Results 21 to 30 of about 7,708 (163)
Activation of PKR by Bunyamwera virus is independent of the viral interferon antagonist NSs [PDF]
Double-stranded RNA (dsRNA) is a by-product of viral RNA polymerase activity, and its recognition is one mechanism by which the innate immune system is activated.
Boyd, A. +25 more
core +1 more source
Functional analysis of the Bunyamwera orthobunyavirus Gc glycoprotein [PDF]
The virion glycoproteins Gn and Gc of Bunyamwera orthobunyavirus (BUNV, family Bunyaviridae) are encoded by the M RNA genome segment and have roles in both viral attachment and membrane fusion.
Elliott, Richard Michael +9 more
core +1 more source
Establishment of a reverse genetics system for Schmallenberg virus, a newly emerged orthobunyavirus in Europe [PDF]
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus that has caused widespread disease in cattle, sheep and goats in Europe. Like other orthobunyaviruses, SBV is characterized by a tripartite negative-sense RNA genome that encodes four ...
Szemiel, A.M. +15 more
core +1 more source
Bunyamwera bunyavirus nonstructural protein NSs counteracts the induction of alpha/beta interferon [PDF]
Production of alpha/beta interferons (IFN-α/β) in response to viral infection is one of the main defense mechanisms of the innate immune system. Many viruses therefore encode factors that subvert the IFN system to enhance their virulence.
Richard E. Randall +29 more
core +1 more source
Early Bunyavirus-Host Cell Interactions
The Bunyaviridae is the largest family of RNA viruses, with over 350 members worldwide. Several of these viruses cause severe diseases in livestock and humans.
Amelina Albornoz +3 more
doaj +1 more source
Saurashtra region is highly affected by presence of highly contagious zoonotic disease. Crimean-Congo Hemorrhagic Fever is cause by tick borne virus belonging Bunyaviridae family. Eleven confirm cases of CCHF were identified in Bhavnagar District during
Bansi J Trivedi, Atul V Trivedi
doaj +1 more source
The small genome segment of Bunyamwera orthobunyavirus harbours a single transcription-termination signal [PDF]
Transcription termination of the mRNA produced from the small (S) genome segment of Bunyamwera orthobunyavirus (BUNV) has previously been mapped to two cis-acting sequences located within the 5′ UTR using a virus-free replication assay.
Elliott, Richard Michael +5 more
core +1 more source
Molecular characterization of Umbre virus (Bunyaviridae)
Umbre (UMB) virus was first isolated from India in 1955 and classified as Orthobunyavirus (Turlock serogroup). Eight isolates of this virus, isolated from Culex mosquitoes were characterized on the basis of partial glycoprotein (G2) gene.
Mourya Devendra T +2 more
doaj +1 more source
The role of platelets in the pathogenesis of viral hemorrhagic fevers. [PDF]
Viral hemorrhagic fevers (VHF) are acute zoonotic diseases that, early on, seem to cause platelet destruction or dysfunction. Here we present the four major ways viruses affect platelet development and function and new evidence of molecular factors that ...
Juan C Zapata +2 more
doaj +1 more source
ABSTRACT Background Crimean–Congo hemorrhagic fever (CCHF) remains a significant zoonotic and public health threat in endemic regions, including Iraq, which has experienced repeated outbreaks over the past decade. Recent surveillance data suggest evolving transmission dynamics influenced by climatic variability, ecological conditions, and the intensity
Sirwan Sleman +4 more
wiley +1 more source

