Results 91 to 100 of about 342,393 (334)
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
A Tannakian interpretation of the elliptic infinitesimal braid Lie algebras
, 2017 Let $n\geq 1$. The pro-unipotent completion of the pure braid group of $n$ points on a genus 1 surface has been shown to be isomorphic to an explicit pro-unipotent group with graded Lie algebra using two types of tools: (a) minimal models (Bezrukavnikov),
Enriquez, Benjamin, Etingof, Pavel
core +2 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Polarized Spinoptics and Symplectic Physics
, 2013 We recall the groundwork of spinoptics based on the coadjoint orbits, of given color and spin, of the group of isometries of Euclidean three-space; this model has originally been put forward by Souriau in his treatise "Structure des Syst\'emes Dynamiques"
Duval, Christian
core +1 more source
Positivity conditions for Hermitian symmetric functions
, 2003 We introduce a countable collection of positivity classes for Hermitian symmetric functions on a complex manifold, and establish their basic properties. We study a related notion of stability. The first main result shows that, if the underlying matrix of
D'Angelo, John P., Varolin, Dror
core +2 more sources
FEBS Letters, EarlyView.C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source
Revista Colombiana de Cardiología, 2010 Se conoce que la estimulación en el ápex del ventrículo derecho produce disincronía ventricular y muchas veces los pacientes desarrollan miocardiopatía dilatada, lo que ha llevado a realizar una estimulación más fisiológica.
Jorge E Velásquez +7 more
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