Results 151 to 160 of about 43,264 (217)

A Role for Glycine Transporter‐2 Inhibitors in Regulating Accumbal Dopamine Levels and Voluntary Alcohol Intake in Rats

Alcohol, Clinical and Experimental Research, Volume 50, Issue 9, September 2026.
Partial inhibition of glycine transporter‐2 (GlyT2) elevates basal dopamine levels in the nucleus accumbens and abolishes the alcohol deprivation effect in rats. The findings reveal a role for GlyT2‐expressing glycinergic neurons in regulating mesolimbic dopamine signaling and relapse‐like alcohol drinking, highlighting GlyT2 as a potential target for ...
Yasmin Olsson, Klara Danielsson, Ana Domi, Helga Lidö, Linda Engström Ruud, Mia Ericson, Bo Söderpalm   +6 more
wiley   +1 more source

In Vitro Effects of Anaesthetic Compounds on a Panel of Solid Tumour Cell Lines—An Exploratory Study

Journal of Cellular and Molecular Medicine, Volume 30, Issue 18, September 2026.
ABSTRACT Anaesthetic agents are essential for surgical procedures, yet their potential role on tumour cell biology remains incompletely understood. Emerging evidence suggests that these compounds can act both as protumor and antitumor agents, influencing cellular processes such as proliferation, migration and cell death mechanisms.
Olga Grajdieru, Alexandru Cristian Sabo, Adrian Bogdan Tigu, Andrei Ivancuta, Cristian Silviu Moldovan, Andrada Uhl, Miruna Cristina Ungurenasu, Andrada‐Ioana Balmez, Ada Moisescu, Simina Pîrv, Madalina Nistor, Ximena‐Maria Muresan, Diana Cenariu, Ciprian Tomuleasa, Catalin Constantinescu   +14 more
wiley   +1 more source

Liposomal bupivacaine surgical site injection for decrease of narcotic use in hip fractures: a pilot multicenter randomized trial. [PDF]

OTA Int
Matuszewski PE, Jo J, Aneja A, Diwan A, Kraus MT, Moghadamian ES, Wright RD, Siegel J, Thompson K, Swart EF.   +9 more
europepmc   +1 more source

Specific Knockdown of Gene Expression in the Mature Rat Pineal Gland: The Cone‐Rod Homeodomain Transcription Factor Regulates Melatonin Synthesis In Vivo

Journal of Pineal Research, Volume 78, Issue 5, September 2026.
ABSTRACT Melatonin is synthesised from tryptophan by the sequential action of enzymes that are highly expressed in the pineal gland. Homeobox gene‐encoded transcription factors typically control organ development; however, a set of homeobox genes is strongly expressed in the adult pineal gland.
Nicole Anne Morrissey, Tenna Bering, Aurea Susana Blancas‐Velázquez, Jakob Albrethsen, Nicolai J. Wewer Albrechtsen, Martin Fredensborg Rath   +5 more
wiley   +1 more source

Analgesic Efficacy of Continuous Bupivacaine Infusion versus Liposomal Bupivacaine in Parasacral Ischial Plane Block After Total Knee Arthroplasty: An Open-Label, Randomized, Controlled, Non-Inferiority Study. [PDF]

Drug Des Devel Ther
Pan X, Ye P, Xie Y, Chen Y, Fan H, Huang Y, Zheng C, Zheng X, Zheng T.   +8 more
europepmc   +1 more source

Paediatric perioperative hypersensitivity reactions: Analysis of the French GERAP network database

Pediatric Allergy and Immunology, Volume 37, Issue 9, September 2026.
Graphical abstract of the pediatric perioperative hypersensitivity reactions recorded in the GERAP network datbase between 1997 and 2024. Abstract Background Perioperative hypersensitivity (POH) reactions are rare but potentially life‐threatening and remain poorly characterised in children.
Mertes Paul Michel, Pouessel Guillaume, Gouel Aurélie, Karila Chantal, Lejus‐Bourdeau Corinne, Franchina Sébastien, Tacquard Charles, For the GERAP Network, Perquin Mélanie, Husser Solenne, Morisset Martine, Huynh Vinh An, Charansol Angéline, Hanniet Anatole, Florence Lakkis‐Castelain, Bordes Demolis Maryline, Giraudon Antoine, Pellerin Christelle, Vaia Elleni, Mariotte Delphine, Mure Marion, Ollivier Yann, Serrier Julien, Dalampira Georgia, Baud Charlotte, Muti Daniela, Schoeller Estelle, Capo‐Chichi Rosita, Seltzer Sandrine, Vandenberghe Durr Sophie, Pottier Eloïse, Zambelli Valentina, Mear Amélie, Facon Alain, Ledesve D'heudieres Pierre, Pelletier De Chambure Diane, Caron Juliette, Delebarre‐Sauvage Christine, Pouessel Guillaume, Bellet Elisabeth, Orsel Isabelle, Le Quang Diane, Tezier Marie, Boghossian Marie‐Caroline, Fargeas Marine, Fresco Raphaëlle, Gouitaa Marion, Billard Carine, Lefevre Sébastien, Chiriac Anca, Demoly Pascal, Fayard Blandine, Beaugendre Isabelle, Colas Luc, El Hanache, Aguinet Emmanuelle, Petit Isabelle, Rezzadori Gilles, Pallancher Stéphanie, Miran Sophie, Patel Minaxi, Merzouk Aicha, Smilov Magdalena, Barakat Leyla, Dechaisemartin Luc, Gouel‐Cheron Aurélie, Neukirch Catherine, Martin Aurélie, Merlin Karine, Bailleul Amaury, Demiri Migena, Fessenmeyer Christine, Karila‐Beaulier Chantal, Lepage David, Gest Noémie, Seringulian Alice, Taing Diane, Hamon Gautier, Verliere Ambre, Saf Sarah, Lequipe Johan, Renauld Valérie, Malinovsky Jean‐Marc, Dessard Sabrina, Le Guillou Lisa, Rochefort‐Morel Cecile, Franchina Sébastien, Girard Emmanuel, Nafeh Samer, Delzanno Cédric, Dzviga Charles, Million‐Charrel Justine, Minguy Nolwenn, Tacquard Charles, Viville Simon, Le Guen Morgan, Gayraud Jacques, Gil Céline, Maihol Claire, Migueres Isabelle, Chassery Clément, Herry Julie, Hoarau Cyrille, Barakat Leyla, Faivre Sébastien   +104 more
wiley   +1 more source

Interpreting the Efficacy of Liposomal Bupivacaine in Fascial Plane Blocks for Elderly Patients: A Methodological Reappraisal [Letter]. [PDF]

Drug Des Devel Ther
Gai H, Hou Y, Yu Y.
europepmc   +1 more source

Zygomatic Sialadenitis as a Rare Cause of Exophthalmos in a Dog

Veterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Objective To describe the clinical presentation, diagnostic findings, and surgical management of zygomatic sialadenitis associated with retrobulbar disease in a dog following extensive dental extractions. Animals Studied A 10‐year‐old spayed female Cavalier King Charles Spaniel.
Katrina E. V. Jones, Manabu Kurihara, Hans D. Westermeyer, Danielle Meritet   +3 more
wiley   +1 more source

Comparison of effectiveness and safety of spinal anaesthesia with 0.25% versus 0.5% hyperbaric bupivacaine for endoscopic urological procedures: A prospective randomised controlled trial. [PDF]

Indian J Anaesth
Verma AK, Mishra N, Kumar A.
europepmc   +1 more source

Hippocampal long‐range GABAergic neurons target hippocampal‐projecting cells of the supramammillary area

The Journal of Physiology, Volume 604, Issue 18, Page 7924-7956, 15 September 2026.
Abstract figure legend The hippocampus contains a diversity of inhibitory neurons, including somatostatin‐expressing (SST+) and neuronal nitric oxide synthase‐expressing (NOS+) projection neurons that target extrahippocampal brain regions, including the hypothalamic supramammillary area (SuM).
Lauren Glassburn, Edmund Havener, Olivia Stangler, Ezequiel Marron Fernandez de Velasco, Esther Krook‐Magnuson   +4 more
wiley   +1 more source