Genomic Characterization of the Genus Nairovirus (Family Bunyaviridae) [PDF]
Viruses, 2016 Nairovirus, one of five bunyaviral genera, includes seven species. Genomic sequence information is limited for members of the Dera Ghazi Khan, Hughes, Qalyub, Sakhalin, and Thiafora nairovirus species.
Gustavo Palacios +2 more
exaly +6 more sources
Identification of cellular ion channels that facilitate Hazara nairovirus infection enables selection of clinically approved compounds with anti-nairoviral properties [PDF]
Scientific ReportsThe Nairoviridae family of segmented negative-sense RNA viruses includes the serious human pathogen Crimean-Congo haemorrhagic fever virus (CCHFV), associated with a case/fatality rate of up to 40% for which no approved vaccines or treatments exist ...
Frank W. Charlton +8 more
doaj +2 more sources
Bioinformatic Surveillance Leads to Discovery of Two Novel Putative Bunyaviruses Associated with Black Soldier Fly [PDF]
Viruses, 2023 The black soldier fly (Hermetia illucens, BSF) has emerged as an industrial insect of high promise because of its ability to convert organic waste into nutritious feedstock, making it an environmentally sustainable alternative protein source.
Hunter K. Walt +6 more
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Pathogenesis of Hazara orthonairovirus infection in type I interferon receptor-deficient mice and resolution of disease following 4′-fluorouridine therapy [PDF]
Journal of VirologyThe Crimean-Congo hemorrhagic fever orthonairovirus (CCHFV) is a widespread tick-borne agent that causes severe disease in humans. Its expanding geographic range poses a significant public health threat.
Justin S. Murray +8 more
doaj +2 more sources
Rapid and visual detection of Tacheng tick virus 1 using loop-mediated isothermal amplification technique [PDF]
Frontiers in Cellular and Infection MicrobiologyIntroductionTacheng tick virus 1 (TcTV-1) is an emerging tick-borne nairovirus associated with human febrile illness. To date, no reliable detection method for TcTV-1 has been established.
Qiqi Guo +7 more
doaj +2 more sources
Targeted cleavage site mutations in the Gn precursor enable efficient generation of replication-competent rVSV-based surrogates for emerging nairoviruses [PDF]
Emerging Microbes and InfectionsOrthonairoviruses are rapidly emerging, tick-borne viruses including Crimean Congo hemorrhagic fever virus (CCHFV), a highly pathogenic virus requiring biosafety level 4 (BSL-4) containment.
Shilpi Jain +10 more
doaj +2 more sources
Crimean-Congo hemorrhagic fever with severe bradycardia treated with Theophylline [PDF]
Revista da Sociedade Brasileira de Medicina TropicalCrimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral hemorrhagic fever caused by Nairovirus and characterized by fever, myalgia, arthralgia, and hemorrhagic manifestations. Severe bradycardia is a rare complication of the disease. We present a 30-
Murat Aydın, Nurten Nur Aydın
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Striking tick-borne virus diversity and potential reservoirs documented during One-Health-based cross-sectional screening in Anatolia [PDF]
Parasites & VectorsBackground An expansion of recently described human pathogenic tick-borne viruses from Central Asia toward Europe has been documented. Located on important bird migration routes, Anatolia is an intercontinental crossing hub with various climactic zones ...
Ender Dinçer +14 more
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Metatranscriptomic analysis reveals the diversity of RNA viruses in ticks in Inner Mongolia, China. [PDF]
PLoS Neglected Tropical DiseasesBackgroundTicks are widely distributed throughout China and are the second most prevalent pathogen vectors in the world, following only mosquitoes. Tick bites can lead to Lyme disease, forest encephalitis, and other illnesses that may result in death ...
Si Su +10 more
doaj +2 more sources
Metagenomic Nanopore Sequencing of Tickborne Pathogens, Mongolia [PDF]
Emerging Infectious DiseasesWe performed nanopore-based metagenomic screening on 885 ticks collected from 6 locations in Mongolia and divided the results into 68 samples: 23 individual samples and 45 pools of 2–12 tick samples each.
Koray Ergunay +11 more
doaj +2 more sources