Results 11 to 20 of about 4,622 (197)

NSs: the multifaceted bunyavirus virulence factor. [PDF]

Npj Viruses
Abstract Bunyaviricetes represents a diverse class of RNA viruses, including hundreds of species distributed worldwide that threaten human and animal health. This Perspective briefly overviews bunyaviruses infecting humans and other mammals, focusing on their key virulence factor, the nonstructural protein NSs. By subverting host
Duboeuf M, Legrand AF, Lozach PY, Maisse C.   +3 more
europepmc   +6 more sources

Visualizing the ribonucleoprotein content of single bunyavirus virions reveals more efficient genome packaging in the arthropod host [PDF]

Communications Biology, 2021
Bermúdez-Méndez et al. describe a FISH-immunofluorescence method that allows simultaneous visualization of bunyavirus genome segments and virions at single-molecule resolution.
Erick Bermúdez-Méndez, Eugene A. Katrukha, Cindy M. Spruit, Jeroen Kortekaas, Paul J. Wichgers Schreur   +4 more
doaj   +2 more sources

A rare fatal case of a novel bunyavirus-associated hemophagocytic lymphohistiocytosis [PDF]

Journal of Infection in Developing Countries, 2016
Herein we describe a rare fatal case of a novel bunyavirus-associated hemophagocytic lymphohistiocytosis (HLH) in a 62-year-old female patient. The novel bunyavirus infects patients with or without HLH who have similar clinical features such as fever ...
Ling Lin, You-Zu Xu, Xiao-Mai Wu, Hong-Fei Ge, Jia-Xi Feng, Mei-Fang Chen, Dong-Qing Lv, Bo-Li Li, Jian Lin   +8 more
doaj   +2 more sources

Transcription of a Recombinant Bunyavirus RNA Template by Transiently Expressed Bunyavirus Proteins

Virology, 1995
We describe a convenient system for analyzing bunyavirus transcription using a recombinant RNA template derived from the plasmid pBUNSCAT, which comprises a negative-sense reporter gene (chloramphenicol acetyltransferase or CAT) flanked by the exact 5' and 3' untranslated regions of the Bunyamwera virus (BUN) S RNA segment.
Dunn, Ewan F., Pritlove, David C., Jin, Hong, Elliott, Richard M.   +3 more
openaire   +3 more sources

Modulation of Potassium Channels Inhibits Bunyavirus Infection [PDF]

Journal of Biological Chemistry, 2016
Bunyaviruses are considered to be emerging pathogens facilitated by the segmented nature of their genome that allows reassortment between different species to generate novel viruses with altered pathogenicity. Bunyaviruses are transmitted via a diverse range of arthropod vectors, as well as rodents, and have established a global disease range with ...
Hover, S, King, B, Hall, B, Loundras, E-A, Taqi, H, Daly, J, Dallas, M, Peers, C, Schnettler, E, McKimmie, C, Kohl, A, Barr, JN, Mankouri, J   +12 more
openaire   +6 more sources

Genome Sequences of a Novel Vietnamese Bat Bunyavirus [PDF]

Genome Announcements, 2016
ABSTRACT To document the viral zoonotic risks in Vietnam, fecal samples were systematically collected from a number of mammals in southern Vietnam and subjected to agnostic deep sequencing. We describe here novel Vietnamese bunyavirus sequences detected in bat feces. The complete L and S segments from 14 viruses were determined.
Oude Munnink, Bas B., Phan, My Vu Tra, Hoek, Lia van der, Kellam, Paul, Cotten, Matthew, Kiet, Bach Tuan, Baker, Stephen, Berto, Alessandra, Boni, Maciej F., Bryant, Juliet E., Phu, Bui Duc, Campbell, James I., Carrique-Mas, Juan, Hung, Dang Manh, Huong, Dang Thao, Oanh, Dang Tram, Day, Jeremy N., Van Tan, Dinh, van Doorn, H. Rogier, Han, Duong An, Farrar, Jeremy J., Trang, Hau Thi Thu, Nghia, Ho Dang Trung, Long, Hoang Bao, Van Duong, Hoang, Thu, Huynh Thi Kim, Cuong, Lam Chi, Hung, Le Manh, Phuong, Le Thanh, Phuc, Le Thi, Phuong, Le Thi, Luat, Le Xuan, Thu Ha, Luu Thi, Van Chuong, Ly, Loan, Mai Thi Phuoc, Nadjm, Behzad, Bao, Ngo Thanh, Hoa, Ngo Thi, Tue, Ngo Tri, Tu, Nguyen Canh, Thuan, Nguyen Dac, Dong, Nguyen, Chuyen, Nguyen Khac, An, Nguyen Ngoc, Vinh, Nguyen Ngoc, Hung, Nguyen Quoc, Dung, Nguyen Thanh, Minh, Nguyen Thanh, Binh, Nguyen Thi, Tham, Nguyen Thi Hong, Tien, Nguyen Thi Hong, Chuc, Nguyen Thi Kim, Ngoc, Nguyen Thi Le, Ha, Nguyen Thi Lien, Lien, Nguyen Thi Nam, Diep, Nguyen Thi Ngoc, Nhung, Nguyen Thi, Chau, Nguyen Thi Song, Chi, Nguyen Thi Yen, Trinh, Nguyen Thieu, Van, Nguyen Thu, Van Cuong, Nguyen, Van Hung, Nguyen, Van Kinh, Nguyen, Hoang, Nguyen Van Minh, Van My, Nguyen, Van Thang, Nguyen, Van Thanh, Nguyen, Van Vinh Chau, Nguyen, Van Xang, Nguyen, My, Pham Ha, Anh, Pham Hong, Khoa, Pham Thi Minh, Tam, Pham Thi Thanh, Van Lao, Pham, Van Minh, Pham, Van Be Bay, Phan, My, Phan Vu Tra, Rabaa, Maia A., Rahman, Motiur, Thompson, Corinne, Thwaites, Guy, Ngan, Ta Thi Dieu, Nhu, Tran Do Hoang, Chau, Tran Hoang Minh, Toan, Tran Khanh, Phuc, Tran My, Hong, Tran Thi Kim, Dung, Tran Thi Ngoc, Thanh, Tran Thi Thanh, Minh, Tran Thi Thuy, Nguyen, Tran Thua, Hien, Tran Tinh, Tri, Trinh Quang, Hien, Vo Be, Tai, Vo Nhut, Cuong, Vo Quoc, Phat, Voong Vinh, Huong, V. U Thi Lan, Hang, Vu Thi Ty, Wertheim, Heiman, Bogaardt, Carlijn, Chase-Topping, Margo, Ivens, A. L., Lu, Lu; id_orcid 0000-0002-9330-7022, Nyugen, Dung, Rambaut, Andrew, Simmonds, Peter, Woolhouse, Mark; id_orcid 0000-0003-3765-8167, Deijs, Martin, Jebbink, Maarten F., Jazaeri Farsani, Seyed Mohammad, Dodd, Kimberly, Euren, Jason, Lucas, Ashley, Ortiz, Nancy, Pennacchio, Len, Rubin, Edward, Saylors, Karen E., Hai, Tran Minh, Wolfe, Nathan D.   +120 more
openaire   +10 more sources

Illuminating bunyavirus entry into host cells with fluorescence

Molecular Microbiology, 2023
AbstractBunyavirales constitute the largest order of enveloped RNA viruses, many members of which cause severe diseases in humans and domestic animals. In recent decades, innovative fluorescence‐based methods have paved the way to visualize and track single fluorescent bunyaviral particles in fixed and live cells.
Gu, Yu, Lozach, Pierre‐yves
openaire   +5 more sources

Multimeric single-domain antibody complexes protect against bunyavirus infections [PDF]

eLife, 2020
The World Health Organization has included three bunyaviruses posing an increasing threat to human health on the Blueprint list of viruses likely to cause major epidemics and for which no, or insufficient countermeasures exist.
Paul J Wichgers Schreur, Sandra van de Water, Michiel Harmsen, Erick Bermúdez-Méndez, Dubravka Drabek, Frank Grosveld, Kerstin Wernike, Martin Beer, Andrea Aebischer, Olalekan Daramola, Sara Rodriguez Conde, Karen Brennan, Dorota Kozub, Maiken Søndergaard Kristiansen, Kieran K Mistry, Ziyan Deng, Jan Hellert, Pablo Guardado-Calvo, Félix A Rey, Lucien van Keulen, Jeroen Kortekaas   +20 more
doaj   +3 more sources

Methods to produce bunyavirus replicon particles

, 2012
The invention relates to methods of producing infectious bunyavirus replicon particles. These bunyavirus replicon particles are safe and can be used outside a biosafety containment.
KORTEKAAS JEROEN ALEXANDER, MOORMANN ROBERTUS JACOBUS MARIA   +1 more
openaire   +7 more sources

Vesicular Stomatitis Virus Chimeras Expressing the Oropouche Virus Glycoproteins Elicit Protective Immune Responses in Mice

mBio, 2021
Oropouche virus (OROV) infection of humans is associated with a debilitating febrile illness that can progress to meningitis or encephalitis. First isolated from a forest worker in Trinidad and Tobago in 1955, the arbovirus OROV has since been detected ...
Sarah Hulsey Stubbs, Marjorie Cornejo Pontelli, Nischay Mishra, Changhong Zhou, Juliano de Paula Souza, Rosa Maria Mendes Viana, W. Ian Lipkin, David M. Knipe, Eurico Arruda, Sean P. J. Whelan   +9 more
doaj   +1 more source