Results 141 to 150 of about 42,523 (291)

A new preclinical sheep model of medial meniscus anterior root repair. Part 2. Surgical strategy, technical considerations, pearls and pitfalls

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To address a gap in translational research by developing a preclinical sheep model of medial meniscus anterior root (MAR) repair in vivo and to compare probabilities of potential pitfalls and difficulties with humans. Methods Preoperative planning and surgical procedures applied to patients were adapted to adult sheep.
Matthias Brockmeyer   +4 more
wiley   +1 more source

Buprenorphine–naloxone [PDF]

open access: yesCanadian Medical Association Journal, 2018
Tina, Hu, Larry, Nijmeh, Adam, Pyle
openaire   +2 more sources

Landscape of informed consent practices and challenges in point‐of‐care clinical trials

open access: yesLearning Health Systems, EarlyView.
Abstract Point‐of‐care trials, an approach to trial design that assesses medical product effectiveness while fully integrating research and care, represent a promising opportunity to generate practically relevant evidence efficiently for priority disease areas.
Caleigh Propes   +2 more
wiley   +1 more source

Aligning forces to accelerate healthcare transformation: Insights from the UPMC learning community

open access: yesLearning Health Systems, EarlyView.
Abstract Introduction To accelerate transformation toward value‐based, equitable care, health systems need a viable approach for engaging and aligning multiple stakeholders to promote innovation. Building and sustaining learning communities offers one possible solution.
Diane Holder   +5 more
wiley   +1 more source

A learning health system model for addressing substance use: Denver Health Center for Addiction Medicine

open access: yesLearning Health Systems, EarlyView.
Abstract Introduction Substance use disorders (SUDs) continue to place heavy burdens on patients, health systems, and communities. Rapidly evolving treatment for SUDs requires health systems that can efficiently and effectively assess data and integrate evidence to practice.
Emily Bacon   +8 more
wiley   +1 more source

Antihyperalgesic Effect of Buprenorphine Involves Nociceptin/Orphanin FQ Peptide–Receptor Activation in Rats With Spinal Nerve Injury–Induced Neuropathy

open access: yesJournal of Pharmacological Sciences, 2013
.: We evaluated the effect of buprenorphine, a mixed agonist for μ-opioid receptors and nociceptin/orphanin FQ peptide (NOP) receptors, in neuropathic rats, using the paw pressure test. Buprenorphine, administered i.p. at 50, but not 20, μg/kg, exhibited
Tomoko Takahashi   +7 more
doaj  

A Background of the Opioid Epidemic and Its Relationship to the Medicaid Expansion [PDF]

open access: yes, 2019
Despite the recent increase in public awareness of the opioid epidemic, the background of this epidemic is still disappointingly unknown to the public.
Jang, Er Yearn
core   +2 more sources

Disentangling informing participants from obtaining their consent

open access: yesLearning Health Systems, EarlyView.
Abstract Introduction Pragmatic clinical trials conducted in the context of routine care frequently satisfy the regulatory criteria for a waiver of research consent. When they do, investigators and Institutional Review Boards might assume that there is no reason to communicate any information regarding the study to participants.
Patricia Pearl O'Rourke   +15 more
wiley   +1 more source

Administration of Long-Acting Injections [PDF]

open access: yes, 2018
Expanding the scope of pharmacy practice demonstrates that the profession has been successful at improving public health. Despite being a late adopter, New York\u27s limited experience with vaccines has improved immunization rates and lowered rates of ...
Noel, Christopher, Williams, Karl
core   +1 more source

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