Results 161 to 170 of about 25,232 (222)

Promoting donor microglial replacement through augmented conditioning or radiation sensitivity. [PDF]

Mol Ther
Lund TC, Durose W, Schindhelm E, Constans MM, Nolan EE, Gupta AO, Braaten K, Orchard PJ.   +7 more
europepmc   +1 more source

Single Intraperitoneal Busulfan Injection Induces Long-Term Reproductive Dysfunction and Reduces Male Offspring Ratio in BALB/c Mice. [PDF]

J Appl Toxicol
Pu R, Sun X, Zhang W, Ren X, Hua H, Long X, Wu Y, Cheng N.   +7 more
europepmc   +1 more source

Precision myeloablation with TDM-guided busulfan in pediatric primary immunodeficiencies: a real-world study of 28 patients. [PDF]

Transl Pediatr
Zhang K, Sun X, Yang J, Qin M, Zhu G, Jia C, Wang B, Wei A.   +7 more
europepmc   +1 more source

Clonal dynamics, tolerance, and adverse events after CD45-ADC-conditioned autologous HSPC transplantation in macaques. [PDF]

Blood Adv
Hayal TB, Abraham DM, Demirci S, Fan X, Zhou Y, Hyzy SL, Lin MI, Linde N, Engels T, Golomb J, Bonifacino A, Schifanella L, Hoffmann V, Brinster LR, Blair RV, Midkiff CC, Franchini G, Kaur A, Tisdale JF, Donahue RE, Hong SG, Wu C, Dunbar CE.   +22 more
europepmc   +1 more source

Altered Busulphan Exposure Associated with Concomitant Omeprazole during Hematopoietic Stem Cell Transplantation Conditioning: A Two-Case Report. [PDF]

Clin Drug Investig
El-Serafi I, He R, Zhao Y, Mattsson J, Hassan M.   +4 more
europepmc   +1 more source

Practical Guide for Managing Philadelphia-Negative Myeloproliferative Neoplasms in Patients with Organ Dysfunction.

Oncology
Abdulsalam S, Al-Shibly R, Kaddoura R, Ismail OM, Yassin MA.   +4 more
europepmc   +1 more source

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Inhibition of ferroptosis attenuates busulfan-induced oligospermia in mice

Toxicology, 2020
Busulfan is commonly used for cancer chemotherapy, nevertheless it cause male infertility via damaging the germ cells. Therefore, the underlying mechanism should be explored.
Fei Sun, Yinchuan Li
exaly   +2 more sources

The effect of granulocyte-colony stimulating factor, decitabine, and busulfan-cyclophosphamide versus busulfan-cyclophosphamide conditioning on relapse in patients with myelodysplastic syndrome or secondary acute myeloid leukaemia evolving from myelodysplastic syndrome undergoing allogeneic haematop

The Lancet Haematology, 2023
BACKGROUND Relapse remains high in patients with myelodysplastic syndrome-refractory anaemia with excess blasts (RAEB) or secondary acute myeloid leukaemia evolving from myelodysplastic syndrome undergoing allogeneic haematopoietic stem-cell ...
L. Xuan, M. Dai, E. Jiang, Yu Wang, Fen Huang, Zhi-Ping Fan, N. Xu, D. Nie, Xin-Quan Liang, Hong Chen, Jie-Yu Ye, Peng-Cheng Shi, Hui Liu, Hua Jin, R. Lin, Chen-Hua Yan, Yu Zhang, Jing Sun, Ming-Zhe Han, Qifa Liu   +19 more
semanticscholar   +1 more source

Individualizing busulfan dose in specific populations and evaluating the risk of pharmacokinetic drug-drug interactions

Expert Opinion on Drug Metabolism & Toxicology, 2023
Introduction Busulfan is an alkylating agent widely used in the conditioning of hematopoietic stem cell transplantation possessing a complex metabolism and a large interindividual and intra-individual variability, especially in children.
D. Combarel, J. Tran, J. Delahousse, G. Vassal, A. Paci   +4 more
semanticscholar   +1 more source

Leukemia after gene therapy for sickle cell disease: insertional mutagenesis, busulfan, both or neither.

Blood, 2021
Recently, encouraging data provided long-awaited hope for gene therapy as a cure for sickle cell disease (SCD). Nevertheless, the suspension of the bluebird bio gene therapy trial (ClinicalTrials.gov: NCT02140554) after participants developed acute ...
Rick Jones, M. DeBaun
semanticscholar   +1 more source