Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development. [PDF]
, 2014 UNLABELLED: Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infectious disease for which there is no vaccine. B. pseudomallei is listed as a tier 1 select agent, and as current therapeutic options are limited due to its ...
Atkins +34 more
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Recombinant Salmonella Expressing Burkholderia mallei LPS O Antigen Provides Protection in a Murine Model of Melioidosis and Glanders. [PDF]
PLoS ONE, 2015 Burkholderia pseudomallei and Burkholderia mallei are the etiologic agents of melioidosis and glanders, respectively. These bacteria are highly infectious via the respiratory route and can cause severe and often fatal diseases in humans and animals. Both
Dina A Moustafa +7 more
doaj +1 more source
Systemic melioidosis with prostatic abscess
Sri Lankan Journal of Infectious Diseases, 2023 Melioidosis is an infectious disease caused by the Gram-negative bacteria Burkholderia pseudomallei. The organism is a soil saprophyte and humans acquire infection via percutaneous inoculation through a breach in the skin.
F. S. Makeen +4 more
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PLoS Neglected Tropical Diseases, 2022 Burkholderia pseudomallei causes melioidosis. Sequence typing this pathogen can reveal geographical origin and uncover epidemiological associations. Here, we describe B.
Heather P McLaughlin +2 more
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An international, multicentre evaluation and description of Burkholderia pseudomallei infection in cystic fibrosis [PDF]
, 2015 BACKGROUND: Several cases of Burkholderia pseudomallei infection in CF have been previously reported. We aimed to identify all cases globally, risk factors for acquisition, clinical consequences, and optimal treatment strategies.
Bell, SC +3 more
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Development of Vaccines Against Burkholderia Pseudomallei [PDF]
Frontiers in Microbiology, 2011 Burkholderia pseudomallei is a Gram-negative bacterium which is the causative agent of melioidosis, a disease which carries a high mortality and morbidity rate in endemic areas of South East Asia and Northern Australia. At present there is no available human vaccine that protects against B.
Patel, N +5 more
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mBio, 2020 Burkholderia pseudomallei, the founding member of the B. pseudomallei complex (Bpc), is a biothreat agent and causes melioidosis, a disease whose treatment mainly relies on ceftazidime and meropenem. The concern is that B.
Nawarat Somprasong +7 more
doaj +1 more source
Journal of Clinical and Scientific Research, 2021 Melidiosis is a life-threatening infectious disease, and the causative organism is Burkholderia pseudomallei. It occurs as an environmental saprophyte in endemic regions of northern Australia and Southeast Asia.
Raju Iyengar +2 more
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Identification of small RNAs abundant in Burkholderia cenocepacia biofilms reveal putative regulators with a potential role in carbon and iron metabolism [PDF]
, 2017 Small RNAs play a regulatory role in many central metabolic processes of bacteria, as well as in developmental processes such as biofilm formation. Small RNAs of Burkholderia cenocepacia, an opportunistic pathogenic beta-proteobacterium, are to date not ...
Coenye, Tom +2 more
core +3 more sources
Effect of temperature on Burkholderia pseudomallei growth, proteomic changes, motility and resistance to stress environments. [PDF]
, 2018 Burkholderia pseudomallei is a flagellated, gram-negative environmental bacterium that causes melioidosis, a severe infectious disease of humans and animals in tropical areas. We hypothesised that B.
Chantratita, Narisara +5 more
core +1 more source