Results 11 to 20 of about 25,113 (239)

T6SS-5 and the cGAS-STING pathway in Burkholderia pseudomallei infection and immunity

Asian Pacific Journal of Tropical Biomedicine, 2023
Burkholderia pseudomallei is a causative agent of melioidosis that can infect humans and animals in endemic countries, specifically in Southeast Asia and tropical Australia. A fundamental component for the pathogenesis of Burkholderia pseudomallei is the
Noreafifah Semail, Nik Mohd Noor Nik Zuraina, Yasmin Khairani Muhammad Ismadi, Nurul Iman Mohamad, Azian Harun, Ismail Aziah, Zakuan Zainy Deris   +6 more
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Misidentification of Burkholderia pseudomallei, China [PDF]

Emerging Infectious Diseases, 2021
We report a case of melioidosis in China and offer a comparison of 5 commercial detection systems for Burkholderia pseudomallei. The organism was misidentified by the VITEK 2 Compact, Phoenix, VITEK mass spectrometry, and API 20NE systems but was eventually identified by the Bruker Biotyper system and 16S rRNA sequencing.
Bin Wu, Xinxin Tong, Haoyan He, Yinmei Yang, Huling Chen, Xiao Yang, Banglao Xu   +6 more
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The Burkholderia pseudomallei intracellular ‘TRANSITome’ [PDF]

Nature Communications, 2021
AbstractProkaryotic cell transcriptomics has been limited to mixed or sub-population dynamics and individual cells within heterogeneous populations, which has hampered further understanding of spatiotemporal and stage-specific processes of prokaryotic cells within complex environments.
Yun Heacock-Kang, Ian A. McMillan, Michael H. Norris, Zhenxin Sun, Jan Zarzycki-Siek, Andrew P. Bluhm, Darlene Cabanas, Robert E. Norton, Natkunam Ketheesan, Jeff F. Miller, Herbert P. Schweizer, Tung T. Hoang   +11 more
openaire   +3 more sources

Burkholderia pseudomallei and melioidosis

Nature Reviews Microbiology, 2023
Burkholderia pseudomallei, the causative agent of melioidosis, is found in soil and water of tropical and subtropical regions globally. Modelled estimates of the global burden predict that melioidosis remains vastly under-reported, and a call has been made for it to be recognized as a neglected tropical disease by the World Health Organization.
Ella M. Meumann, Direk Limmathurotsakul, Susanna J. Dunachie, Willem J. Wiersinga, Bart J. Currie   +4 more
openaire   +5 more sources

Detection and differentiation of Burkholderia species with pathogenic potential in environmental soil samples.

PLoS ONE, 2021
The Burkholderia pseudomallei phylogenetic cluster includes B. pseudomallei, B. mallei, B. thailandensis, B. oklahomensis, B. humptydooensis and B. singularis. Regarded as the only pathogenic members of this group, B. pseudomallei and B. mallei cause the
Sujintana Janesomboon, Veerachat Muangsombut, Varintip Srinon, Chatruthai Meethai, Chayada S Tharinjaroen, Premjit Amornchai, Patoo Withatanung, Narisara Chantratita, Mark Mayo, Vanaporn Wuthiekanun, Bart J Currie, Joanne M Stevens, Sunee Korbsrisate   +12 more
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Current Advances in Burkholderia Vaccines Development

Cells, 2020
The genus Burkholderia includes a wide range of Gram-negative bacterial species some of which are pathogenic to humans and other vertebrates. The most pathogenic species are Burkholderia mallei, Burkholderia pseudomallei, and the members of the ...
Guanbo Wang, Paulina Zarodkiewicz, Miguel A. Valvano   +2 more
doaj   +1 more source

A Quadruplex Real-Time PCR Assay for the Rapid Detection and Differentiation of the Most Relevant Members of the B. pseudomallei Complex: B. mallei, B. pseudomallei, and B. thailandensis. [PDF]

PLoS ONE, 2016
The Burkholderia pseudomallei complex classically consisted of B. mallei, B. pseudomallei, and B. thailandensis, but has now expanded to include B. oklahomensis, B. humptydooensis, and three unassigned Burkholderia clades.
Chinn-Woan Lowe, Benjamin A Satterfield, Daniel B Nelson, Joseph D Thiriot, Michael J Heder, Jordon K March, David S Drake, Cynthia S Lew, Annette J Bunnell, Emily S Moore, Kim L O'Neill, Richard A Robison   +11 more
doaj   +1 more source

Burkholderia pseudomallei Endophthalmitis [PDF]

Journal of Clinical Microbiology, 2007
ABSTRACT Melioidosis is an infectious disease caused by Burkholderia pseudomallei , a gram-negative bacillus. We report a case of endogenous endophthalmitis caused by B. pseudomallei that was treated with systemic and intravitreal ceftazidime.
Kuan-Jen, Chen, Ming-Hui, Sun, Chiun-Ho, Hou, Chi-Chin, Sun, Tun-Lu, Chen   +4 more
openaire   +2 more sources

Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump. [PDF]

, 2020
The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components.
Górecki, Kamil, McEvoy, Megan M
core   +2 more sources

A Unique Set of the Burkholderia Collagen-Like Proteins Provides Insight into Pathogenesis, Genome Evolution and Niche Adaptation, and Infection Detection. [PDF]

PLoS ONE, 2015
Burkholderia pseudomallei and Burkholderia mallei, classified as category B priority pathogens, are significant human and animal pathogens that are highly infectious and broad-spectrum antibiotic resistant.
Beth A Bachert, Soo J Choi, Anna K Snyder, Rita V M Rio, Brandon C Durney, Lisa A Holland, Kei Amemiya, Susan L Welkos, Joel A Bozue, Christopher K Cote, Rita Berisio, Slawomir Lukomski   +11 more
doaj   +1 more source