Results 121 to 130 of about 104,116 (405)

Method for Successfully Inducting Individuals Who Use Illicit Fentanyl Onto Buprenorphine/Naloxone.

American Journal on Addictions, 2020
BACKGROUND AND OBJECTIVES Individuals exposed to fentanyl are at risk of precipitated withdrawal using typical buprenorphine/naloxone induction procedures.
Denis G. Antoine, A. Huhn, E. Strain, Gavin Turner, Jasmyne Jardot, A. Hammond, K. Dunn   +6 more
semanticscholar   +1 more source

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

Advanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying, Qi Wang, Dejian Li, Yao Wang, Pengfang Zhang, Chengqing Yi, Rui Zhu   +6 more
wiley   +1 more source

Low Barrier Tele-Buprenorphine in the Time of COVID-19: A Case Report

Journal of addiction medicine, 2020
Background: To reduce the spread of coronavirus disease 2019 (COVID-19), many substance use disorder treatment programs have transitioned to telemedicine. Emergency regulatory changes allow buprenorphine initiation without an in-person visit. We describe
M. Harris, Samantha Johnson, Sarah Mackin, R. Saitz, A. Walley, Jessica L. Taylor   +5 more
semanticscholar   +1 more source

Neural Response Reliability as a Marker of the Transition of Neural Codes along Auditory Pathways

Advanced Science, EarlyView.
Decoding sound from neural activity in mice reveals a striking shift in how the brain encodes sound: from precise but redundant timing codes in early auditory areas to efficient, synergistic rate‐based codes in the cortex. This transformation highlights a robust neural strategy for turning complex acoustic input into coherent perception across the ...
Alexa Buck, Typhaine Dupont, Rupert Andrews Cavanagh, Olivier Postal, Jérôme Bourien, Jean‐Luc Puel, Nicolas Michalski, Boris Gourévitch   +7 more
wiley   +1 more source

Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome. [PDF]

, 2011
AIMS: More than half of infants exposed to opioids in utero develop neonatal abstinence syndrome (NAS) of severity to require pharmacological therapy. Current treatments are associated with prolonged hospitalization.
Abdel-Latif, Agthe, American Academy of Pediatrics Committee on Drugs, Blaser, Coghlan, Colombini, Coyle, Crocetti, Dryden, Dysart, Finnegan, Jackson, Jansson, Johnson, Jones, Kraft, Lainwala, Langenfeld, Mamelle, Nandakumar, O'Grady, Oei, Osborn, Osborn, Sarkar, Seligman, Sutton   +26 more
core   +2 more sources

Concrete Structure Inspired 3D‐Printed Framework Mechanically Reinforced Zwitterionic Hydrogel for Efficient Postoperative Abdominal Adhesion Prevention

Advanced Science, EarlyView.
Inspired by the establishment process and structure of concrete, a 3D‐printed PCL framework‐reinforced composite hydrogel is developed to overcome the mechanical limits of the original zwitterionic hydrogel toward clinic application of postoperative adhesion prevention.
Jianguo Song, Xin Cao, Ruirui Zhang, Shujie Cheng, Yi Wang   +4 more
wiley   +1 more source

Antihyperalgesic Effect of Buprenorphine Involves Nociceptin/Orphanin FQ Peptide–Receptor Activation in Rats With Spinal Nerve Injury–Induced Neuropathy

Journal of Pharmacological Sciences, 2013
.: We evaluated the effect of buprenorphine, a mixed agonist for μ-opioid receptors and nociceptin/orphanin FQ peptide (NOP) receptors, in neuropathic rats, using the paw pressure test. Buprenorphine, administered i.p. at 50, but not 20, μg/kg, exhibited
Tomoko Takahashi, Kazumasa Okubo, Shota Kojima, Hiroyuki Nishikawa, Motohide Takemura, Maho Tsubota-Matsunami, Fumiko Sekiguchi, Atsufumi Kawabata   +7 more
doaj   +1 more source

A Minimally Invasive Framework Reveals Region‐Specific Cerebrovascular Remodeling in Aging Using Intravital Functional Ultrasound Imaging and Ultrasound Localization Microscopy (fUS‐ULM)

Advanced Science, EarlyView.
A high‐resolution intravital imaging platform combining functional ultrasound and localization microscopy enables longitudinal, minimally invasive assessment of cerebrovascular function in aging studies. The present investigation reveals aging‐related reductions in neurovascular coupling, arteriole‐to‐venule ratio and vascular density, introducing a ...
Sharon Negri, Adam Nyul‐Toth, Madison Milan, Eva Troyano‐Rodriguez, Sherwin Tavakol, Jennifer Ihuoma, Zeke Reyff, Rakesh Rudraboina, Rafal Gulej, Raymond Jang, Anna Csiszar, Zoltan Ungvari, Audrey Cleuren, David R Miller, Andriy Yabluchanskiy, Mickael Tanter, Stefano Tarantini   +16 more
wiley   +1 more source

Evaluating the impact of a national naloxone programme on ambulance attendance at overdose incidents: a controlled time-series analysis [PDF]

, 2017
Background and Aims: It has been suggested that distributing naloxone to people who inject drugs (PWID) will lead to fewer attendances by emergency medical services at opioid-related overdose incidents if peer administration of naloxone was perceived ...
Ashworth, Becketti, Bennett, Bird, Box, Clark, Craig, Darke, Darke, Davoli, Jarosz, Knowlton, Lankenau, Lenton, Longo, McAuley, McAuley, McCain, Merchant, Merrall, Moore, Salmon, Seal, Shermann, Sporer, Strang, Walley, Weatherburn, World Health Organization (WHO), Wright   +29 more
core   +2 more sources

Microgel Aspect Ratio Influences Injectable Granular Hydrogel Scaffold Pore Structure and Cellular Invasion for Tissue Repair

Advanced Science, EarlyView.
Granular hydrogels are being developed for the repair of tissues, mostly with the use of spherical microgels. Here, injectable granular hydrogels formed from anisotropic particles (i.e., rod‐like) are explored to improve cellular invasion by increasing scaffold void volume fraction.
Gabriel J. Rodriguez‐Rivera, Siddharth Sharma, Chima V. Maduka, Sara Boyd, Amy R. Perry, Nikolas Di Caprio, Lindsay Riley, Connor E. Miksch, Daeyeon Lee, Tatiana Segura, David Issadore, Jason A. Burdick   +11 more
wiley   +1 more source