Results 111 to 120 of about 37,970 (217)

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

Promoting Treg Polarization‐Mediated Anti‐Scar and Appendage Regeneration in Wound Healing

Advanced Science, EarlyView.
This study develops a PLGA@LA‐BMP4‐PG bilayer scaffold to address scar formation and appendage loss in skin repair. The piezoelectric PLA layer enhances cell migration via electric fields, while GelMA delivers LA promoting Tregs polarization and BMP4 inhibiting FBs differentiation.
Yiwen Yang, Mingjie Kuang, Jiacheng Shi, Ruiyan Li, Yuhan Zhang, Xinting Liu, Runtan Li, Yong Kang, Bin Yao, Shuquan Zhang, Xiaoyuan Ji   +10 more
wiley   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Phagocyte NADPH Oxidase NOX2-Derived Reactive Oxygen Species in Antimicrobial Defense: Mechanisms, Regulation, and Therapeutic Potential-A Narrative Review. [PDF]

Antioxidants (Basel)
Țocu G, Ștefănescu BI, Stavăr Matei L, Țocu L.   +3 more
europepmc   +1 more source

Isolation and characterization of TayeBlu, a novel bacteriophage of <i>Azotobacter vinelandii</i>. [PDF]

Microbiol Spectr
Akanbi TM, Labat M, Sun T, Smith DA, Bagby SC.   +4 more
europepmc   +1 more source

Deep learning linking mechanistic models to single-cell transcriptomics data reveals transcriptional bursting in response to DNA damage. [PDF]

Elife
Huang Z, Luo S, Wang Z, Zhang Z, Jiang B, Nie Q, Zhang J.   +6 more
europepmc   +1 more source

A comprehensive analysis of the kinetics of infection of lytic bacteriophages specific to the ESKAPE and critical pathogens. [PDF]

World J Microbiol Biotechnol
Bajrak O, Cieślik M, Górski A, Jończyk-Matysiak E.   +3 more
europepmc   +1 more source

The first single-stranded DNA virus targeting Pectobacterium belongs to the family Microviridae and demonstrates a broad host range to Pectobacterium brasiliense soft rot pathogens. [PDF]

Arch Virol
Pedersen JS, Carstens AB, Rothgardt M, Viry A, Hille F, Franz CMAP, Kot W, Egorov A, Atkinson G, Hansen LH.   +9 more
europepmc   +1 more source

Genomic, Functional, and Evolutionary Insights into a Novel T7-like Phage B1 Infecting Multidrug-Resistant <i>Enterobacter cloacae</i>. [PDF]

Int J Mol Sci
Tsai YC, Teh SH, Huang P, Lin LC, Lin NT.   +4 more
europepmc   +1 more source

Parenterally administered pegbovigrastim alters leukocyte counts, granulocyte functions, and uterine cell population in healthy postpartum dairy cows. [PDF]

PLoS One
Dadarwal D, Crooks K, Lainetti P, Dickinson R, Ahmed KA, Palmer C.   +5 more
europepmc   +1 more source