Results 31 to 40 of about 29,723 (221)

Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo

Scientific Reports, 2021
Burkholderia cenocepacia (B. cenocepacia) is an opportunistic bacterium; causing severe life threatening systemic infections in immunocompromised individuals including cystic fibrosis patients.
Shady Estfanous, Kathrin Krause, Midhun N. K. Anne, Mostafa Eltobgy, Kyle Caution, Arwa Abu Khweek, Kaitlin Hamilton, Asmaa Badr, Kylene Daily, Cierra Carafice, Daniel Baetzhold, Xiaoli Zhang, Tianliang Li, Haitao Wen, Mikhail A. Gavrilin, Hesham Haffez, Sameh Soror, Amal O. Amer   +17 more
doaj   +2 more sources

The cis-2-Dodecenoic Acid (BDSF) Quorum Sensing System in Burkholderia cenocepacia. [PDF]

Appl Environ Microbiol, 2022
It has been demonstrated that quorum sensing (QS) is widely employed by bacterial cells to coordinately regulate various group behaviors. Diffusible signal factor (DSF)-type signals have emerged as a growing family of conserved cell-cell communication ...
Wang M, Li X, Song S, Cui C, Zhang LH, Deng Y.   +5 more
europepmc   +2 more sources

Mutation of hmgA, encoding homogentisate 1,2-dioxygenase, is responsible for pyomelanin production but does not impact the virulence of Burkholderia cenocepacia in a chronic granulomatous disease mouse lung infection. [PDF]

Microbiol Spectr
The Burkholderia cepacia complex (Bcc) is a group of Gram-negative opportunistic bacteria often associated with fatal pulmonary infections in patients with impaired immunity, particularly those with cystic fibrosis (CF) and chronic granulomatous disease (
Moustafa DA, Wu L, Ivey M, Fankhauser SC, Goldberg JB.   +4 more
europepmc   +2 more sources

Genetic similarity of Burkholderia cenocepacia from cystic fibrosis patients

Brazilian Journal of Infectious Diseases, 2013
Burkholderia cenocepacia may cause serious infections in patients with cystic fibrosis, and this microorganism can be highly transmissible. Pulsed-field gel electrophoresis is widely used to study the dynamics of strain spread in cystic fibrosis patients.
Luana Pretto, Fernanda de-Paris, Alice Beatriz Mombach Pinheiro Machado, Andreza Francisco Martins, Afonso Luís Barth   +4 more
doaj   +6 more sources

The Small RNA ncS35 Regulates Growth in Burkholderia cenocepacia J2315 [PDF]

mSphere, 2018
Burkholderia cenocepacia J2315 is a member of the B. cepacia complex. It has a large genome with three replicons and one plasmid; 7,261 genes code for annotated proteins, while 113 code for functional RNAs. Small regulatory RNAs of B.
Sanne Kiekens, Andrea Sass, Filip Van Nieuwerburgh, Dieter Deforce, Tom Coenye   +4 more
doaj   +4 more sources

Unraveling Burkholderia cenocepacia H111 fitness determinants using two animal models [PDF]

mSystems
Burkholderia cenocepacia is an opportunistic pathogen that has been associated with nosocomial outbreaks in hospitals and can cause severe respiratory infections among immunocompromised patients and individuals suffering from cystic fibrosis.
Sarah Paszti, Stefano Gualdi, Marta Torres, Luis Augusto, Freya Harrison, Leo Eberl   +5 more
doaj   +2 more sources

The role of reactive oxygen species in antibiotic-induced cell death in Burkholderia cepacia complex bacteria [PDF]

, 2016
It was recently proposed that bactericidal antibiotics, besides through specific drug-target interactions, kill bacteria by a common mechanism involving the production of reactive oxygen species (ROS).
Acke, Marloes, Coenye, Tom, Cools, Freya, Cos, Paul, Gielis, Jan, Van Acker, Heleen   +5 more
core   +34 more sources

The late-stage steps of Burkholderia cenocepacia protein O-linked glycan biosynthesis are conditionally essential. [PDF]

J Biol Chem
Jebeli L, McDaniels TA, Ho DTT, Tahir H, Kai-Ming NL, Mcgaw M, Karlic KI, Lewis JM, Scott NE.   +8 more
europepmc   +2 more sources

Valdiazen Derivatives for Chemoproteomic Studies in Burkholderia cenocepacia H111

ChemBioChem, Volume 26, Issue 11, June 3, 2025.
Valdiazen is a quorum‐sensing signal isolated from B. c. H111. Using diazeniumdiolate chemical probes, several valdiazen‐binding proteins are identified, many of which are involved in structural and metabolic processes. This study offers valuable chemical tools and advances our understanding of the interactome associated with diazeniumdiolate signaling
Jiajun Ren, Anugraha Mathew, María Rodríguez‐García, Colin C. Regli, Olivier Blacque, Bernhard Spingler, Simon Sieber, Leo Eberl, Karl Gademann   +8 more
wiley   +4 more sources

Phylogeny, Synteny, and Distribution of Type III Secretion Systems in Burkholderia cenocepacia: A Closer Look Into Host Span. [PDF]

Microbiologyopen
T3SS is a dedicated machinery that mediates interactions between bacteria and eukaryotic cells, providing a functional interface in pathogenic or symbiotic associations. Phylogenetic analyses and T3SS‐gene synteny revealed nine gene clusters, with no needle protein gene (sctF). However, an orphan CDS encoding a putative SctF was found.
Cordeiro GT, de Oliveira HL, Mariano DCO, Torres YS, Dias GM, Neves BC.   +5 more
europepmc   +2 more sources