoid and autoimmunity
There are many case reports of bullous pemphigoid (BP) in association with a variety of autoimmune disorders, but no large case controlled studies have been performed.Our purpose was to determine whether there is an increased incidence of autoimmune disorders in patients with BP and whether there is a particular haplotype associated with this.A total ...
Taylor, G+3 more
openaire +4 more sources
The Syk tyrosine kinase is required for skin inflammation in an in vivo mouse model of epidermolysis bullosa acquisita [PDF]
The inflammatory form of epidermolysis bullosa acquisita is caused by autoantibodies against type VII collagen (C7), a component of the dermal-epidermal junction.
Mócsai, Attila+3 more
core +1 more source
The Complex Role of IL‐13 in Bullous Pemphigoid: New Insights From a Retrospective Cohort Study
ABSTRACT Background Bullous pemphigoid (BP) is the most common autoimmune blistering skin disease, primarily affecting the elderly. The role of interleukin‐13 (IL‐13) in BP pathogenesis remains unclear, particularly regarding its potential as a therapeutic target.
Marwan Dawood+6 more
wiley +1 more source
Dupilumab for bullous pemphigoid with intractable pruritus [PDF]
Bullous pemphigoid (BP) is an autoimmune blistering disorder that predominantly affects the elderly. Treatment regimens typically include topical and systemic immunosuppressive medications.
Eichenfield, Dawn Z+2 more
core
A case report of bullous pemphigoid following secukinumab therapy for a patient with psoriasis
Aim: Bullous pemphigoid induced by secukinumab in treatment of psoriasis is rare.Methods: We report a 49-year-old man with psoriasis who developed bullous pemphigoid during treatment with secukinumab.Results: Scattered tense vesicles with itching ...
Guanghan Wang+3 more
doaj +1 more source
Clinical Relevance of Autoantibodies in Patients with Autoimmune Bullous Dermatosis
The authors present their experience related to the diagnosis, treatment, and followup of 431 patients with bullous pemphigoid, 14 patients with juvenile bullous pemphigoid, and 273 patients with pemphigus.
Lilla Mihályi+4 more
doaj +1 more source
Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin [PDF]
The cornified envelope is a layer of transglutaminase cross-linked protein that is assembled under the plasma membrane of keratinocytes in the outermost layers of the epidermis.
Argos+57 more
core +2 more sources