Results 21 to 30 of about 2,497 (196)
The Input of Structural Vaccinology in the Search for Vaccines against Bunyaviruses
A significant increase in the number of viruses causing unexpected illnesses and epidemics among humans, wildlife and livestock has been observed in recent years.
Alexandra Serris
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Crimean-Congo haemorrhagic fever virus (CCHFV) is a pathogen of increasing public health concern, being a widely distributed arbovirus and the causative agent of the potentially fatal Crimean-Congo haemorrhagic fever. Hazara virus (HAZV) is a genetically
Beatrice E. Tyrrell +11 more
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Identification of critical residues for RNA binding of nairovirus nucleoprotein. [PDF]
ABSTRACT Orthonairovirus haemorrhagiae (CCHFV) is a tick-borne virus of the Orthonairovirus genus. CCHFV nucleoprotein binds to the viral genomic RNA, which is essential for transcription and replication.
Ohta K, Saka N, Nishio M.
europepmc +3 more sources
A new nairo-like virus associated with human febrile illness in China
Several nairo-like viruses have been discovered in ticks in recent years, but their relevance to public health remains unknown. Here, we found a patient who had a history of tick bite and suffered from a febrile illness was infected with a previously ...
Yan-Chun Wang +23 more
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Structural and Functional Diversity of Nairovirus-Encoded Nucleoproteins [PDF]
ABSTRACT The nairoviruses include assorted tick-borne bunyaviruses that are emerging as causative agents of infectious diseases among humans and animals. As negative-sense single-stranded RNA (−ssRNA) viruses, nairoviruses encode nucleoprotein (NP) that encapsidates the genomic RNA and further forms ribonucleoprotein (RNP) complex with viral ...
Wenming, Wang +11 more
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Deubiquitylating Enzymes in Cancer and Immunity
This review presents the fundamental understanding of deubiquitinating enzymes (DUBs) and then outlines the mechanisms and multi‐role of DUBs in determining the occurrence and development of tumor and immune disorders. DUBs in the crosstalk between cancer and immune response is then presented.
Jiang Ren +8 more
wiley +1 more source
In Corsica, France, 9.1% of livestock serum samples collected during 2014–2016 were found to have antibodies against Crimean–Congo hemorrhagic fever virus (CCHFV), an emerging tickborne zoonotic disease.
Vincent Cicculli +8 more
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Abstract Crimean‐Congo hemorrhagic fever (CCHF) is an infection caused by a tick‐borne virus (genus: Nairovirus, family: Bunyaviridae). The most important vector for CCHF is the ixodid tick. Along with tick bite, direct contact with the virus‐affected animal is responsible for its spread. Pakistan witnessed its first case of CCHF in 1976 and has been a
Shehroze Tabassum +5 more
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Nairobi sheep disease (NSD) is a hemorrhagic vector‐borne disease of small ruminants caused by the Nairobi sheep disease virus (NSDV), also known as Ganjam virus (GV). NSDV and GV refer to the same virus. The NSDV has been identified in East Africa, India, Sri Lanka, and China, and NSDV vector ticks can be carried by birds. There is few research on the
KwangHyok Kim +4 more
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Mapping of Antibody Epitopes on the Crimean-Congo Hemorrhagic Fever Virus Nucleoprotein
Crimean-Congo hemorrhagic fever virus (CCHFV), a nairovirus, is a tick-borne zoonotic virus that causes hemorrhagic fever in humans. The CCHFV nucleoprotein (NP) is the antigen most used for serological screening of CCHFV infection in animals and humans.
Boniface Pongombo Lombe +9 more
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