Results 71 to 80 of about 5,430 (204)
Molecular Investigations of PenA-mediated β-lactam Resistance in Burkholderia pseudomallei [PDF]
, 2011 Burkholderia pseudomallei is the etiological agent of melioidosis. Because of the bacterium’s intrinsic resistance and propensity to establish latent infections, melioidosis therapy is complicated and prolonged. Newer generation b-lactams, specifically
Drew A Rholl +6 more
core +1 more source
Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms
Drug Development Research, Volume 86, Issue 8, December 2025.ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu +5 more
wiley +1 more source
Burkholderia mallei cellular interactions in a respiratory cell model [PDF]
Journal of Medical Microbiology, 2009 Burkholderia mallei is a facultative intracellular pathogen that survives and replicates in phagocytic cell lines. The bacterial burden recovered from naïve BALB/c mice infected by intranasal delivery indicated that B. mallei persists in the lower respiratory system. To address whether B.
Gregory C, Whitlock +5 more
openaire +2 more sources
Development of novel O-polysaccharide based glycoconjugates for immunization against glanders
Frontiers in Cellular and Infection Microbiology, 2012 Burkholderia mallei, the etiologic agent of glanders, causes severe disease in humans and animals and is a potential agent of biological warfare and terrorism. Diagnosis and treatment of glanders can be challenging, and in the absence of chemotherapeutic
Mary N Burtnick +4 more
doaj +1 more source
Frontiers in Microbiology, 2020 Burkholderia mallei and B. pseudomallei are highly pathogenic species which are closely related, but diverse regarding their prophage content. While temperate phages have not yet been isolated from B. mallei, several phages of B.
Jens A. Hammerl +5 more
doaj +1 more source
, 2004 This study reports the results of a collaborative study undertaken by two independent research groups to (a) confirm recent PCR-based detection of Yersinia pestis DNA in human teeth from medieval plague victims in France, and (b) to extend these ...
Cooper, Alan +6 more
core +1 more source
Comparison of the in vitro and in vivo susceptibilities of Burkholderia mallei to Ceftazidime and Levofloxacin [PDF]
, 2009 Background Burkholderia mallei is a zoonotic Gram negative bacterium which primarily infects solipeds but can cause lethal disease in humans if left untreated.
Barbara M Judy +3 more
core +2 more sources
مجله دانشگاه علوم پزشکی گرگان, 2016 Background and Objective: Iran remains a major stronghold for glanders in the Middle East. In Iran, the non-indigenous Burkholderia mallei Razi 325 strain is used in manufacturing of the mallein, required for malleination of animals. Multi Locus Variable
E Faraj Tabrizi +10 more
doaj
Iron Acquisition Mechanisms and Their Role in the Virulence of Burkholderia Species [PDF]
, 2017 Burkholderia is a genus within the β-Proteobacteriaceae that contains at least 90 validly named species which can be found in a diverse range of environments. A number of pathogenic species occur within the genus.
Butt, A.T., Thomas, M.S.
core +4 more sources
Genetic and phenotypic diversity in Burkholderia: contributions by prophage and phage-like elements [PDF]
, 2010 Background Burkholderia species exhibit enormous phenotypic diversity, ranging from the nonpathogenic, soil- and water-inhabiting Burkholderia thailandensis to the virulent, host-adapted mammalian pathogen B. mallei.
Catherine M Ronning +7 more
core +2 more sources