Results 151 to 160 of about 43,211 (293)

Cross-sectional examination of characteristics of higher-dose buprenorphine prescriptions during the era of illicit fentanyl

open access: yesAddiction Science & Clinical Practice
Background In response to greater illicit fentanyl use, buprenorphine daily doses exceeding the FDA’s recommended target daily dose (16 mg) and maximum suggested daily dose (24 mg) may provide better outcomes, but little is known about higher dosage ...
Bradley D. Stein   +4 more
doaj   +1 more source

Identifying key risk factors for intentional self‐harm, including suicide, among a cohort of people prescribed opioid agonist treatment: A predictive modelling study

open access: yesAddiction, EarlyView.
Abstract Background and aims People with opioid use disorder are at increased risk of intentional self‐harm and suicide. Although risk factors are well known, most tools for identifying individuals at highest risk of these behaviours have limited clinical value.
Nicola R. Jones   +7 more
wiley   +1 more source

Ketamine-assisted buprenorphine initiation: a pilot case series

open access: yesAddiction Science & Clinical Practice
Background Many people with opioid use disorder who stand to benefit from buprenorphine treatment are unwilling to initiate it due to experience with or fear of both spontaneous and buprenorphine-precipitated opioid withdrawal (BPOW).
Lucinda A. Grande   +8 more
doaj   +1 more source

Pharmacological properties of buprenorphine, a new analgesic agent. Part II

open access: bronze, 1982
S Shintani   +11 more
openalex   +2 more sources

Extended‐release buprenorphine treatment for opioid use disorder: A mixed‐methods study of response and experience

open access: yesAddiction, EarlyView.
Abstract Background and aims An investigation of 24 weeks of extended‐release buprenorphine (BUP‐XR; Sublocade®) treatment for adults with opioid use disorder (OUD). Study aims were to characterise variations in clinical response, investigate personal factors influencing BUP‐XR experience and identify opportunities to tailor treatment interventions ...
Natalie Lowry   +13 more
wiley   +1 more source

Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor. [PDF]

open access: yes, 2018
The intrinsic efficacy of orthosteric ligands acting at G-protein-coupled receptors (GPCRs) reflects their ability to stabilize active receptor states (R*) and is a major determinant of their physiological effects.
Livingston, Kathryn E   +4 more
core  

Buprenorphine – an attractive opioid with underutilized potential in treatment of chronic pain

open access: yesJournal of Pain Research, 2015
Ish K Khanna, Sivaram PillarisettiNeuroPn Therapeutics, Alpharetta, GA, USAAbstract: Despite proven clinical utility, buprenorphine has not been used widely for the treatment of chronic pain.
Khanna IK, Pillarisetti S
doaj  

Among people who use heroin, tobacco smoking and illegal drugs cause a similar number of premature deaths

open access: yesAddiction, EarlyView.
Abstract Background and aims Most people who use heroin also smoke tobacco, but there is limited investment to reduce the prevalence of smoking in this group. This may be due to a perception that tobacco is less harmful than other substances and is a lower priority problem. Among people who use heroin in England, we aimed to compare tobacco smoking and
Dan Lewer   +2 more
wiley   +1 more source

Putting Families First: How the Opioid Epidemic is Affecting Children and Families, and the Child Welfare Policy Options to Address It [PDF]

open access: yes, 2019
: Opioids and Child Welfare Across the country, placements in foster care are rising. In 2016, the U.S. Department of Health and Human Services reported that 273,539 children in the U.S. entered foster care.
American Academy of Pediatrics Council on Foster Care, Adoption, and Kinship Care   +3 more
core   +1 more source

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