Results 141 to 150 of about 80,732 (295)

Tonotopically distinct OFF responses arise in the mouse auditory midbrain following sideband suppression

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sounds of different frequencies elicit spatially distinct patterns of neural activity within the inferior colliculus aligned to the tonotopic organization of afferent projections. Sound‐evoked neural responses can be visualized in awake mice that express fluorescent Ca2+ sensors.
Patrick D. Parker   +2 more
wiley   +1 more source

4D ultrasound reveals regional left atrial strain remodelling in a murine model of reversible pressure overload

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Traditional planar imaging approaches of the left atrium do not capture complex geometry. Four‐dimensional imaging allows the acquisition of 3D data + time to visualize left atrial geometry and kinematics. We designed an advanced analysis technique to investigate left atrial biomechanics in a model of pressure overload and ...
John P. Salvas   +3 more
wiley   +1 more source

Diving into the unknown: Evidence of enhanced skeletal muscle lactate efflux potential and blood–muscle exchange in competitive breath‐hold divers

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Competitive breath‐hold divers exhibit skeletal muscle characteristics indicative of enhanced blood‐muscle exchange capacity and increased lactate efflux potential. Top left: Participant characteristics, matched for age, height, body mass, and maximal oxygen uptake (V̇O2max${\dot{\mathrm{V}}}\rm{O}_{\rm{2max}}$).
Antonis Elia   +7 more
wiley   +1 more source

Comparison of liposomal bupivacaine and regular bupivacaine in the transversus abdominis plane for postoperative analgesia: an updated systematic review and meta-analysis

open access: yesBMC Anesthesiology
Objectives Liposome bupivacaine is a long-acting anesthetic to prolong the duration of analgesia. However, the effectiveness of liposome bupivacaine for providing prolonged analgesia with transversus abdominis plane (TAP) blocks remains uncertain ...
Shuyan Liu   +3 more
doaj   +1 more source

A comparison of single dose caudal tramadol, tramadol plus bupivacaine and bupivacaine administration for postoperative analgesia in children

open access: yes, 2001
PubMedID: 11359591Background: Our aim was to compare the effect of single dose caudal tramadol, tramadol plus bupivacaine and bupivacaine on the management of postoperative pain in children.
Ozcengiz D.   +3 more
core   +1 more source

P2X3 receptor antagonism improves hindlimb blood flow during exercise in a conscious ovine model of hypertensive heart failure with preserved ejection fraction

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A preclinical large‐animal model of hypertensive heart failure with preserved ejection fraction (HFpEF) was used to examine the role of purinergic P2X3 receptor signalling during treadmill exercise. Animals were instrumented with either thoracic cardiac output and coronary flow probes or abdominal renal and hindlimb blood flow ...
Mridula Pachen   +7 more
wiley   +1 more source

Differences in sensory nerve block between levobupivacaine and bupivacaine at low concentrations in humans and animals.

open access: yesPLoS ONE
Physiochemical properties of levobupivacaine and bupivacaine are identical, but pharmacokinetic and pharmacodynamics properties differ due to stereoselective interactions at the molecular sites of action.
Akiyuki Sakamoto   +3 more
doaj   +1 more source

Comparative characteristics of the effectiveness of spinal anesthesia with intrathecal administration of bupivacaine and its combination with adjuvants

open access: yesМедицина неотложных состояний
Background. Currently, there is active discussion regarding the effectiveness of different adjuvants in spinal anesthesia. Objective: to compare the effectiveness of dexmedetomidine and fentanyl as adjuvants in combination with intrathecal bupivacaine ...
Ye.E. Shchegolkov
doaj   +1 more source

Removal of bupivacaine and isoprenalin restored cell contractility.

open access: yes, 2018
(A) and (B) Representative sarcomere shortening perfused with bupivacaine in the presence or absence of isoprenalin, and after washing with Tyrode’s solution.
Li Chu (459196)   +11 more
core   +1 more source

Postoperative Pain Treatment After Pancreatic Surgery: A Systematic Review With Meta‐Analyses and Trial Sequential Analyses

open access: yesEuropean Journal of Pain, Volume 30, Issue 10, November 2026.
ABSTRACT Background Major pancreatic surgery is associated with significant postoperative pain that impairs early mobilisation and recovery. ERAS guidelines for pancreaticoduodenectomy recommend multimodal opioid‐sparing analgesia, with a strong recommendation for epidural analgesia and continuous wound infiltration as an alternative.
Caroline D. Lassen   +5 more
wiley   +1 more source

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