Results 21 to 30 of about 2,497 (196)

The Input of Structural Vaccinology in the Search for Vaccines against Bunyaviruses

open access: yesViruses, 2021
A significant increase in the number of viruses causing unexpected illnesses and epidemics among humans, wildlife and livestock has been observed in recent years.
Alexandra Serris
doaj   +1 more source

Exploring the Potential of Iminosugars as Antivirals for Crimean-Congo Haemorrhagic Fever Virus, Using the Surrogate Hazara Virus: Liquid-Chromatography-Based Mapping of Viral N-Glycosylation and In Vitro Antiviral Assays

open access: yesPathogens, 2023
Crimean-Congo haemorrhagic fever virus (CCHFV) is a pathogen of increasing public health concern, being a widely distributed arbovirus and the causative agent of the potentially fatal Crimean-Congo haemorrhagic fever. Hazara virus (HAZV) is a genetically
Beatrice E. Tyrrell   +11 more
doaj   +1 more source

Identification of critical residues for RNA binding of nairovirus nucleoprotein. [PDF]

open access: yesJ Virol
ABSTRACT Orthonairovirus haemorrhagiae (CCHFV) is a tick-borne virus of the Orthonairovirus genus. CCHFV nucleoprotein binds to the viral genomic RNA, which is essential for transcription and replication.
Ohta K, Saka N, Nishio M.
europepmc   +3 more sources

A new nairo-like virus associated with human febrile illness in China

open access: yesEmerging Microbes and Infections, 2021
Several nairo-like viruses have been discovered in ticks in recent years, but their relevance to public health remains unknown. Here, we found a patient who had a history of tick bite and suffered from a febrile illness was infected with a previously ...
Yan-Chun Wang   +23 more
doaj   +1 more source

Structural and Functional Diversity of Nairovirus-Encoded Nucleoproteins [PDF]

open access: yesJournal of Virology, 2015
ABSTRACT The nairoviruses include assorted tick-borne bunyaviruses that are emerging as causative agents of infectious diseases among humans and animals. As negative-sense single-stranded RNA (−ssRNA) viruses, nairoviruses encode nucleoprotein (NP) that encapsidates the genomic RNA and further forms ribonucleoprotein (RNP) complex with viral ...
Wenming, Wang   +11 more
openaire   +2 more sources

Deubiquitylating Enzymes in Cancer and Immunity

open access: yesAdvanced Science, Volume 10, Issue 36, December 27, 2023., 2023
This review presents the fundamental understanding of deubiquitinating enzymes (DUBs) and then outlines the mechanisms and multi‐role of DUBs in determining the occurrence and development of tumor and immune disorders. DUBs in the crosstalk between cancer and immune response is then presented.
Jiang Ren   +8 more
wiley   +1 more source

Lack of Evidence for Crimean–Congo Hemorrhagic Fever Virus in Ticks Collected from Animals, Corsica, France

open access: yesEmerging Infectious Diseases, 2022
In Corsica, France, 9.1% of livestock serum samples collected during 2014–2016 were found to have antibodies against Crimean–Congo hemorrhagic fever virus (CCHFV), an emerging tickborne zoonotic disease.
Vincent Cicculli   +8 more
doaj   +1 more source

Crimean‐Congo hemorrhagic fever outbreak in Pakistan, 2022: A warning bell amidst unprecedented floods and COVID 19 pandemic

open access: yesHealth Science Reports, Volume 6, Issue 1, January 2023., 2023
Abstract Crimean‐Congo hemorrhagic fever (CCHF) is an infection caused by a tick‐borne virus (genus: Nairovirus, family: Bunyaviridae). The most important vector for CCHF is the ixodid tick. Along with tick bite, direct contact with the virus‐affected animal is responsible for its spread. Pakistan witnessed its first case of CCHF in 1976 and has been a
Shehroze Tabassum   +5 more
wiley   +1 more source

The Geographical Coexist of the Migratory Birds, Ticks, and Nairobi Sheep Disease Virus May Potentially Contribute to the Passive Spreading of Nairobi Sheep Disease

open access: yesTransboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
Nairobi sheep disease (NSD) is a hemorrhagic vector‐borne disease of small ruminants caused by the Nairobi sheep disease virus (NSDV), also known as Ganjam virus (GV). NSDV and GV refer to the same virus. The NSDV has been identified in East Africa, India, Sri Lanka, and China, and NSDV vector ticks can be carried by birds. There is few research on the
KwangHyok Kim   +4 more
wiley   +1 more source

Mapping of Antibody Epitopes on the Crimean-Congo Hemorrhagic Fever Virus Nucleoprotein

open access: yesViruses, 2022
Crimean-Congo hemorrhagic fever virus (CCHFV), a nairovirus, is a tick-borne zoonotic virus that causes hemorrhagic fever in humans. The CCHFV nucleoprotein (NP) is the antigen most used for serological screening of CCHFV infection in animals and humans.
Boniface Pongombo Lombe   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy