Results 61 to 70 of about 812,660 (211)

Novel camelid antibody fragments targeting recombinant nucleoprotein of Araucaria hantavirus: a prototype for an early diagnosis of Hantavirus Pulmonary Syndrome. [PDF]

PLoS ONE, 2014
In addition to conventional antibodies, camelids produce immunoglobulins G composed exclusively of heavy chains in which the antigen binding site is formed only by single domains called VHH.
Soraya S Pereira, Leandro S Moreira-Dill, Michelle S S Morais, Nidiane D R Prado, Marcos L Barros, Andrea C Koishi, Giovanny A C A Mazarrotto, Giselle M Gonçalves, Juliana P Zuliani, Leonardo A Calderon, Andreimar M Soares, Luiz H Pereira da Silva, Claudia N Duarte dos Santos, Carla F C Fernandes, Rodrigo G Stabeli   +14 more
doaj   +1 more source

A Novel Machine Learning Approach for Predicting Prognosis of SFTS Patients in the Early Stages of Disease

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Objective Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick‐borne disease characterized by high morbidity and mortality rates. Timely detection and prognosis prediction are critical for implementing effective clinical interventions.
Siqi Li, Ting Wang, Rujia Chen, Yun Wang, Renren Ouyang, Wei Wei, Feng Wang, Shiji Wu, Hongyan Hou, Mahmoud Elhaig   +9 more
wiley   +1 more source

Role of Bunyamwera Orthobunyavirus NSs protein in infection of mosquito cells. [PDF]

PLoS Neglected Tropical Diseases, 2012
Bunyamwera orthobunyavirus is both the prototype and study model of the Bunyaviridae family. The viral NSs protein seems to contribute to the different outcomes of infection in mammalian and mosquito cell lines.
Agnieszka M Szemiel, Anna-Bella Failloux, Richard M Elliott   +2 more
doaj   +1 more source

Laboratory Data Analysis of Hemorrhagic Fever With Renal Syndrome Patients to Predict Disease Severity and Patient Prognosis

Journal of Clinical Laboratory Analysis, Volume 39, Issue 23, December 2025.
Prompt access to care with proper treatment is essential for preventing patients from developing renal failure and unfavorable outcomes. This study aimed to elucidate laboratory parameters associated with HFRS severity and prognosis to predict disease course and initiate prompt clinical management.
Hong Shi, Feng Du, Ting Wang, Zhendong Gu, Ting Ruan, Qiujian Zhao, Rui Xu, Yi Wang, Langxi Luo, Shaohua Wang, Liejun Jiang, Yaoni Li   +11 more
wiley   +1 more source

The dynamics of natural Plasmodium falciparum infections. [PDF]

, 2012
BACKGROUND: Natural immunity to Plasmodium falciparum has been widely studied, but its effects on parasite dynamics are poorly understood. Acquisition and clearance rates of untreated infections are key elements of the dynamics of malaria, but estimating
Ingrid Felger (92160), Beck, Hans-Peter, Sama, W., Beck, H. P., Tiaden, A., Hans-Peter Beck, Bretscher, M., Nicole Falk (134915), Owusu-Agyei, Seth, Beck Hans-Peter, Felger Ingrid, Felger, Ingrid, Sama, Wilson, Sama Wilson, Maire, Martin, Tiaden, André, Ingrid Felger, Falk, Nicole, Wilson Sama (134920), Thomas A. Smith (95630), Wilson Sama, Bretscher, Michael T, André Tiaden, Seth Owusu-Agyei (80063), Tiaden André, Bretscher Michael T., Owusu-Agyei, S., Felger, I., Seth Owusu-Agyei, Owusu-Agyei Seth, Smith, T. A., Hans-Peter Beck (129757), Maire Martin, Martin Maire (134910), André Tiaden (134918), Michael T Bretscher, Michael T. Bretscher (134912), Falk Nicole, Martin Maire, Smith, Thomas A, Thomas A Smith, Falk, N., Maire, N., Nicole Falk, Smith Thomas A.   +44 more
core   +1 more source

Biogeography of Tick-Borne Bhanja Virus (Bunyaviridae) in Europe

Interdisciplinary Perspectives on Infectious Diseases, 2009
Bhanja virus (BHAV) is pathogenic for young domestic ruminants and also for humans, causing fever and affections of the central nervous system. This generally neglected arbovirus of the family Bunyaviridae is transmitted by metastriate ticks of the ...
Zdenek Hubálek
doaj   +1 more source

The structure of the hantavirus zinc finger domain is conserved and represents the only natively folded region of the Gn cytoplasmic tail

Frontiers in Microbiology, 2011
Hantaviruses, of the family Bunyaviridae, are present throughout the world and cause a variety of infections ranging from the asymptomatic to mild and severe hemorrhagic fevers. Hantaviruses are enveloped anti-sense RNA viruses that contain three genomic
D. Fernando eEstrada, Michael eConner, Stephen C. St. Jeor, Roberto N. De Guzman   +3 more
doaj   +1 more source

Breeding for quantitative disease resistance: Case studies, emerging approaches, and exploiting pathogen variation

Crop Science, Volume 65, Issue 6, November/December 2025.
Abstract Host resistance, using qualitative genes with major effects, such as resistance (R) genes, is one of the most effective disease control strategies. However, because major gene‐derived resistance wanes over time, breeders must increasingly focus on quantitative trait loci and minor effect genes, which, when pyramided together, can confer ...
R. McGee, M. Zaleski‐Cox, M. A. Jayawardana, B. L. Tillman, O. Wally, L. Esquivel‐Garcia, W. G. D. Fernando, H. Raman, H. S. Bariana, T. Copley, A. H. Carter, V. Hoyos‐Villegas   +11 more
wiley   +1 more source

Epidemiologic relationship between Toscana virus infection and Leishmania infantum due to common exposure to Phlebotomus perniciosus sandfly vector. [PDF]

PLoS Neglected Tropical Diseases, 2011
Sand flies are recognised vectors of parasites in the genus Leishmania and a number of arthropod-borne viruses, in particular viruses within the genus Phlebovirus, family Bunyaviridae.
Laurence Bichaud, Marc Souris, Charles Mary, Laëtitia Ninove, Laurence Thirion, Raphaël P Piarroux, Renaud Piarroux, Xavier De Lamballerie, Rémi N Charrel   +8 more
doaj   +1 more source

A Pyrido‐Quinoxaline Derivative That Downregulates Reticulon 3 Protein Exhibits Potent Antiviral Activity Against Zika Virus

Journal of Medical Virology, Volume 97, Issue 9, September 2025.
ABSTRACT In the wake of the COVID‐19 pandemic, awareness of emerging pathogens has significantly increased, prompting greater investment in research and preparedness. In this context, arboviral diseases are recognized as unmet medical challenges due to their rapid spread. Notably, the geographical range of several flaviviral diseases is expanding: Zika
Erika Plicanti, Andrea Deiana, Silvia Nottoli, Giulia Lottini, Roberta Ibba, Sandra Piras, Carlo Di Marzo, Silvia Vegni, Michele Lai, Mauro Pistello, Antonio Carta, Giulia Freer   +11 more
wiley   +1 more source