Saurashtra region is highly affected by presence of highly contagious zoonotic disease. Crimean-Congo Hemorrhagic Fever is cause by tick borne virus belonging Bunyaviridae family. Eleven confirm cases of CCHF were identified in Bhavnagar District during
Bansi J Trivedi, Atul V Trivedi
doaj +1 more source
Mutations in the Schmallenberg virus Gc glycoprotein facilitate cellular protein synthesis shutoff and restore pathogenicity of NSs deletion mutants in mice [PDF]
Serial passage of viruses in cell culture has been traditionally used to attenuate virulence and identify determinants of viral pathogenesis. In a previous study, we found that a strain of Schmallenberg virus (SBV) serially passaged in tissue culture ...
Aislynn Taggart +13 more
core +1 more source
Homage to Richard M. Elliott [PDF]
No abstract ...
Brennan, Benjamin +2 more
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Early Bunyavirus-Host Cell Interactions
The Bunyaviridae is the largest family of RNA viruses, with over 350 members worldwide. Several of these viruses cause severe diseases in livestock and humans.
Amelina Albornoz +3 more
doaj +1 more source
The nonstructural protein NSs of Schmallenberg virus is targeted to the nucleolus and induces nucleolar disorganization [PDF]
Schmallenberg virus (SBV) was discovered in Germany in late 2011 and then spread rapidly to many European countries. SBV is an orthobunyavirus that causes abortion and congenital abnormalities in ruminants.
Breard, Emmanuel +13 more
core +3 more sources
Human and murine IFIT1 proteins do not restrict infection of negative-sense RNA viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae families [PDF]
UNLABELLED: Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) is a host protein with reported cell-intrinsic antiviral activity against several RNA viruses.
Amarasinghe, Gaya +12 more
core +3 more sources
The role of platelets in the pathogenesis of viral hemorrhagic fevers. [PDF]
Viral hemorrhagic fevers (VHF) are acute zoonotic diseases that, early on, seem to cause platelet destruction or dysfunction. Here we present the four major ways viruses affect platelet development and function and new evidence of molecular factors that ...
Juan C Zapata +2 more
doaj +1 more source
Mapping of transcription termination within the S segment of SFTS phlebovirus facilitated the generation of NSs-deletant viruses [PDF]
SFTS phlebovirus (severe fever with thrombocytopenia syndrome virus; SFTSV) is an emerging tick-borne bunyavirus that was first reported in China in 2009. Here we report the generation of a recombinant SFTSV (rHB29NSsKO) that cannot express the viral non-
Brennan, Benjamin +2 more
core +1 more source
Diffusion and Home Range Parameters for Rodents: Peromyscus maniculatus in New Mexico [PDF]
We analyze data from a long term field project in New Mexico, consisting of repeated sessions of mark-recaptures of Peromyscus maniculatus (Rodentia: Muridae), the host and reservoir of Sin Nombre Virus (Bunyaviridae: Hantavirus).
Abramson +28 more
core +3 more sources
Schmallenberg virus: emergence of an Orthobunyavirus among ruminants in Western Europe [PDF]
Recently, a novel virus has been identified among ruminants in Western Europe. This virus, the so-called Schmallenberg virus, belongs to the family Bunyaviridae, genus Orthobunyavirus, serogroup Simbu and is closely related to Akabane, Aino and Shamonda ...
Bertels, Guido +3 more
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