Results 81 to 90 of about 57,563 (245)

The free energy of biomembrane and nerve excitation and the role of anesthetics

, 2018
In the electromechanical theory of nerve stimulation, the nerve impulse consists of a traveling region of solid membrane in a liquid environment. Therefore, the free energy necessary to stimulate a pulse is directly related to the free energy difference ...
Heimburg, Thomas, Jackson, Andrew D., Music, Tea, Wang, Tian   +3 more
core   +1 more source

Intrapartum epidural analgesia and breastfeeding: a prospective cohort study [PDF]

, 2016
BACKGROUND Anecdotal reports suggest that the addition of fentanyl (an opioid) to epidural analgesia for women during childbirth results in difficulty establishing breastfeeding.
Ellwood, David A, Roberts, Christine L, Simpson, Judy M, Thompson, Jane F, Torvaldsen, Siranda   +4 more
core   +1 more source

Flecainide binding dynamics in voltage‐gated sodium channels: A comparative isoform analysis of the state‐dependent block

British Journal of Pharmacology, EarlyView.
Background and Purpose Local anaesthetics and class I anti‐arrhythmic drugs block voltage‐gated Na+ channels, but the molecular basis for the isoform differences in drug sensitivity remains unclear. Understanding these mechanisms is essential for optimizing therapeutic efficacy and safety.
Tatsuo Munakata, Etsuko Kumada, Nao Katayama, Hiroki Nakagawa, Akihiko Sunami   +4 more
wiley   +1 more source

Outcomes of intra-articular corticosteroid injections for adolescents with hip pain. [PDF]

, 2017
Intra-articular injection of corticosteroid and anesthetic (CSI) is a useful diagnostic tool for hip pain secondary to labral tears or femoroacetabular impingement (FAI).
Pandya, Nirav K, Tangtiphaiboontana, Jennifer, Zhang, Alan L   +2 more
core   +2 more sources

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

Local anaesthetic bupivacaine induced ovarian and prostate cancer apoptotic cell death and underlying mechanisms in vitro

, 2016
Retrospective studies indicate that the use of regional anesthesia can reduce cancer recurrence after surgery which could be due to ranging from immune function preservation to direct molecular mechanisms.
Chen, L, Hankin, J, Ma, D, Xuan, W, Yao, S, Zhao, H   +5 more
core   +3 more sources

Global survey on the utilisation and experiences with different retrobulbar anaesthesia techniques in horses

Equine Veterinary Journal, EarlyView.
Abstract Background Retrobulbar anaesthesia (RBA) is relevant for ocular surgery in standing sedated horses. Objectives Gathering insights on experiences with RBA techniques. Study Design Cross‐sectional survey. Methods An online survey collected information on the respondents' professional background, indications, injection methods, use of ultrasound ...
Simona Lieberth, Katharina Thieme, Christian Dancker, Roswitha Merle, Johanna Corinna Eule   +4 more
wiley   +1 more source

Safety and Efficacy of LockeT Suture Retention Device for Large‐Bore Venous Access Closure

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Electrophysiology (EP) procedures increasingly require large‐bore venous access (LBVA), which is associated with a higher risk of vascular complications. While vascular closure devices (VCDs) are well established for arterial access, data on venous closure—particularly for LBVA—remain limited.
Pedro J. Diaz Delgado, Aashish Katapadi, Eli Herink, Karnik Patel, Donita Atkins, Rajesh Kabra, Naga Venkata K. Pothineni, Douglas Darden, Rakesh Gopinathannair, Dhanunjaya Lakkireddy   +9 more
wiley   +1 more source

Clinical evaluation of epidural bupivacaine, butorphanol, and butorphanol -bupivacaine combination in goat

Journal of Veterinary Medical Research, 2019
Butorphanol is a synthetic opioid commonly used for epidural anesthesia in human either alone or in combination with bupivacaine but not in goat. The objective of the present study was to evaluate the analgesic effect of epidural butorphanol either alone
Hagag U., Mahmoud M.M.
doaj  

New patents on topical anesthetics. [PDF]

, 2014
Anesthesia is defined as a total or partial loss of sensation and it may be general, local or topical, depending on the method of drug administration and area of the body affected.
CALVIERI, Stefano, CANTISANI, CARMEN, D'ANDREA, Vito, Frascani, F, MACALUSO, LAURA, paolino, giovanni, RICHETTA, Antonio Giovanni   +6 more
core   +1 more source