Preserved and variable spatial‐chemical changes of lipids across tomato leaves in response to central vein wounding reveals potential origin of linolenic acid in signal transduction cascade [PDF]
Plant-Environment Interactions, 2021 Membrane lipids serve as substrates for the generation of numerous signaling lipids when plants are exposed to environmental stresses, and jasmonic acid, an oxidized product of 18‐carbon unsaturated fatty acids (e.g., linolenic acid), has been recognized
Dušan Veličković +13 more
doaj +3 more sources
Engineering transcriptional regulation of pentose metabolism in Rhodosporidium toruloides for improved conversion of xylose to bioproducts [PDF]
Microbial Cell Factories, 2023 Efficient conversion of pentose sugars remains a significant barrier to the replacement of petroleum-derived chemicals with plant biomass-derived bioproducts. While the oleaginous yeast Rhodosporidium toruloides (also known as Rhodotorula toruloides) has
Samuel T. Coradetti +11 more
doaj +2 more sources
mGem: Revisiting bacterial overflow metabolism [PDF]
mBioBacterial overflow metabolism, where cells perform oxidative fermentation despite the availability of ample oxygen and carbon sources, remains a long-standing paradox in microbial metabolism.
Niaz Bahar Chowdhury +3 more
doaj +2 more sources
A fast and sensitive size-exclusion chromatography method for plasma extracellular vesicle proteomic analysis. [PDF]
ProteomicsAbstract Extracellular vesicles (EVs) carry diverse biomolecules derived from their parental cells, making their components excellent biomarker candidates. However, purifying EVs is a major hurdle in biomarker discovery since current methods require large amounts of samples, are time‐consuming and typically have poor reproducibility. Here we describe a
Díaz Ludovico I +11 more
europepmc +2 more sources
Moisture modulates soil reservoirs of active DNA and RNA viruses [PDF]
Communications Biology, 2021 Wu et al. use a multi-omics approach (metagenomics, metatranscriptomics, and metaproteomics) to characterize soil viral responses to soil moisture.
Ruonan Wu +7 more
doaj +2 more sources
From Plants to Ants: Fungal Modification of Leaf Lipids for Nutrition and Communication in the Leaf-Cutter Ant Fungal Garden Ecosystem [PDF]
mSystems, 2021 Lipids are essential to all living organisms, as an energy source, as an important cellular structural component, and as a communication tool. In this study, we used global lipidomic methods to evaluate the lipids in leaf-cutter ant fungal gardens.
Lily Khadempour +9 more
doaj +4 more sources
Metabolic engineering to improve production of 3-hydroxypropionic acid from corn-stover hydrolysate in Aspergillus species [PDF]
Biotechnology for Biofuels and Bioproducts, 2023 Background Fuels and chemicals derived from non-fossil sources are needed to lessen human impacts on the environment while providing a healthy and growing economy.
Ziyu Dai +14 more
doaj +2 more sources
Computational tools and algorithms for ion mobility spectrometry-mass spectrometry. [PDF]
ProteomicsAbstract Ion mobility spectrometry‐mass spectrometry (IMS‐MS or IM‐MS) is a powerful analytical technique that combines the gas‐phase separation capabilities of IM with the identification and quantification capabilities of MS. IM‐MS can differentiate molecules with indistinguishable masses but different structures (e.g., isomers, isobars, molecular ...
Ross DH +5 more
europepmc +2 more sources
Prediction of non-intuitive metabolic targets with bayesian metabolic control analysis to improve 3-hydroxypropionic acid production in Aspergillus niger [PDF]
Frontiers in Bioengineering and BiotechnologyDevelopment of efficient bioconversion processes is limited by the ability to predictably improve metabolic flux. Here we deployed Bayesian Metabolic Control Analysis as a platform to integrate multi-omics data with metabolic modeling and evaluated its ...
Ziyu Dai +26 more
doaj +2 more sources
Immunization of pigs with replication-incompetent adenovirus-vectored African swine fever virus multi-antigens induced humoral immune responses but no protection following contact challenge [PDF]
Frontiers in Veterinary Science, 2023 IntroductionAfrican swine fever virus (ASFV) is a pathogen of great economic importance given that continues to threaten the pork industry worldwide, but there is no safe vaccine or treatment available.
Michelle D. Zajac +17 more
doaj +2 more sources