Results 51 to 60 of about 18,506 (177)

Stability of busulfan solutions in polypropylene syringes and infusion bags as determined with an original assay [PDF]

, 2021
Purpose The stability of busulfan solution in 0.9% sodium chloride and stored in polypropylene syringes or infusion bags was evaluated. Methods Busulfan solutions (0.54 mg/mL) were prepared and transferred to 50-mL polypropylene syringes and 100- and 500-
Fleury-Souverain, Sandrine, Rudaz, Serge, Bonnabry, Pascal, Guichard, Nicolas   +3 more
core  

Busulfan and subsequent malignancy: An evidence-based risk assessment.

, 2023
20.500.12530/87892The incidence of secondary malignancies associated with busulfan exposure is considered low, but has been poorly characterized. Because this alkylating agent is increasingly utilized as conditioning prior to gene therapy in nonmalignant
Long-Boyle, Janel R, Reatz, Meredith, Matos, Joana, Shah, Arpita, Sevilla, Julian, Booth, Claire, Spencer, Sueli Marques, Nicoletti, Eileen, Schwartz, Jonathan D, Kohn, Donald B, Shah, Ami J, López Lorenzo, José Luis   +11 more
core   +1 more source

Protective effect of curcumin on busulfan-induced renal toxicity in male rats

Renal Failure, 2020
Aim The aim of this study was to evaluate the effects of curcumin in an experimental model of busulfan-induced renal toxicity with emphasis on importance of histological alterations.
Mohammad-Amin Abdollahifar, Vahid Ebrahimi, Abbas Aliaghaei, Amir Raoofi, Amirreza Khosravi, Amirhosein Hasani, Ali Mehdizadeh, Mohammad Asadi   +7 more
doaj   +1 more source

The Effect of CoQ10 on Testicular Tissue in Rats Treating with Busulfan: Sperm Quality and Histological Changes. [PDF]

Iranian Journal of Veterinary Surgery, 2018
Objective: Busulfan(Bus) is a chemotherapy drug that is widely used for cancer treatment. The protective effect of CoQ10 evaluated on testis and sperm parameters after busulfan treatment.
Moones Moloody, Rasoul Shahrooz, Mazdak Razi, Leila Zarei, Vahid Mohammadi   +4 more
doaj   +1 more source

Association between the choice of the conditioning regimen and outcomes of allogeneic hematopoietic cell transplantation for myelofibrosis

Haematologica, 2023
Allogeneic hematopoietic cell transplantation (allo-HCT) remains the only curative treatment for myelofibrosis. However, the optimal conditioning regimen either with reduced-intensity conditioning (RIC) or myeloablative conditioning (MAC) is not well ...
Guru Subramanian Guru Murthy, Soyoung Kim, Noel Estrada-Merly, Muhammad Bilal Abid, Mahmoud Aljurf, Amer Assal, Talha Badar, Sherif M. Badawy, Karen Ballen, Amer Beitinjaneh, Jan Cerny, Saurabh Chhabra, Zachariah DeFilipp, Bhagirathbhai Dholaria, Miguel Angel Diaz Perez, Shatha Farhan, Cesar O. Freytes, Robert Peter Gale, Siddhartha Ganguly, Vikas Gupta, Michael R. Grunwald, Nada Hamad, Gerhard C. Hildebrandt, Yoshihiro Inamoto, Tania Jain, Omer Jamy, Mark Juckett, Matt Kalaycio, Maxwell M. Krem, Hillard M. Lazarus, Mark Litzow, Reinhold Munker, Hemant S. Murthy, Sunita Nathan, Taiga Nishihori, Guillermo Ortí, Sagar S. Patel, Marjolein van der Poel, David A. Rizzieri, Bipin N. Savani, Sachiko Seo, Melhem Solh, Leo F. Verdonck, Baldeep Wirk, Jean A. Yared, Ryotaro Nakamura, Betul Oran, Bart Scott, Wael Saber   +48 more
doaj   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Effects of Physalis angulata Leaf Extract on Female Reproductive Organs Following Busulfan Injection in Rats

Hayati Journal of Biosciences
Physalis angulata L. (ciplukan) is traditionally used as an herbal remedy with anticancer and antioxidant properties. At the same time, busulfan, a chemotherapy alkylating agent, causes gonadotoxicity and oxidative stress that impair female reproduction.
Aryani Satyaningtijas, Damiana Rita Ekastuti, Ronald Tarigan, Wahono Esthi Prasetyaningtyas, I Ketut Mudite Adnyane, Kusdiantoro Mohamad, Elsi Rahmadhani, Yanti Sulistyana, Arindina Mahendra   +8 more
doaj   +1 more source

Human placental mesenchymal stem cells ameliorate chemotherapy-induced damage in the testis by reducing apoptosis/oxidative stress and promoting autophagy

Stem Cell Research & Therapy, 2021
Background The side effects of busulfan on male reproduction are serious, so fertility preservation in children undergoing busulfan treatment is a major worldwide concern.
Jiafeng Lu, Zhenxing Liu, Mingkai Shu, Liya Zhang, Wenjuan Xia, Liuna Tang, Jincheng Li, Boxian Huang, Hong Li   +8 more
doaj   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Treosulfan is a safe and effective alternative to busulfan for conditioning in adult allogeneic HSCT patients: Data from a single center

Cancer Medicine
Introduction Type of conditioning regimen impacts the outcome of patients who undergo allogeneic HSCT since graft versus host disease (GVHD), infections, regimen related toxicities (RRT) are important causes of post‐transplant mortality.
Ant Uzay, Yasemin Gündoğdu, Barış Koşan, Tuğba Yetiş, S. Sami Kartı   +4 more
doaj   +1 more source