Results 61 to 70 of about 5,575 (204)

In silico analyses of penicillin binding proteins in Burkholderia pseudomallei uncovers SNPs with utility for phylogeography, species differentiation, and sequence typing.

PLoS Neglected Tropical Diseases, 2022
Burkholderia pseudomallei causes melioidosis. Sequence typing this pathogen can reveal geographical origin and uncover epidemiological associations. Here, we describe B.
Heather P McLaughlin, Christopher A Gulvik, David Sue   +2 more
doaj   +1 more source

PCR-RFLP based differentiation of Burkholderia mallei and Burkholderia pseudomallei

Molecular and Cellular Probes, 2004
Burkholderia mallei and Burkholderia pseudomallei manifest a high similarity with regard to clinical syndromes, glanders and melioidosis. Phenotypic and genotypic characters are also highly similar. In an attempt to differentiate the two organisms, the molecular method was applied. This study aimed to identify the different DNA fragment in B.
Suda, Tanpiboonsak, Atchara, Paemanee, Sasinee, Bunyarataphan, Sumalee, Tungpradabkul   +3 more
openaire   +2 more sources

Glanders: off to the races withBurkholderia mallei [PDF]

FEMS Microbiology Letters, 2007
Burkholderia mallei, the etiologic agent of the disease known as glanders, is primarily a disease affecting horses and is transmitted to humans by direct contact with infected animals. The use of B. mallei as a biological weapon has been reported and currently, there is no vaccine available for either humans or animals.
Gregory C, Whitlock, D Mark, Estes, Alfredo G, Torres   +2 more
openaire   +2 more sources

Intra‐ and Intermolecular Glycosylation of d‐Idopyranosyl and 6‐Deoxy‐d‐ido‐heptopyranosyl Donors: Toward the Repeating Unit of Campylobacter jejuni HS:4c Capsular Polysaccharide

European Journal of Organic Chemistry, Volume 29, Issue 4, January 26, 2026.
A comprehensive glycosylation study of diversely protected and activated d‐idopyranosyl and 6‐deoxy‐d‐ido‐heptopyranosyl donors using intra‐ and intermolecular coupling strategies is reported. Intramolecular aglycon delivery afforded 1,2‐cis‐β‐idopyranosides, while intermolecular glycosylation yielded chromatographically separable α‐ and β‐linked ...
Maude Cloutier, Nitish Verma, Ilona Douchez, Charles Gauthier   +3 more
wiley   +1 more source

Cross-Species Comparison of the Burkholderia pseudomallei, Burkholderia thailandensis, and Burkholderia mallei Quorum-Sensing Regulons [PDF]

Journal of Bacteriology, 2014
ABSTRACT Burkholderia pseudomallei , Burkholderia thailandensis , and Burkholderia mallei (the Bptm group) are close relatives with very different lifestyles: B.
Charlotte D, Majerczyk, Mitchell J, Brittnacher, Michael A, Jacobs, Christopher D, Armour, Matthew C, Radey, Richard, Bunt, Hillary S, Hayden, Ryland, Bydalek, E Peter, Greenberg   +8 more
openaire   +2 more sources

Burkholderia pseudomallei: animal models of infection.

, 2008
A range of animal models of Burkholderia pseudomallei infection have been reported, and the host species differ widely both in their susceptibility to infection and in the pathogenesis of disease.
Atkins, Tim, Bancroft, Gregory J, Cuccui, Jon, Easton, Anna, Haque, Ashraful, Harley, Vicki, Russell, Paul, Sarkar-Tyson, Mitali, Titball, Richard W, Wren, Brendan   +9 more
core   +1 more source

Plant-associated symbiotic Burkholderia species lack hallmark strategies required in mammalian pathogenesis [PDF]

, 2014
Burkholderia is a diverse and dynamic genus, containing pathogenic species as well as species that form complex interactions with plants. Pathogenic strains, such as B. pseudomallei and B.
Agapakis, Christina M, Angus, Annette A, Caballero-Mellado, Jesus, Dakora, Felix D, de Faria, Sergio M, Estrad-de los Santos, Paulina, Fong, Stephanie, Hirsch, Ann M, Kano, Stephanie, Song, Nannie, Weinstock, George, Yang, Paul, Yerrapragada, Shailaja   +12 more
core   +4 more sources

A gold nanoparticle-linked glycoconjugate vaccine against Burkholderia mallei [PDF]

Nanomedicine: Nanotechnology, Biology and Medicine, 2015
Burkholderia mallei are Gram-negative bacteria, responsible for the disease glanders. B. mallei has recently been classified as a Tier 1 agent owing to the fact that this bacterial species can be weaponised for aerosol release, has a high mortality rate and demonstrates multi-drug resistance.
Anthony E, Gregory, Barbara M, Judy, Omar, Qazi, Carla A, Blumentritt, Katherine A, Brown, Andrew M, Shaw, Alfredo G, Torres, Richard W, Titball   +7 more
openaire   +2 more sources

Type VI secretion: a beginner's guide [PDF]

, 2008
Type VI secretion is a newly described mechanism for protein transport across the cell envelope of Gram-negative bacteria. Components that have been partially characterised include an IcmF homologue, the ATPase ClpV, a regulatory FHA domain protein and ...
Akeda, Baron, Bladergroen, Brzuszkiewicz, Christopher M Bailey, Dandekar, Das, Das, de Bruin, Dreyfus, Dudley, Dudley, Durocher, Economou, Finn, Folkesson, Gardy, Henderson, Johnson, Kulasekara, Lewis EH Bingle, Mark J Pallen, Mougous, Mougous, Nano, Pallen, Parsons, Pukatzki, Pukatzki, Purcell, Roest, Schell, Schlieker, Seshadri, Shalom, Sheahan, Srinivasa Rao, Tatusov, VanRheenen, Ventre, Wang, Weibezahn, Williams, Yahr, Yeo, Zheng, Zheng, Zusman   +47 more
core   +1 more source

Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms

Drug Development Research, Volume 86, Issue 8, December 2025.
ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu, Maryam Ebunoluwa Zakariya, Abdulmuheez Abiola Abdulkareem, Olalekan Toheeb Okewale, Muhammad Halima Idris, Halimah Oluwayemisi Olayiwola   +5 more
wiley   +1 more source