Results 151 to 160 of about 21,352 (197)

Increase of Activity of Tioconazole Against Resistant Microorganisms by the Addition of Butylated Hydroxyanisole

International Journal of Antimicrobial Agents, 2003
Tioconazole (TCZ) killed resistant Candida albicans in less than 3 min, after the addition of butylated hydroxyanisole (BHA), a phenolic antioxidant, at subinhibitory concentrations.
Giovanna Simonetti
exaly   +2 more sources

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Cytotoxicity of butylated hydroxyanisole in Vero cells

Cell Biology and Toxicology, 2006
Butylated hydroxyanisole (BHA) is perhaps the most extensively used synthetic antioxidant in the food and cosmetic industry, although considerable controversy exists in the literature regarding the safety of this compound. Most in vitro studies describing the effects of BHA have been performed in cancer cells, but it is unclear whether normal cells are
V, Labrador, P, Fernández Freire, J M, Pérez Martín, M J, Hazen   +3 more
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Histologic and autoradiographic studies on the forestomach of hamsters treated with 2-tert-butylated hydroxyanisole, 3-tert-butylated hydroxyanisole, crude butylated hydroxyanisole, or butylated hydroxytoluene.

Journal of the National Cancer Institute, 1986
The inductions of hyperplasia and neoplastic lesions in the forestomach of Syrian golden hamsters by 2-tert-butylated hydroxyanisole [(2-tert-BHA) CAS: 121-00-6], 3-tert-butylated hydroxyanisole [(3-tert-BHA) CAS: 88-32-4], crude butylated hydroxyanisole [(BHA) CAS: 25013-16-5], and butylated hydroxytoluene [(BHT) CAS: 128-37-0] were compared ...
M, Hirose, A, Masuda, Y, Kurata, E, Ikawa, Y, Mera, N, Ito   +5 more
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Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene

Journal of the American Oil Chemists' Society, 1975
AbstractButylated hydroxyanisole and butylated hydroxytoluene are used extensively as food antioxidants. It is estimated that man consumes ca. 0.1 mg/kg body wt daily of these antioxidants. At levels 500 times this level (50 mg/kg/day), both butylated hydroxyanisole and butylated hydroxytoluene appear to be free of any obviously injurious effects ...
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A new metabolite of butylated hydroxyanisole in man

Biopharmaceutics & Drug Disposition, 1983
AbstractButylated hydroxyanisole (I) is one of the most commonly used food antioxidants. Its use has been suggested to inhibit a variety of carcinogenic responses. The present study on the disposition kinetics of (I) in man indicates that contrary to previous reports, (I) undergoes significant O‐demethylation in the body yielding a tert‐butyl ...
R, El-Rashidy, S, Niazi
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Inhibition of the mono-oxygenase system by butylated hydroxyanisole and butylated hydroxytoluene

Life Sciences, 1974
Abstract The commonly used food-additive antioxidants, butylated hydroxyanisole and butylated hydroxytoluene, are inhibitors of the hepatic microsomal mono-oxygenase system, as assayed by benzpyrene hydroxylase activity and demethylase activities. Generally, butylated hydroxyanisole is a more potent inhibitor than butylated hydroxytoluene.
C S, Yang, F S, Strickhart, G K, Woo
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Cytotoxicity of butylated hydroxyanisole and butylated hydroxytoluene in isolated rat hepatocytes

Biochemical Pharmacology, 1988
The effects of the antioxidants butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) on isolated rat hepatocytes were investigated. Both antioxidants were observed to be cytotoxic in a concentration-dependent manner at concentrations ranging from 100 to 750 microM. At equimolar concentrations BHT was more cytotoxic than BHA. Their toxicity
D, Thompson, P, Moldéus
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The effect of butylated hydroxyanisole and butylated hydroxytoluene on behavioral development of mice

Developmental Psychobiology, 1974
AbstractThe chronic ingestion of .5% butylated hydroxyanisole (BHA) or butylated hydroxytoluene (BHT) by pregnant mice and their offspring resulted in a variety of behavioral changes. Compared to controls, BHA‐treated offspring showed increased exploration, decreased sleeping, decreased self‐grooming, slower learning, and a decreased orientation reflex.
J D, Stokes, C L, Scudder
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Cytotoxicity of butylated hydroxytoluene and butylated hydroxyanisole in cultured heart cells

Toxicology, 1978
Butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) at concentrations of 100 ppm (0.45 and 0.55 mM, respectively) produced a marked leakage of lactic dehydrogenase (LDH) from cultured myocardial and endotheloid cells into the culture medium. At this concentration both BHT and BHA markedly depressed the beating rate of cultured heart cells
S W, Leslie, S C, Gad, D, Acosta
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Epigenetic promoting effects of butylated hydroxyanisole

Food and Chemical Toxicology, 1986
Studies on the potential genotoxicity and epigenetic effects of BHA are reviewed. BHA was not DNA-reactive, but studies showed that it did have an effect on membrane systems, blocking exchange between hepatocytes and epithelial cells. The available data strongly suggest that BHA is an epigenetic carcinogen that produces forestomach neoplasms through a ...
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