Results 51 to 60 of about 4,960 (172)

Laboratory Data Analysis of Hemorrhagic Fever With Renal Syndrome Patients to Predict Disease Severity and Patient Prognosis

Journal of Clinical Laboratory Analysis, Volume 39, Issue 23, December 2025.
Prompt access to care with proper treatment is essential for preventing patients from developing renal failure and unfavorable outcomes. This study aimed to elucidate laboratory parameters associated with HFRS severity and prognosis to predict disease course and initiate prompt clinical management.
Hong Shi, Feng Du, Ting Wang, Zhendong Gu, Ting Ruan, Qiujian Zhao, Rui Xu, Yi Wang, Langxi Luo, Shaohua Wang, Liejun Jiang, Yaoni Li   +11 more
wiley   +1 more source

Breeding for quantitative disease resistance: Case studies, emerging approaches, and exploiting pathogen variation

Crop Science, Volume 65, Issue 6, November/December 2025.
Abstract Host resistance, using qualitative genes with major effects, such as resistance (R) genes, is one of the most effective disease control strategies. However, because major gene‐derived resistance wanes over time, breeders must increasingly focus on quantitative trait loci and minor effect genes, which, when pyramided together, can confer ...
R. McGee, M. Zaleski‐Cox, M. A. Jayawardana, B. L. Tillman, O. Wally, L. Esquivel‐Garcia, W. G. D. Fernando, H. Raman, H. S. Bariana, T. Copley, A. H. Carter, V. Hoyos‐Villegas   +11 more
wiley   +1 more source

The structure of the hantavirus zinc finger domain is conserved and represents the only natively folded region of the Gn cytoplasmic tail

Frontiers in Microbiology, 2011
Hantaviruses, of the family Bunyaviridae, are present throughout the world and cause a variety of infections ranging from the asymptomatic to mild and severe hemorrhagic fevers. Hantaviruses are enveloped anti-sense RNA viruses that contain three genomic
D. Fernando eEstrada, Michael eConner, Stephen C. St. Jeor, Roberto N. De Guzman   +3 more
doaj   +1 more source

Epidemiologic relationship between Toscana virus infection and Leishmania infantum due to common exposure to Phlebotomus perniciosus sandfly vector. [PDF]

PLoS Neglected Tropical Diseases, 2011
Sand flies are recognised vectors of parasites in the genus Leishmania and a number of arthropod-borne viruses, in particular viruses within the genus Phlebovirus, family Bunyaviridae.
Laurence Bichaud, Marc Souris, Charles Mary, Laëtitia Ninove, Laurence Thirion, Raphaël P Piarroux, Renaud Piarroux, Xavier De Lamballerie, Rémi N Charrel   +8 more
doaj   +1 more source

A Pyrido‐Quinoxaline Derivative That Downregulates Reticulon 3 Protein Exhibits Potent Antiviral Activity Against Zika Virus

Journal of Medical Virology, Volume 97, Issue 9, September 2025.
ABSTRACT In the wake of the COVID‐19 pandemic, awareness of emerging pathogens has significantly increased, prompting greater investment in research and preparedness. In this context, arboviral diseases are recognized as unmet medical challenges due to their rapid spread. Notably, the geographical range of several flaviviral diseases is expanding: Zika
Erika Plicanti, Andrea Deiana, Silvia Nottoli, Giulia Lottini, Roberta Ibba, Sandra Piras, Carlo Di Marzo, Silvia Vegni, Michele Lai, Mauro Pistello, Antonio Carta, Giulia Freer   +11 more
wiley   +1 more source

Biogeography of Tick-Borne Bhanja Virus (Bunyaviridae) in Europe

Interdisciplinary Perspectives on Infectious Diseases, 2009
Bhanja virus (BHAV) is pathogenic for young domestic ruminants and also for humans, causing fever and affections of the central nervous system. This generally neglected arbovirus of the family Bunyaviridae is transmitted by metastriate ticks of the ...
Zdenek Hubálek
doaj   +1 more source

Alteration in superoxide dismutase 1 causes oxidative stress and p38 MAPK activation following RVFV infection. [PDF]

PLoS ONE, 2011
Rift Valley fever (RVF) is a zoonotic disease caused by Rift Valley fever virus (RVFV). RVFV is a category A pathogen that belongs to the genus Phlebovirus, family Bunyaviridae. Understanding early host events to an infectious exposure to RVFV will be of
Aarthi Narayanan, Taissia Popova, Michael Turell, Jessica Kidd, Jessica Chertow, Serguei G Popov, Charles Bailey, Fatah Kashanchi, Kylene Kehn-Hall   +8 more
doaj   +1 more source

Short‐Term Effects of Meteorological Factors on Severe Fever With Thrombocytopenia Syndrome Incidence in Xinyang, China

GeoHealth, Volume 9, Issue 8, August 2025.
From 1 January 2013 to 31 December 2023 a total of 6,601 cases of SFTS were reported in Xinyang. The incidence of SFTS exhibits evident seasonality, commencing from March and gradually escalating from April, peaking between May and June, followed by a decline with reduced incidence after October.
Quanman Hu, Yan Hu, Yanyan Yang, Jundong Chen, Songshan Zhang, Fei Zhao, Saiwei Lu, Li Zhang, Shuaiyin Chen, Guangcai Duan   +9 more
wiley   +1 more source

Lymphopenia: An early indicator of Crimean‐Congo haemorrhagic fever

Tropical Medicine &International Health, Volume 30, Issue 8, Page 831-837, August 2025.
Abstract Objectives Crimean‐Congo haemorrhagic fever is a lethal tick‐borne disease characterised by initially nonspecific symptoms. While thrombocytopenia and leucopenia are established diagnostic markers, there is a need for earlier indicators. This study evaluates lymphopenia as a marker for Crimean‐Congo haemorrhagic fever.
Hatice Bozkurt Yavuz, Hüseyin Haydar Kutlu   +1 more
wiley   +1 more source

Na+ and K+ Concentration and Regulation of Protein Synthesis in L-A9 and Aedes albopictus Cells Infected with Marituba Virus (Bunyaviridae)

Journal of General Virology, 1989
Infection of L-A9 cells with Marituba virus produces a severe inhibition of protein synthesis. This inhibition is temporally correlated with an increase in the intracellular Na+ concentration and a decrease in the intracellular K+ concentration. However, in Marituba virus-infected Aedes albopictus cells the intracellular level of Na+ and K+ ions and ...
I C, Frugulhetti, M A, Rebello
openaire   +2 more sources