Results 21 to 30 of about 1,414 (150)

The Input of Structural Vaccinology in the Search for Vaccines against Bunyaviruses

Viruses, 2021
A significant increase in the number of viruses causing unexpected illnesses and epidemics among humans, wildlife and livestock has been observed in recent years.
Alexandra Serris
doaj   +1 more source

A new nairo-like virus associated with human febrile illness in China

Emerging Microbes and Infections, 2021
Several nairo-like viruses have been discovered in ticks in recent years, but their relevance to public health remains unknown. Here, we found a patient who had a history of tick bite and suffered from a febrile illness was infected with a previously ...
Yan-Chun Wang, Zhengkai Wei, Xiaolong Lv, Shuzheng Han, Zedong Wang, Changfa Fan, Xu Zhang, Jianwei Shao, Ying-Hua Zhao, Liyan Sui, Chen Chen, Ming Liao, Bo Wang, Ningyi Jin, Chang Li, Jun Ma, Zhi-Jun Hou, Zhengtao Yang, Zhen Han, Yong Zhang, Junqi Niu, Wei Wang, Youchun Wang, Quan Liu   +23 more
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Deubiquitylating Enzymes in Cancer and Immunity

Advanced Science, Volume 10, Issue 36, December 27, 2023., 2023
This review presents the fundamental understanding of deubiquitinating enzymes (DUBs) and then outlines the mechanisms and multi‐role of DUBs in determining the occurrence and development of tumor and immune disorders. DUBs in the crosstalk between cancer and immune response is then presented.
Jiang Ren, Peng Yu, Sijia Liu, Ran Li, Xin Niu, Yan Chen, Zhenyu Zhang, Fangfang Zhou, Long Zhang   +8 more
wiley   +1 more source

Structural and Functional Diversity of Nairovirus-Encoded Nucleoproteins [PDF]

Journal of Virology, 2015
ABSTRACT The nairoviruses include assorted tick-borne bunyaviruses that are emerging as causative agents of infectious diseases among humans and animals. As negative-sense single-stranded RNA (−ssRNA) viruses, nairoviruses encode nucleoprotein (NP) that encapsidates the genomic RNA and further forms ribonucleoprotein (RNP) complex with viral ...
Wenming, Wang, Xiang, Liu, Xu, Wang, Hui, Dong, Chao, Ma, Jingmin, Wang, Baocheng, Liu, Yonghong, Mao, Ying, Wang, Ting, Li, Cheng, Yang, Yu, Guo   +11 more
openaire   +2 more sources

Crimean‐Congo hemorrhagic fever outbreak in Pakistan, 2022: A warning bell amidst unprecedented floods and COVID 19 pandemic

Health Science Reports, Volume 6, Issue 1, January 2023., 2023
Abstract Crimean‐Congo hemorrhagic fever (CCHF) is an infection caused by a tick‐borne virus (genus: Nairovirus, family: Bunyaviridae). The most important vector for CCHF is the ixodid tick. Along with tick bite, direct contact with the virus‐affected animal is responsible for its spread. Pakistan witnessed its first case of CCHF in 1976 and has been a
Shehroze Tabassum, Aroma Naeem, Maleeka Zamurad Khan, Nimra Mumtaz, Saima Gill, Laya Ohadi   +5 more
wiley   +1 more source

The Geographical Coexist of the Migratory Birds, Ticks, and Nairobi Sheep Disease Virus May Potentially Contribute to the Passive Spreading of Nairobi Sheep Disease

Transboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
Nairobi sheep disease (NSD) is a hemorrhagic vector‐borne disease of small ruminants caused by the Nairobi sheep disease virus (NSDV), also known as Ganjam virus (GV). NSDV and GV refer to the same virus. The NSDV has been identified in East Africa, India, Sri Lanka, and China, and NSDV vector ticks can be carried by birds. There is few research on the
KwangHyok Kim, HaoNing Wang, JinMyong Cha, XiaoLong Wang, Fedor Korennoy   +4 more
wiley   +1 more source

Lack of Evidence for Crimean–Congo Hemorrhagic Fever Virus in Ticks Collected from Animals, Corsica, France

Emerging Infectious Diseases, 2022
In Corsica, France, 9.1% of livestock serum samples collected during 2014–2016 were found to have antibodies against Crimean–Congo hemorrhagic fever virus (CCHFV), an emerging tickborne zoonotic disease.
Vincent Cicculli, Apolline Maitre, Nazli Ayhan, Stevan Mondoloni, Jean-Christophe Paoli, Laurence Vial, Xavier N. de Lamballerie, Remi Charrel, Alessandra Falchi   +8 more
doaj   +1 more source

Diversity of Viruses in Ixodes ricinus in Europe including Novel and Potential Arboviruses

Transboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
Tick‐borne pathogens are responsible for many vector‐borne diseases in Europe, causing important problems for human and animal health. The composition of viral communities in ticks and their interactions with pathogens is little understood, especially in Eastern Europe, an area that represents a major hub for animal‐arthropod vectors exchanges. In this
Bianca Elena Bratuleanu, Cristian Răileanu, Amal Bennouna, Delphine Chretien, Thomas Bigot, Pablo Guardado-Calvo, Gheorghe Savuta, Sara Moutailler, Marc Eloit, Sarah Temmam, Abdelmalik Ibrahim Khalafalla   +10 more
wiley   +1 more source

From functional genomics of vero cells to CRISPR‐based genomic deletion for improved viral production rates

Biotechnology and Bioengineering, Volume 119, Issue 10, Page 2794-2805, October 2022., 2022
By further decoding the mechanisms at play during virus growth inside Vero cells, Sene et al. were able to increase the cells' viral yield by first detecting among the identified genes, via functional genomics, those that hinder the virus reproduction cycle (i.e., antiviral genes).
Marie‐Angélique Sène, Yu Xia, Amine A. Kamen   +2 more
wiley   +1 more source

Mapping of Antibody Epitopes on the Crimean-Congo Hemorrhagic Fever Virus Nucleoprotein

Viruses, 2022
Crimean-Congo hemorrhagic fever virus (CCHFV), a nairovirus, is a tick-borne zoonotic virus that causes hemorrhagic fever in humans. The CCHFV nucleoprotein (NP) is the antigen most used for serological screening of CCHFV infection in animals and humans.
Boniface Pongombo Lombe, Takeshi Saito, Hiroko Miyamoto, Akina Mori-Kajihara, Masahiro Kajihara, Masayuki Saijo, Justin Masumu, Takanari Hattori, Manabu Igarashi, Ayato Takada   +9 more
doaj   +1 more source