Results 181 to 190 of about 342,393 (334)

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

Left bundle branch pacing in patients with structural heart disease: personalizing cardiac resynchronization therapy. [PDF]

open access: yesEuropace
Joza J   +6 more
europepmc   +1 more source

Recordings of His Bundle and Other Conduction Potentials in Children [PDF]

open access: bronze, 1970
Sidney J. Brodsky   +4 more
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Physiological pacing: mechanisms, clinical indications, and perspectives. [PDF]

open access: yesEur Heart J
Whinnett Z   +4 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy