Results 11 to 20 of about 4,296 (209)

NSs: the multifaceted bunyavirus virulence factor. [PDF]

Npj Viruses
Abstract Bunyaviricetes represents a diverse class of RNA viruses, including hundreds of species distributed worldwide that threaten human and animal health. This Perspective briefly overviews bunyaviruses infecting humans and other mammals, focusing on their key virulence factor, the nonstructural protein NSs. By subverting host
Duboeuf M, Legrand AF, Lozach PY, Maisse C.   +3 more
europepmc   +7 more sources

Transcription of a Recombinant Bunyavirus RNA Template by Transiently Expressed Bunyavirus Proteins [PDF]

Virology, 1995
We describe a convenient system for analyzing bunyavirus transcription using a recombinant RNA template derived from the plasmid pBUNSCAT, which comprises a negative-sense reporter gene (chloramphenicol acetyltransferase or CAT) flanked by the exact 5' and 3' untranslated regions of the Bunyamwera virus (BUN) S RNA segment.
Dunn, Ewan F., Pritlove, David C., Jin, Hong, Elliott, Richard M.   +3 more
openaire   +3 more sources

A rare fatal case of a novel bunyavirus-associated hemophagocytic lymphohistiocytosis [PDF]

Journal of Infection in Developing Countries, 2016
Herein we describe a rare fatal case of a novel bunyavirus-associated hemophagocytic lymphohistiocytosis (HLH) in a 62-year-old female patient. The novel bunyavirus infects patients with or without HLH who have similar clinical features such as fever ...
Ling Lin, You-Zu Xu, Xiao-Mai Wu, Hong-Fei Ge, Jia-Xi Feng, Mei-Fang Chen, Dong-Qing Lv, Bo-Li Li, Jian Lin   +8 more
doaj   +3 more sources

Modulation of Potassium Channels Inhibits Bunyavirus Infection [PDF]

Journal of Biological Chemistry, 2016
Bunyaviruses are considered to be emerging pathogens facilitated by the segmented nature of their genome that allows reassortment between different species to generate novel viruses with altered pathogenicity. Bunyaviruses are transmitted via a diverse range of arthropod vectors, as well as rodents, and have established a global disease range with ...
Hover, S, King, B, Hall, B, Loundras, E-A, Taqi, H, Daly, J, Dallas, M, Peers, C, Schnettler, E, McKimmie, C, Kohl, A, Barr, JN, Mankouri, J   +12 more
openaire   +6 more sources

Illuminating bunyavirus entry into host cells with fluorescence [PDF]

Molecular Microbiology, 2023
AbstractBunyavirales constitute the largest order of enveloped RNA viruses, many members of which cause severe diseases in humans and domestic animals. In recent decades, innovative fluorescence‐based methods have paved the way to visualize and track single fluorescent bunyaviral particles in fixed and live cells.
Gu, Yu, Lozach, Pierre‐yves
openaire   +5 more sources

Genome Sequences of a Novel Vietnamese Bat Bunyavirus [PDF]

Genome Announcements, 2016
ABSTRACT To document the viral zoonotic risks in Vietnam, fecal samples were systematically collected from a number of mammals in southern Vietnam and subjected to agnostic deep sequencing. We describe here novel Vietnamese bunyavirus sequences detected in bat feces. The complete L and S segments from 14 viruses were determined.
Oude Munnink, Bas B., Phan, My Vu Tra, Hoek, Lia van der, Kellam, Paul, Cotten, Matthew, Kiet, Bach Tuan, Baker, Stephen, Berto, Alessandra, Boni, Maciej F., Bryant, Juliet E., Phu, Bui Duc, Campbell, James I., Carrique-Mas, Juan, Hung, Dang Manh, Huong, Dang Thao, Oanh, Dang Tram, Day, Jeremy N., Van Tan, Dinh, van Doorn, H. Rogier, Han, Duong An, Farrar, Jeremy J., Trang, Hau Thi Thu, Nghia, Ho Dang Trung, Long, Hoang Bao, Van Duong, Hoang, Thu, Huynh Thi Kim, Cuong, Lam Chi, Hung, Le Manh, Phuong, Le Thanh, Phuc, Le Thi, Phuong, Le Thi, Luat, Le Xuan, Thu Ha, Luu Thi, Van Chuong, Ly, Loan, Mai Thi Phuoc, Nadjm, Behzad, Bao, Ngo Thanh, Hoa, Ngo Thi, Tue, Ngo Tri, Tu, Nguyen Canh, Thuan, Nguyen Dac, Dong, Nguyen, Chuyen, Nguyen Khac, An, Nguyen Ngoc, Vinh, Nguyen Ngoc, Hung, Nguyen Quoc, Dung, Nguyen Thanh, Minh, Nguyen Thanh, Binh, Nguyen Thi, Tham, Nguyen Thi Hong, Tien, Nguyen Thi Hong, Chuc, Nguyen Thi Kim, Ngoc, Nguyen Thi Le, Ha, Nguyen Thi Lien, Lien, Nguyen Thi Nam, Diep, Nguyen Thi Ngoc, Nhung, Nguyen Thi, Chau, Nguyen Thi Song, Chi, Nguyen Thi Yen, Trinh, Nguyen Thieu, Van, Nguyen Thu, Van Cuong, Nguyen, Van Hung, Nguyen, Van Kinh, Nguyen, Hoang, Nguyen Van Minh, Van My, Nguyen, Van Thang, Nguyen, Van Thanh, Nguyen, Van Vinh Chau, Nguyen, Van Xang, Nguyen, My, Pham Ha, Anh, Pham Hong, Khoa, Pham Thi Minh, Tam, Pham Thi Thanh, Van Lao, Pham, Van Minh, Pham, Van Be Bay, Phan, My, Phan Vu Tra, Rabaa, Maia A., Rahman, Motiur, Thompson, Corinne, Thwaites, Guy, Ngan, Ta Thi Dieu, Nhu, Tran Do Hoang, Chau, Tran Hoang Minh, Toan, Tran Khanh, Phuc, Tran My, Hong, Tran Thi Kim, Dung, Tran Thi Ngoc, Thanh, Tran Thi Thanh, Minh, Tran Thi Thuy, Nguyen, Tran Thua, Hien, Tran Tinh, Tri, Trinh Quang, Hien, Vo Be, Tai, Vo Nhut, Cuong, Vo Quoc, Phat, Voong Vinh, Huong, V. U Thi Lan, Hang, Vu Thi Ty, Wertheim, Heiman, Bogaardt, Carlijn, Chase-Topping, Margo, Ivens, A. L., Lu, Lu; id_orcid 0000-0002-9330-7022, Nyugen, Dung, Rambaut, Andrew, Simmonds, Peter, Woolhouse, Mark; id_orcid 0000-0003-3765-8167, Deijs, Martin, Jebbink, Maarten F., Jazaeri Farsani, Seyed Mohammad, Dodd, Kimberly, Euren, Jason, Lucas, Ashley, Ortiz, Nancy, Pennacchio, Len, Rubin, Edward, Saylors, Karen E., Hai, Tran Minh, Wolfe, Nathan D.   +120 more
openaire   +11 more sources

Recent Progress in Bunyavirus Research [PDF]

, 2017
The Bunyaviridae is the largest family of RNA viruses, with over 350 isolates worldwide distributed into five genera (i.e., Hantavirus, Orthobunyavirus, Nairovirus, Tospovirus, and Phlebovirus). Many of these viruses are significant human or agricultural pathogens.
Pierre-Yves Lozach, Jane Tao
core   +5 more sources

Mechanisms of bunyavirus morphogenesis and egress

Journal of General Virology, 2023
Unlike many segmented negative-sense RNA viruses, most members of the Bunyavirales bud at Golgi membranes, as opposed to the plasma membrane. Central players in this assembly process are the envelope glycoproteins, Gn and Gc, which upon translation undergo proteolytic processing, glycosylation and trafficking to the Golgi, where they interact with ...
Jake Barker, Luis L. P. daSilva, Colin M. Crump   +2 more
openaire   +3 more sources

Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress [PDF]

, 2021
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging negatively stranded enveloped RNA bunyavirus that causes SFTS with a high case fatality rate of up to 30%.
Xue-jie Yu (523802), Li-na Yan (11656231), Wen-kang Zhang (11656228), Chuan-min Zhou (8861861), Jia-min Yan (11656225), Yong-Jun Jiao (5958053)   +5 more
core   +1 more source

Development of Rice Stripe Tenuivirus Minireplicon Reverse Genetics Systems Suitable for Analyses of Viral Replication and Intercellular Movement

Frontiers in Microbiology, 2021
Rice stripe virus (RSV), a tenuivirus with four negative-sense/ambisense genome segments, is one of the most devastating viral pathogens affecting rice production in many Asian countries.
Xiaoyan Zhang, Kai Sun, Yan Liang, Shuo Wang, Kaili Wu, Zhenghe Li, Zhenghe Li, Zhenghe Li   +7 more
doaj   +1 more source