Stereoselective method to quantify bupropion and its three major metabolites, hydroxybupropion, erythro-dihydrobupropion, and threo-dihydrobupropion using HPLC-MS/MS [PDF]
, 2016 Bupropion metabolites formed via oxidation and reduction exhibit pharmacological activity, but little is known regarding their stereoselective disposition.
Desta, Zeruesenay +3 more
core +1 more source
Bupropion administration increases resting-state functional connectivity in dorso-medial prefrontal cortex [PDF]
, 2017 Background: Patients on the selective serotonergic re-uptake inhibitors (SSRI) like citalopram report emotional blunting. We have shown previously that citalopram reduces resting-state functional connectivity (RSFC) in healthy volunteers in a number of ...
Dean, Zola +2 more
core +1 more source
The Efficacy and Toxicity of Bupropion in the Elderly [PDF]
, 2012 Bupropion is an antidepressant with excellent tolerability and few side effects or drug interactions. These characteristics suite it well for use both in the elderly and in the medically ill.
Howard, William T., M.D., M.S. +1 more
core +1 more source
Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones [PDF]
, 2017 Synthetic cathinones are a new class of psychostimulant substances. Rarely, they can cause liver injury but associated mechanisms are not completely elucidated.
Krähenbühl, Stephan +2 more
core +1 more source
, 2006 Individual change in behaviour has the potential to decrease the burden of chronic disease due to smoking, diet and low physical activity. Smoking quit rates can be increased by simple advice from a physician or trained counsellor, overall and in ...
Hillsdon, Melvyn +2 more
core +1 more source
Bupropion abuse and overdose [PDF]
Canadian Medical Association Journal, 2014 Bupropion is used widely as a smoking cessation aid and antidepressant and is available in immediate- and extended-release preparations. It blocks neuronal reuptake of dopamine and norepinephrine and antagonizes acetylcholine at neuronal nicotinic receptors.1 At therapeutic doses, bupropion ...
Nathan M. Stall +2 more
openaire +3 more sources
Effects of Administration of Perinatal Bupropion on the Population Spike Amplitude in Neonatal Rat Hippocampal Slice [PDF]
, 2010 Objective(s)Bupropion is an atypical antidepressant that is widely used in smoke cessation under FDA approval. The study of synaptic effects of bupropion can help to finding out its mechanism(s) for stopping nicotine dependence. In this study the effects
Firouz Ghaderi Pakdel +3 more
core
Impact of Scottish smoke-free legislation on smoking quit attempts and prevalence [PDF]
, 2011 <p><b>Objectives:</b> In Scotland, legislation was implemented in March 2006 prohibiting smoking in all wholly or partially enclosed public spaces. We investigated the impact on attempts to quit smoking and smoking prevalence.</p>
CM Fichtenberg +32 more
core +5 more sources
Protocol for the Smoking, Nicotine and Pregnancy (SNAP) trial: double-blind, placebo-randomised, controlled trial of nicotine replacement therapy in pregnancy [PDF]
, 2007 Background: Smoking in pregnancy remains a public health challenge. Nicotine replacement therapy (NRT) is effective for smoking cessation in non-pregnant people, but because women metabolise nicotine and cotinine much faster in pregnancy, it is unclear ...
A Charlton +39 more
core +5 more sources
Charcoal hemoperfusion in bupropion overdose
Journal of the Formosan Medical Association, 2014 Bupropion is a relatively new and popular medication for depression, with seizures as its major side effect. In the literature, there are insufficient data about hemodialysis following bupropion overdose. A 23-year-old female patient was brought to our emergency department with acute change in mental status and seizure after deliberate self-poisoning ...
Akdemir, Hizir Ufuk +5 more
openaire +5 more sources