Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases. [PDF]
PLoS ONE, 2019 Tick-borne nairoviruses (order Bunyavirales) encode an ovarian tumor domain protease (OTU) that suppresses the innate immune response by reversing the post-translational modification of proteins by ubiquitin (Ub) and interferon-stimulated gene product 15
John V Dzimianski +7 more
doaj +2 more sources
Kupe Virus, a New Virus in the Family Bunyaviridae, Genus Nairovirus, Kenya
Emerging Infectious Diseases, 2009 We have previously described isolation and preliminary identification of a virus related to Dugbe virus (DUGV), family Bunyaviridae, genus Nairovirus.
Mary Crabtree +2 more
doaj +2 more sources
Inhibition of Hazara nairovirus replication by small interfering RNAs and their combination with ribavirin [PDF]
Virology Journal, 2011 Background The genus Nairovirus in the family Bunyaviridae contains 34 tick-borne viruses classified into seven serogroups. Hazara virus (HAZV) belongs to the Crimean-Congo hemorrhagic fever (CCHF) serogroup that also includes CCHF virus (CCHFV) a major ...
Crance Jean-Marc +5 more
doaj +2 more sources
Bunyavirus-Vector Interactions [PDF]
Viruses, 2014 The Bunyaviridae family is comprised of more than 350 viruses, of which many within the Hantavirus, Orthobunyavirus, Nairovirus, Tospovirus, and Phlebovirus genera are significant human or agricultural pathogens.
Kate McElroy Horne +1 more
doaj +2 more sources
Viruses, 2017 This report describes the near complete genomic sequence and subsequent analysis of Vinegar Hill virus (VINHV; tentative member of the genus Orthonairovirus, family Nairoviridae, order Bunyavirales). VINHV is the second nairovirus reported to be isolated
Penelope J. Gauci +5 more
doaj +2 more sources
Cranberry (Vaccinium macrocarpon) Extract Impairs Nairovirus Infection by Inhibiting the Attachment to Target Cells [PDF]
Pathogens, 2021 Hazara virus (HAZV) belongs to the Nairoviridae family and is included in the same serogroup of the Crimean-Congo hemorrhagic fever virus (CCHFV). CCHFV is the most widespread tick-borne arbovirus. It is responsible for a serious hemorrhagic disease, for
Mattia Mirandola +7 more
doaj +2 more sources
Metagenomic Nanopore Sequencing of Tickborne Pathogens, Mongolia [PDF]
Emerging Infectious DiseasesWe performed nanopore-based metagenomic screening on 885 ticks collected from 6 locations in Mongolia and divided the results into 68 samples: 23 individual samples and 45 pools of 2–12 tick samples each.
Koray Ergunay +11 more
doaj +2 more sources
Virome Diversity and Zoonotic Risks of Haemaphysalis concinna Ticks in Northeastern China. [PDF]
Transbound Emerg DisHaemaphysalis concinna is a prevalent tick vector in Northeastern China, exhibiting a broad host range and the capacity to transmit over 40 human pathogens. Although numerous virome studies have investigated this tick species in Northeastern China, individual‐level viral prevalence, coinfection dynamics, and the host spectra of the harbored pathogenic ...
Liu J +11 more
europepmc +2 more sources
Structural and cellular biology of the nairovirus nucleocapsid protein [PDF]
, 2014 Crimean Congo haemorrhagic fever virus (CCHFV) is a tick borne nairovirus responsible for a highly fatal human disease with increased recent incidence within the human population of southern Europe.
Surtees, Rebecca A
core +7 more sources
Metatranscriptomic Analysis Uncovers RNA Virus Diversity in Ticks From the China-Russia-North Korea Border Region. [PDF]
Transbound Emerg DisTicks serve as critical viral vectors, and border regions, acting as convergence zones of complex ecosystems, provide diverse habitats for ticks and their hosts, thereby underscoring the need to investigate the tick‐borne virome composition in such areas. In this study, metatranscriptomic analysis of five tick species, namely Haemaphysalis longicornis,
Liu Z +14 more
europepmc +2 more sources