Results 71 to 80 of about 40,708 (270)

The Efficacy and Toxicity of Bupropion in the Elderly [PDF]

, 2012
Bupropion is an antidepressant with excellent tolerability and few side effects or drug interactions. These characteristics suite it well for use both in the elderly and in the medically ill.
Howard, William T., M.D., M.S., Warnock, Julia K., M.D., Ph.D.   +1 more
core   +1 more source

Efficacy of combined varenicline and nicotine replacement therapy compared with varenicline or nicotine replacement therapy alone for smoking cessation: A systematic review and meta‐analysis

Addiction, EarlyView.
Abstract Aims To assess whether combining nicotine replacement therapy (NRT) with varenicline improves long‐term smoking cessation rates compared with varenicline or NRT alone. Method Systematic review and meta‐analysis of randomized controlled trials (RCTs) or quasi‐RCTs, conducted according to PRISMA guidelines.
Xinmei Zhou, Zhenxiao Huang, Qingqing Song, Xin Xia, Anqi Cheng, Zhao Liu, Min Wang, Tingfen Ji, Ailifeire Aihemaiti, Ying Xie, Yi Liu, Yuxin Shi, Shunyi Shi, Yingman Gao, Hang Liu, Jiahui He, Liang Zhao, Dan Xiao, Chen Wang   +18 more
wiley   +1 more source

Varenicline for cannabis use disorder: A randomized controlled trial

Addiction, EarlyView.
Abstract Background and aims Although cannabis use is widespread and prevalence of cannabis use disorder (CUD) is increasing, limited advancements have been made in CUD medication development. The objective of this study was to test the efficacy of varenicline with medical management for reducing cannabis use in treatment‐seeking individuals with CUD ...
Aimee L. McRae‐Clark, Kevin M. Gray, Nathaniel L. Baker, Brian J. Sherman, Bryan Tolliver, Jessica Burt, Alonzo Steplight, Elizabeth Chapman, Amanda Wagner   +8 more
wiley   +1 more source

Effect of increasing intraperitoneal infusion rates on bupropion hydrochloride-induced seizures in mice

Annals of General Psychiatry, 2008
Background It is not known if there is a relationship between input rate and incidence of bupropion-induced seizures. This is important, since different controlled release formulations of bupropion release the active drug at different rates.
Fleming Rosanna, McMahon Louis, Williams Robert, Silverstone Peter H, Fogarty Siobhan   +4 more
doaj   +1 more source

Addiction‐related problems in Japan: A regional perspective

Addiction, EarlyView.
Abstract Japan's addiction landscape appears paradoxical. The lifetime use of illicit drugs is among the lowest in Organisation for Economic Cooperation and Development countries, but harm from alcohol, tobacco, and gambling ranks among the world's highest.
Soichiro Ide, Yoko Nishitani, Masahiko Sumitani, Masabumi Minami, Tadashi Isa, Masako Iseki, Michiko Ohkura, Hitoshi Okamoto, Tetsuro Kikuchi, Yuko Sekino, Hidehiko Takahashi, Kenji Takeuchi, Atsumi Nitta, Takeshi Honjo, Hiroshi Matsumoto, Tsuyoshi Miyakawa, Toshiya Murai, Toshihiko Matsumoto, Kazuyuki Nakagome, Kazutaka Ikeda   +19 more
wiley   +1 more source

The effectiveness, safety and cost-effectiveness of cytisine versus varenicline for smoking cessation in an Australian population: a study protocol for a randomized controlled non-inferiority trial [PDF]

, 2019
Smoking cessation medications are effective but often underutilised because of costs and side effects. Cytisine is a plant-based smoking cessation medication with over 50 years of use in Central and Eastern Europe.
Boland, Veronica C., Courtney, Ryan J., Doran, Christopher M., Farrell, Michael, Ferguson, Stuart G., Gartner, Coral, Hall, Wayne, Mattick, Richard P., McRobbie, Hayden, Mendelsohn, Colin P., Paul, Christine, Petrie, Dennis, Richmond, Robyn, Shakeshaft, Anthony, Siahpush, Mohammad, Thomas, Dennis, Tutka, Piotr, Walker, Natalie, West, Robert, Zwar, Nicholas   +19 more
core   +1 more source

Advances and Future Perspectives for the Management of Non‐Small Cell Lung Cancer in Australia: A Narrative Review

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Lung cancer remains Australia's leading cause of cancer death. With new screening and evolving therapies, equitable access and workforce readiness are essential. This review discusses current and emerging treatments for NSCLC in Australia, clinical trials underway, and future directions in delivering optimal, accessible care nationwide.
Lauren Julia Brown, Graham Meredith, Bo Gao, Pei Ding, Harriet Gee, Inês Pires da Silva, Adnan Nagrial, Eric Hau   +7 more
wiley   +1 more source

Smoking cessation in severe mental ill health : what works? an updated systematic review and meta-analysis [PDF]

, 2017
BACKGROUND: People with severe mental ill health are more likely to smoke than those in the general population. It is therefore important that effective smoking cessation strategies are used to help people with severe mental ill health to stop smoking ...
A Baker, A Baker, AE Evins, AE Evins, AE Evins, AE Evins, AH Weinberger, AL Baker, B O'Brien, BS Wu, C Bullen, C McDonald, E Ratschen, E Weiner, E Weiner, Emily Peckham, Garry Tew, GW Dalack, HK Chen, J Hartmann-Boyce, JM Williams, JM Williams, JM Williams, JW Tidey, KN Chengappa, KR Fontaine, L Banham, Liz Cook, ML Steinberg, ML Steinberg, Q Wu, RC Smith, RM Anthenelli, S Brown, S Fatemi, S Gilbody, Sally Brabyn, SE Adkison, Simon Gilbody, SM Gallagher, TP George, TP George, TP George, VC Wing   +43 more
core   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source