Results 131 to 140 of about 80,732 (295)

Improved Chondrotoxic Profile of Liposomal Bupivacaine Compared With Standard Bupivacaine After Intra-articular Infiltration in a Porcine Model

open access: yes, 2017
Background:Increasingly, liposomal bupivacaine is being used with multimodal pain management strategies. In vitro investigations have shown decreased chondrotoxicity profiles for liposomal bupivacaine; however, there is no evidence regarding its in vivo ...
Craig D. Cameron   +7 more
core   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

open access: yesExperimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer   +11 more
wiley   +1 more source

Inotropic effect of β-adrenergic agonists in bupivacaine-intoxicated rats.

open access: yes, 2018
(A) and (B) Bupivacaine significantly reduced LVSP and +dp/ptmax, while isoprenalin and adrenalin induced a further reduction of LVSP and +dp/ptmax. (C) and (D) Bupivacaine significantly increased LVEDP and -dp/ptmax, while isoprenalin and adrenalin did ...
Li Chu (459196)   +11 more
core   +1 more source

Ovariectomy, but not moderate intermittent hypoxia, promotes respiratory instability and risk of obesity in adult female rats

open access: yesExperimental Physiology, EarlyView.
Abstract Sleep apnoea (SA) is a prevalent and complex respiratory disorder associated with recurrent interruptions of air flow during sleep. SA causes sleep fragmentation and intermittent hypoxia which leads to numerous negative health consequences.
Marianne Gagnon   +5 more
wiley   +1 more source

Epidural dexmedetomidine infusion for perioperative analgesia in patients undergoing abdominal cancer surgery: randomized trial

open access: yesJournal of Pain Research, 2018
Diab Fuad Hetta,1 Khaled Mohamed Fares,1 Abualauon Mohamed Abedalmohsen,2 Amani Hassan Abdel-Wahab,2 Ghada Mohammed Abo Elfadl,2 Wesam Nashat Ali2 1Anesthesia and Pain Management, South Egypt Cancer Institute, 2Anesthesia and Intensive Care, Faculty of ...
Hetta DF   +5 more
doaj  

The Comparison of Bupivacaine-Tramadol Combination With Bupivacaine-Fentanyl and Plain Bupivacaine in Epidural Anesthesia

open access: yes, 2002
In this study, the properties of epidural anesthesia with 0.5% bupivacaine and tramadol was compared with epidural anesthesia using bupivacaine-fentanyl or plain bupivacaine.
Ökeşli, S.   +4 more
core  

Mitochondrial Ca2+ uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray   +16 more
wiley   +1 more source

The effect of ozonation of bupivacaine on bupivacaine-induced neurotoxicity in rats

open access: yes
Bupivacaine-induced neurotoxicity (BIN) is common condition associated with free oxygen radicals based degenerative cellular changes. Morever, a apoptotic damages increase the occurences of the BIN.
Harbelioğlu, Mehmet Ali   +2 more
core   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen   +5 more
wiley   +1 more source

Direct Vasocontractile Activities of Bupivacaine Enantiomers on the Isolated Rat Thoracic Aorta

open access: yes, 2020
Background. In vitro studies with isolated arteries have shown direct vasoactivity of racemic bupivacaine. However, there is little information on the direct vasoactivities of bupivacaine enantiomers, S(−)-and R(+)-bupivacaine. Methods.
Maki Mizogami, Mai Mukozawa, Ko Takakura
core  

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