Results 101 to 110 of about 104,086 (361)

Enhanced expression of WD repeat-containing protein 35 via CaMKK/AMPK activation in bupivacaine-treated Neuro2a cells. [PDF]

PLoS ONE, 2014
We previously reported that bupivacaine induces reactive oxygen species (ROS) generation, p38 mitogen-activated protein kinase (MAPK) activation and nuclear factor-kappa B activation, resulting in an increase in expression of WD repeat-containing protein
Lei Huang, Fumio Kondo, Masahiko Gosho, Guo-Gang Feng, Misako Harato, Zhong-yuan Xia, Naohisa Ishikawa, Yoshihiro Fujiwara, Shoshiro Okada   +8 more
doaj   +1 more source

Prenatal alcohol exposure increases the aggressiveness of estrogen‐induced pituitary tumors in male rats

Alcohol, Clinical and Experimental Research, EarlyView.
Prenatal alcohol exposure (PAE) enhances the development of aggressive pituitary tumors (PitNETs) in female rats. In this study, we found that PAE also promotes the development of PitNETs in male rats. Like in females, PAE treatment enhances the expression of stem cell and tumor aggressiveness genes and increases tumor cell proliferation rate ...
Shaista Chaudhary, Dipak K. Sarkar
wiley   +1 more source

An evaluation of the analgesic effect of AnestaGel™ on mechanical allodynia in a rat model of postoperative incisional pain

Journal of Pain Research, 2017
Jacob Hutchins,1 William Taylor2 1Department of Anesthesiology, University of Minnesota, Minneapolis, MN, USA; 2InSitu Biologics, LLC, St Paul, MN, USA Purpose: Sustained release hydrogel with bupivacaine (AnestaGel™) is a novel formulation of ...
Hutchins J, Taylor W
doaj  

Efficacy of low dose bupivacaine with intrathecal fentanyl for cesarean section on maternal hemodynamic: Systemic review and meta-analysis

Saudi Journal of Anaesthesia, 2019
Hypotension during spinal Anesthesia is the most common complication with maternal and neonatal morbidity and mortality. Low dose bupivacaine with intrathecal fentanyl is recommended as strategy to prevent spinal Anesthesia induced hypotension and ...
Semagn Mekonnen Abate, Akine Eshete Belihu   +1 more
doaj   +1 more source

Tourniquetless Total Knee Arthroplasty With Modern Perioperative Protocols Decreases Pain and Opioid Consumption in Women [PDF]

, 2018
Background This study examined whether a modern total knee arthroplasty (TKA) protocol without a tourniquet results in less patient-reported pain and in-hospital opioid consumption compared to TKA with a tourniquet.
Dilley, Julian E., Hood, Mark, Jr., Kheir, Michael M., Meneghini, R. Michael, Ziemba-Davis, Mary   +4 more
core   +1 more source

Comparison of two peripheral regional analgesic techniques for primary elective total hip arthroplasty: a randomised clinical trial

Anaesthesia, EarlyView.
Summary Introduction Several regional anaesthesia techniques have been used in the peri‐operative pain management of patients who undergo primary elective total hip arthroplasty. The erector spinae plane, pericapsular nerve group and lateral femoral cutaneous nerve blocks offer motor‐sparing analgesia of the hip region but target different areas.
Francesca Buffoli, Claudia Bonetti, Camilla Pugno, Andrea Minini, Silvia Bettinelli, Arianna Mancini, Alessandro Colombi, Alberto Benigni, Edward R. Mariano, Luca F. Lorini, Dario Bugada   +10 more
wiley   +1 more source

Intrapartum epidural analgesia and breastfeeding: a prospective cohort study [PDF]

, 2016
BACKGROUND Anecdotal reports suggest that the addition of fentanyl (an opioid) to epidural analgesia for women during childbirth results in difficulty establishing breastfeeding.
Ellwood, David A, Roberts, Christine L, Simpson, Judy M, Thompson, Jane F, Torvaldsen, Siranda   +4 more
core   +1 more source

Time to Analgesia Onset and Pharmacokinetics After Separate and Combined Administration of Liposome Bupivacaine and Bupivacaine HCl: Considerations for Clinicians

The Open Orthopaedics Journal, 2016
Background: Liposome bupivacaine is a prolonged-release bupivacaine formulation indicated for single-dose administration into the surgical site to produce postsurgical analgesia.
J. Gadsden, W. J. Long
semanticscholar   +1 more source

Impact of age at first visit on glycolipid metabolism, bone metabolism, and fertility potential in patients with Klinefelter syndrome

Andrology, EarlyView.
Abstract Background Classic Klinefelter syndrome (KS) is characterized by one extra X chromosome (47, XXY), leading to hypergonadotropic hypogonadism and higher risk of alterations in glycolipid homeostasis, cardiovascular diseases, and low bone mineral density. Most frequently, KS is diagnosed in adulthood because of infertility.
Giordana Ferraioli, Andrea Graziani, Noemi Sagone, Andrea Di Nisio, Massimo Iafrate, Fabrizio Dal Moro, Alberto Ferlin, Andrea Garolla   +7 more
wiley   +1 more source

Bupivacaine 0.5 % versus articaine 4 % for the removal of lower third molars. A crossover randomized controlled trial [PDF]

, 2011
Objective: To compare the anesthetic action of 0.5% bupivacaine in relation to 4% articaine, both with 1:200,000 epinephrine, in the surgical removal of lower third molars. As a secondary objective hemodynamic changes using both anesthetics were analyzed.
Berini Aytés, Leonardo, Gay Escoda, Cosme, Paredes García, Jordi, Sancho Puchades, Manuel, Valmaseda Castellón, E., Vílchez Pérez, Miguel Angel   +5 more
core   +1 more source