Results 101 to 110 of about 76,850 (268)

Structural Requirements of Human Ether-a-go-go–  related Gene Channels for Block by Bupivacaine [PDF]

, 2007
Cornelia C. Siebrands, Patrick Friederich   +1 more
openalex   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

Experimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S. Prabhu, Kate Karelina, Eric E. Kelley, Randy W. Bryner, Dharendra Thapa, Paul D. Chantler   +11 more
wiley   +1 more source

A comparative study of analgesic effects of ketamine, fentanyl and saline added to hyperbaric bupivacaine for central neuraxial blockade in total knee replacement surgery

, 2021
Janaki Subhadra Peyyety, Dyva Manogna Reddypogu, Kiranmye Mukku, Aloka Samantaray, Sameera Vani Prasad, M. H. Rao   +5 more
openalex   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source

Epidural dexmedetomidine infusion for perioperative analgesia in patients undergoing abdominal cancer surgery: randomized trial

Journal of Pain Research, 2018
Diab Fuad Hetta,1 Khaled Mohamed Fares,1 Abualauon Mohamed Abedalmohsen,2 Amani Hassan Abdel-Wahab,2 Ghada Mohammed Abo Elfadl,2 Wesam Nashat Ali2 1Anesthesia and Pain Management, South Egypt Cancer Institute, 2Anesthesia and Intensive Care, Faculty of ...
Hetta DF, Fares KM, Abedalmohsen AM, Abdel-Wahab AH, Abo Elfadl GM, Ali WN   +5 more
doaj  

4D ultrasound reveals regional left atrial strain remodelling in a murine model of reversible pressure overload

The Journal of Physiology, EarlyView.
Abstract figure legend Traditional planar imaging approaches of the left atrium do not capture complex geometry. Four‐dimensional imaging allows the acquisition of 3D data + time to visualize left atrial geometry and kinematics. We designed an advanced analysis technique to investigate left atrial biomechanics in a model of pressure overload and ...
John P. Salvas, Thomas Moore‐Morris, Craig J. Goergen, Pierre Sicard   +3 more
wiley   +1 more source

Efficacy profile of liposome bupivacaine, a novel formulation of bupivacaine for postsurgical analgesia

Journal of Pain Research, 2012
Sergio D Bergese1, Sonia Ramamoorthy2, Gary Patou3, Kenneth Bramlett4, Stephen R Gorfine5, Keith A Candiotti61Department of Anesthesiology and Neurological Surgery, Ohio State University, Columbus, OH, USA; 2Department of Surgery, University of ...
Candiotti KA, Gorfine SR, Bramlett K, Patou G, Ramamoorthy S, Bergese SD   +5 more
doaj  

Comparative characteristics of the effectiveness of spinal anesthesia with intrathecal administration of bupivacaine and its combination with adjuvants

Медицина неотложных состояний
Background. Currently, there is active discussion regarding the effectiveness of different adjuvants in spinal anesthesia. Objective: to compare the effectiveness of dexmedetomidine and fentanyl as adjuvants in combination with intrathecal bupivacaine ...
Ye.E. Shchegolkov
doaj   +1 more source

Selective Deletion of NBCe1 in Reactive Astrocytes Attenuates Ischemic Stroke Brain Damage

Glia, Volume 73, Issue 12, Page 2386-2406, December 2025.
Main Points NBCe1 is upregulated in reactive astrocytes following ischemic stroke. Deletion of astrocytic Nboe1 reduces stroke volume, preserves AQP4 polarization, reduces BBB permeability, and improves neurological function after ischemic stroke. ABSTRACT The electrogenic sodium bicarbonate transporter 1 (NBCe1/Slc4a4), predominantly expressed in ...
Okan Capuk, Elise Berthold, Kathiravan Kaliyappan, Mansi Avunoori, Rajesh Muduganti, Sanjana Krishna, Shamseldin Metwally, Mary McFarland, Shanshan Song, Victoria Fiesler, Sydney Fischer, Lesley M. Foley, T. Kevin Hitchens, Susannah Waxman, Ian A. Sigal, Shefeeq M. Theparambil, Gulnaz Begum   +16 more
wiley   +1 more source

Differences in sensory nerve block between levobupivacaine and bupivacaine at low concentrations in humans and animals.

PLoS ONE
Physiochemical properties of levobupivacaine and bupivacaine are identical, but pharmacokinetic and pharmacodynamics properties differ due to stereoselective interactions at the molecular sites of action.
Akiyuki Sakamoto, Satoshi Tanaka, Takashi Ishida, Mikito Kawamata   +3 more
doaj   +1 more source