Results 31 to 40 of about 25,113 (239)

Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development. [PDF]

, 2014
UNLABELLED: Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infectious disease for which there is no vaccine. B. pseudomallei is listed as a tier 1 select agent, and as current therapeutic options are limited due to its ...
Atkins, Bakshi, Baugh, Chong, Cuccui, Dance, Davidson, Dong, Doublet, Eckert, Figurski, Freiberg, Gallagher, Haque, Holden, Hu, Kang, Karlyshev, Langmead, Langridge, Lewenza, Lynch, Nandi, Ortega, Sadosky, Sarkar-Tyson, Shalom, Sim, Thibault, Tumapa, van Opijnen, van Opijnen, Wiersinga, Yu, Zhang   +34 more
core   +3 more sources

Intracellular survival of Burkholderia pseudomallei [PDF]

Infection and Immunity, 1996
Burkholderia pseudomallei is the causative agent of melioidosis, a disease being increasingly recognized as an important cause of morbidity and mortality in many regions of the world. Several features of melioidosis suggest that B. pseudomallei is a facultative intracellular pathogen. This study was designed to assess the ability of B.
A L, Jones, T J, Beveridge, D E, Woods
openaire   +2 more sources

Autotransporters and their role in the virulence of Burkholderia pseudomallei and Burkholderia mallei.

Frontiers in Cellular and Infection Microbiology, 2011
Burkholderia pseudomallei and Burkholderia mallei are closely related Gram-negative bacteria responsible for the infectious diseases melioidosis and glanders, respectively.
Natalie eLazar Adler, Joanne eStevens, Mark eStevens, Edouard eGalyov   +3 more
doaj   +1 more source

Recombinant Salmonella Expressing Burkholderia mallei LPS O Antigen Provides Protection in a Murine Model of Melioidosis and Glanders. [PDF]

PLoS ONE, 2015
Burkholderia pseudomallei and Burkholderia mallei are the etiologic agents of melioidosis and glanders, respectively. These bacteria are highly infectious via the respiratory route and can cause severe and often fatal diseases in humans and animals. Both
Dina A Moustafa, Jennifer M Scarff, Preston P Garcia, Sara K B Cassidy, Antonio DiGiandomenico, David M Waag, Thomas J Inzana, Joanna B Goldberg   +7 more
doaj   +1 more source

Systemic melioidosis with prostatic abscess

Sri Lankan Journal of Infectious Diseases, 2023
Melioidosis is an infectious disease caused by the Gram-negative bacteria Burkholderia pseudomallei. The organism is a soil saprophyte and humans acquire infection via percutaneous inoculation through a breach in the skin.
F. S. Makeen, M. N. Pitagampola, S. Chandrasiri, S. Mendis, A. M. Abeygunasekera   +4 more
doaj   +1 more source

Prevalence and Identification of Burkholderia pseudomallei and Near-Neighbor Species in the Malabar Coastal Region of India.

PLoS Neglected Tropical Diseases, 2016
Accurate identification of pathogens with biowarfare importance requires detection tools that specifically differentiate them from near-neighbor species. Burkholderia pseudomallei, the causative agent of a fatal disease melioidosis, is one such biothreat
Bhavani V Peddayelachagiri, Soumya Paul, Sowmya Nagaraj, Madhurjya Gogoi, Murali H Sripathy, Harsh V Batra   +5 more
doaj   +1 more source

Melioidosis, Northeastern Brazil [PDF]

, 2005
Melioidosis is a fatal bacterial infection found in many parts of the tropical belt, particularly in Southeast Asia and northern Australia. Sporadic cases of the disease have been reported previously in Central and South America.
Rolim, D.B., Vilar, D.C.F.L., Sousa, A.Q., Miralles, I.S., de Oliveira, D.C.A., Harnett, G., O'Reilly, L., Howard, K., Sampson, I., Inglis, T.J.J.   +9 more
core   +2 more sources

Burkholderia ubonensis Meropenem Resistance: Insights into Distinct Properties of Class A β-Lactamases in Burkholderia cepacia Complex and Burkholderia pseudomallei Complex Bacteria

mBio, 2020
Burkholderia pseudomallei, the founding member of the B. pseudomallei complex (Bpc), is a biothreat agent and causes melioidosis, a disease whose treatment mainly relies on ceftazidime and meropenem. The concern is that B.
Nawarat Somprasong, Carina M. Hall, Jessica R. Webb, Jason W. Sahl, David M. Wagner, Paul Keim, Bart J. Currie, Herbert P. Schweizer   +7 more
doaj   +1 more source

In silico analyses of penicillin binding proteins in Burkholderia pseudomallei uncovers SNPs with utility for phylogeography, species differentiation, and sequence typing.

PLoS Neglected Tropical Diseases, 2022
Burkholderia pseudomallei causes melioidosis. Sequence typing this pathogen can reveal geographical origin and uncover epidemiological associations. Here, we describe B.
Heather P McLaughlin, Christopher A Gulvik, David Sue   +2 more
doaj   +1 more source

An international, multicentre evaluation and description of Burkholderia pseudomallei infection in cystic fibrosis [PDF]

, 2015
BACKGROUND: Several cases of Burkholderia pseudomallei infection in CF have been previously reported. We aimed to identify all cases globally, risk factors for acquisition, clinical consequences, and optimal treatment strategies.
Bell, SC, Currie, BJ, Geake, JB, Reid, DW   +3 more
core   +1 more source