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Terminal Genome Sequences of the Soft Tick Bunyavirus
The complete genome sequence of the soft tick bunyavirus (STBV) was obtained using the Sanger sequencing technique. Comparison with other viral sequences revealed that STBV has unique sequences in the terminal regions that are highly conserved among the genus Orthonairovirus .
Satoko Sugimoto +6 more
openalex +3 more sources
Mapping of transcription termination within the S segment of SFTS phlebovirus facilitated the generation of NSs-deletant viruses [PDF]
SFTS phlebovirus (severe fever with thrombocytopenia syndrome virus; SFTSV) is an emerging tick-borne bunyavirus that was first reported in China in 2009. Here we report the generation of a recombinant SFTSV (rHB29NSsKO) that cannot express the viral non-
Brennan, Benjamin +2 more
core +1 more source
Neuroattenuated bunyavirus variant: derivation, characterization, and revertant clones [PDF]
A neuroattenuated variant bunyavirus, designated RFC/25B.5 (B.5), was selected by serial passage of a reassortant clone (RFC virus) of a California serogroup virus in BHK-21 cells, followed by plaque purification of that passaged stock. Based on its virulence index (ratio of PFU/50% lethal dose), clone B5 was over 40,000-fold less virulent than its ...
M. Endres +3 more
openalex +4 more sources
No Evidence of Gouléako and Herbert Virus Infections in Pigs, Côte d’Ivoire and Ghana
A recent report suggested that 2 novel bunyaviruses discovered in insects in Côte d’Ivoire caused lethal disease in swine in South Korea. We conducted cell culture studies and tested serum from pigs exposed to mosquitoes in Côte d’Ivoire and Ghana and ...
Sandra Junglen +11 more
doaj +1 more source
Antiviral Activity of Acetylsalicylic Acid against Bunyamwera Virus in Cell Culture
The Bunyavirales order is a large group of RNA viruses that includes important pathogens for humans, animals and plants. With high-throughput screening of clinically tested compounds we have looked for potential inhibitors of the endonuclease domain of a
Sara Yolanda Fernández-Sánchez +3 more
doaj +1 more source
Culex tarsalis is a competent vector species for Cache Valley virus [PDF]
Background: Cache Valley virus (CVV) is a mosquito-borne orthobunyavirus endemic in North America. The virus is an important agricultural pathogen leading to abortion and embryonic lethality in ruminant species, especially sheep.
Alto, Barry W. +10 more
core +1 more source
The family Bunyaviridae consists of over 300 virus species and strains that are divided into 5 genera: orthobunyavirus, hantavirus, nairovirus, phlebovirus, and tospovirus. All members of family Bunyaviridae possess a negative-sense, single stranded tripartite RNA genome, consisting of large (L), medium (M) and small (S) segments, which encode an RNA ...
Kumiko, Yoshimatsu, Jiro, Arikawa
openaire +3 more sources
In recent years, several newly discovered tick-borne viruses causing a wide spectrum of diseases in humans have been ascribed to the Phlebovirus genus of the Bunyaviridae family.
Veronica V. Rezelj +5 more
doaj +1 more source
Because parasites have an inextricable relationship with their host, they have the potential to serve as viral reservoirs or facilitate virus host shifts.
Nolwenn M. Dheilly +3 more
doaj +1 more source
Mutations in the Schmallenberg virus Gc glycoprotein facilitate cellular protein synthesis shutoff and restore pathogenicity of NSs deletion mutants in mice [PDF]
Serial passage of viruses in cell culture has been traditionally used to attenuate virulence and identify determinants of viral pathogenesis. In a previous study, we found that a strain of Schmallenberg virus (SBV) serially passaged in tissue culture ...
Aislynn Taggart +13 more
core +1 more source

