Results 151 to 160 of about 43,211 (293)
Background In response to greater illicit fentanyl use, buprenorphine daily doses exceeding the FDA’s recommended target daily dose (16 mg) and maximum suggested daily dose (24 mg) may provide better outcomes, but little is known about higher dosage ...
Bradley D. Stein+4 more
doaj +1 more source
Abstract Background and aims People with opioid use disorder are at increased risk of intentional self‐harm and suicide. Although risk factors are well known, most tools for identifying individuals at highest risk of these behaviours have limited clinical value.
Nicola R. Jones+7 more
wiley +1 more source
Ketamine-assisted buprenorphine initiation: a pilot case series
Background Many people with opioid use disorder who stand to benefit from buprenorphine treatment are unwilling to initiate it due to experience with or fear of both spontaneous and buprenorphine-precipitated opioid withdrawal (BPOW).
Lucinda A. Grande+8 more
doaj +1 more source
Pharmacological properties of buprenorphine, a new analgesic agent. Part II
S Shintani+11 more
openalex +2 more sources
The effects of buprenorphine, nalbuphine and butorphanol alone or following halothane anaesthesia on food and water consumption and locomotor movement in rats [PDF]
J. H. Liles, Paul Flecknell
openalex +1 more source
Abstract Background and aims An investigation of 24 weeks of extended‐release buprenorphine (BUP‐XR; Sublocade®) treatment for adults with opioid use disorder (OUD). Study aims were to characterise variations in clinical response, investigate personal factors influencing BUP‐XR experience and identify opportunities to tailor treatment interventions ...
Natalie Lowry+13 more
wiley +1 more source
Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor. [PDF]
The intrinsic efficacy of orthosteric ligands acting at G-protein-coupled receptors (GPCRs) reflects their ability to stabilize active receptor states (R*) and is a major determinant of their physiological effects.
Livingston, Kathryn E+4 more
core
Buprenorphine – an attractive opioid with underutilized potential in treatment of chronic pain
Ish K Khanna, Sivaram PillarisettiNeuroPn Therapeutics, Alpharetta, GA, USAAbstract: Despite proven clinical utility, buprenorphine has not been used widely for the treatment of chronic pain.
Khanna IK, Pillarisetti S
doaj
Abstract Background and aims Most people who use heroin also smoke tobacco, but there is limited investment to reduce the prevalence of smoking in this group. This may be due to a perception that tobacco is less harmful than other substances and is a lower priority problem. Among people who use heroin in England, we aimed to compare tobacco smoking and
Dan Lewer+2 more
wiley +1 more source
Putting Families First: How the Opioid Epidemic is Affecting Children and Families, and the Child Welfare Policy Options to Address It [PDF]
: Opioids and Child Welfare Across the country, placements in foster care are rising. In 2016, the U.S. Department of Health and Human Services reported that 273,539 children in the U.S. entered foster care.
American Academy of Pediatrics Council on Foster Care, Adoption, and Kinship Care+3 more
core +1 more source