Results 141 to 150 of about 37,026 (217)
Impulse: The Premier Undergraduate Neuroscience Journal, 2017 Cigarette smoking damages just about every organ in the body and reduces overall health. Even with the prevalence of accessible nicotine replacement therapies and behavioral counseling, there remains a need for alternative therapies to improve the odds ...
Adrian Paszek
doaj
Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions
Food Science &Nutrition, Volume 14, Issue 3, March 2026.Natural products such as EGCG, berberine, curcumin, and capsaicin modulate key metabolic pathways including AMPK activation, adipogenesis inhibition, and inflammatory signaling. While clinical trials demonstrate modest benefits on body weight and metabolic parameters, translational challenges related to bioavailability, dose feasibility, and regulatory
Ohoud M. Marie +1 more
wiley +1 more source
Addiction, Volume 121, Issue 3, Page 499-509, March 2026.Abstract Aims To assess whether combining nicotine replacement therapy (NRT) with varenicline improves long‐term smoking cessation rates compared with varenicline or NRT alone. Method Systematic review and meta‐analysis of randomized controlled trials (RCTs) or quasi‐RCTs, conducted according to PRISMA guidelines.
Xinmei Zhou +18 more
wiley +1 more source
The Response of Ventral Tegmental Area Dopaminergic Neurons to Bupropion: Excitation or Inhibition?
Basic and Clinical Neuroscience, 2019 Introduction: Antidepressants can modulate brain monoamines by acting on pre-synaptic and postsynaptic receptors. Autoreceptors can reduce the monoamines effect on the somatodendritic or pre-synaptic regions despite its postsynaptic counter effects.
Shirin Sadighparvar +4 more
doaj
Olanzapine Attenuates Cue-elicited Craving for Tobacco
, 2004 Rationale: Recent biological conceptualizations of craving and addiction have implicated mesolimbic dopamine activity as a central feature of the process of addiction. Imaging, and pharmacological studies have supported a role for dopaminergic structures
Hutchinson, Kent E +5 more
core
Clinical and Translational Science, Volume 19, Issue 3, March 2026.ABSTRACT Risperidone, an atypical antipsychotic, is increasingly prescribed in pediatric patients with psychiatric disorders. It is primarily metabolized by CYP2D6 to 9‐hydroxyrisperidone, an active metabolite associated with a higher risk of adverse effects.
Matthew H. Bennett +6 more
wiley +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 2403-2415, March 2026.Abstract Aims To assess the real‐world effectiveness of semaglutide versus tirzepatide in reducing major adverse cardiovascular events (MACE) among patients with overweight/obesity and established atherosclerotic cardiovascular disease (ASCVD) without diabetes in an insured US population.
Lauren Wilson +6 more
wiley +1 more source
European Journal of Neurology, Volume 33, Issue 3, March 2026.Multiple acyl‐coenzyme A dehydrogenase deficiency‐like disease has recently been described as a rare adverse effect of sertraline. We performed a nationwide population‐based retrospective study in Sweden (2014–2024) including 40 patients, corresponding to an incidence of 1.24 per 100,000 treated individuals per year.
Sofie Sunebo +9 more
wiley +1 more source
Psychogeriatrics, Volume 26, Issue 2, March 2026.ABSTRACT Background Apathy is a common symptom in degenerative diseases such as dementia. In this study, we developed the Japanese version of the brief Dimensional Apathy Scale (b‐J‐DAS), which requires caregivers to rate patient apathy using three apathy sub‐scales: executive, emotional and initiation.
Yuka Hirayama +3 more
wiley +1 more source
Dextromethorphan-bupropion combination in depression with dual diagnosis: Insights from a case series. [PDF]
Indian J PsychiatryAggarwal M +4 more
europepmc +1 more source