Results 51 to 60 of about 6,619 (255)

Transcription of a Recombinant Bunyavirus RNA Template by Transiently Expressed Bunyavirus Proteins

open access: yesVirology, 1995
We describe a convenient system for analyzing bunyavirus transcription using a recombinant RNA template derived from the plasmid pBUNSCAT, which comprises a negative-sense reporter gene (chloramphenicol acetyltransferase or CAT) flanked by the exact 5' and 3' untranslated regions of the Bunyamwera virus (BUN) S RNA segment.
Dunn, Ewan F.   +3 more
openaire   +2 more sources

Reverse genetics approaches for the development of bunyavirus vaccines [PDF]

open access: yesCurrent Opinion in Virology, 2020
The Bunyavirales order is the largest group of RNA viruses, which includes important human and animal pathogens, that cause serious diseases. Licensed vaccines are often not available for many of these pathogens. The establishment of bunyavirus reverse genetics systems has facilitated the generation of recombinant infectious viruses, which have been ...
Breanna Tercero, Shinji Makino
openaire   +2 more sources

Recent Advances in Bunyavirus Reverse Genetics Research: Systems Development, Applications, and Future Perspectives

open access: yesFrontiers in Microbiology, 2021
Bunyaviruses are members of the Bunyavirales order, which is the largest group of RNA viruses, comprising 12 families, including a large group of emerging and re-emerging viruses.
Fuli Ren   +14 more
doaj   +1 more source

Novel Phlebovirus with Zoonotic Potential Isolated from Ticks, Australia

open access: yesEmerging Infectious Diseases, 2014
Recently discovered tick-borne phleboviruses have been associated with severe disease and death among persons in Asia and the United States. We report the discovery of a novel tick phlebovirus in Tasmania State, Australia, that is closely related to ...
Jianning Wang   +14 more
doaj   +1 more source

Analysis of the medium (M) segment sequence of Guaroa virus and its comparison to other orthobunyaviruses [PDF]

open access: yes, 2004
Guaroa virus (GROV), a segmented virus in the genus Orthobunyavirus, has been linked to the Bunyamwera serogroup (BUN) through cross-reactivity in complement fixation assays of S segment-encoded nucleocapsid protein determinants, and also to the ...
Briese, Thomas   +2 more
core   +2 more sources

Recent Progress in Bunyavirus Research [PDF]

open access: yes, 2017
The Bunyaviridae is the largest family of RNA viruses, with over 350 isolates worldwide distributed into five genera (i.e., Hantavirus, Orthobunyavirus, Nairovirus, Tospovirus, and Phlebovirus). Many of these viruses are significant human or agricultural pathogens.
Pierre-Yves Lozach, Jane Tao
openaire   +3 more sources

Interferon-stimulated gene (ISG)-expression screening reveals the specific antibunyaviral activity of ISG20 [PDF]

open access: yes, 2018
Bunyaviruses pose a significant threat to human health, prosperity and food security. In response to viral infections, interferons (IFNs) upregulate the expression of hundreds of interferon stimulated genes (ISGs) whose cumulative action can potently ...
Bieniasz, Paul D.   +15 more
core   +1 more source

Hantavirus Induced Kidney Disease

open access: yesFrontiers in Medicine, 2022
Hantavirus induced hemorrhagic fever with renal syndrome (HFRS) is an emerging viral zoonosis affecting up to 200,000 humans annually worldwide. This review article is focused on recent advances in the mechanism, epidemiology, diagnosis, and treatment of
Sheema Mir
doaj   +1 more source

Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]

open access: yes, 2013
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Bottcher, B.   +4 more
core   +1 more source

A Novel Bunyavirus Discovered in Oriental Shrimp (Penaeus chinensis)

open access: yesFrontiers in Microbiology, 2021
Herein, we describe a novel bunyavirus, oriental wenrivirus 1 (OWV1), discovered in moribund oriental shrimp (Penaeus chinensis) collected from a farm in China in 2016.
Xuan Dong   +19 more
doaj   +1 more source

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