Results 141 to 150 of about 20,742 (200)

Methemoglobin Formation from Butylated Hydroxyanisole and Oxyhemoglobin. Comparison with Butylated Hydroxytoluene and P-Hydroxyanisole

Free Radical Research Communications, 1992
The widely used food additives butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) react with oxyhemoglobin, thereby forming methemoglobin. The reaction rates were measured using visible spectroscopy, and second order rate constants were established for BHA and compared with p-hydroxyanisole.
Hans Nohl, H Nohl, Klaus Stolze
exaly   +3 more sources

A study of the teratogenicity of butylated hydroxyanisole on rabbits

Toxicology, 1978
A teratogenicity study on butylated hydroxyanisole (BHA) was carried out in SPF New Zealand White rabbits. BHA was given by gavage from day 7--18 of the gestation period in doses of 0, 50, 200 and 400 mg/kg body wt./day. The fetuses were removed on day 28.
E, Hansen, O, Meyer
openaire   +3 more sources

Interaction of butylated hydroxyanisole with mitochondrial oxidative phosphorylation

Biochemical Pharmacology, 1992
The antioxidant, butylated hydroxyanisole (BHA), has a number of effects on mitochondrial oxidative phosphorylation. In this study we apply the novel approach developed by Brand (Brand MD, Biochim Biophys Acta 1018: 128-133, 1990) to investigate the site of action of BHA on oxidative phosphorylation in rat liver mitochondria.
Fusi, Fabio, Sgaragli, G. P., Murphy, M. P.   +2 more
openaire   +4 more sources

Intake of butylated hydroxyanisole and butylated hydroxytoluene and stomach cancer risk: results from analyses in the Netherlands Cohort Study [PDF]

Food and Chemical Toxicology, 2000
Both carcinogenic and anticarcinogenic properties have been reported for the synthetic antioxidants butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT).
Hans Verhagen, Piet van den Brandt, R A Goldbohm   +2 more
exaly   +4 more sources

Monitoring of Butylated Hydroxyanisole in Food and Wastewater Samples Using Electroanalytical Two-Fold Amplified Sensor

Sustainability, 2022
A high performance and fast response sensor was fabricated as a monitoring system for the determination of butylated hydroxyanisole (BHA) in food and wastewater samples.
Sara Jafarian, Mohammad Ahmadi
exaly   +2 more sources

Butylated hydroxyanisole isomers induce distinct adipogenesis in 3T3-L1 cells

Journal of Hazardous Materials, 2019
Butylated hydroxyanisole (BHA) isomers, as the widely used anthropogenic antioxidants in food, have been revealed to induce endocrine disrupting effects, while the mechanism how BHA isomers regulate the lipogenic differentiation remains to be elucidated.
Jianqing Zhang, Guibin Jiang, Heidelore Fiedler   +2 more
exaly   +2 more sources

Bradykinin Inhibition by Butylated Hydroxyanisole

Science, 1970
Concentrations of butylated hydroxyanisole as low as 8 × 10 -9 mole per liter can inhibit detectably the contraction of smooth muscle elicited by bradykinin. The mechanism of the inhibitory effect of this food grade anti-oxidant is apparently complex, and the effect is only partially reversible.
L P, Posati, M J, Pallansch
openaire   +2 more sources

Comparative pharmacokinetics of butylated hydroxyanisole and butylated hydroxytoluene in rabbits

Journal of Pharmaceutical Sciences, 1980
The widespread use of butylated hydroxyanisole (I) and butylated hydroxytoluene (II) as food antioxidants recently has been criticized by the Food and Drug Administration because of their pharmacological and toxicological effects. Interest also has arisen recently in the use of these compounds as anticancer agents.
R, El-Rashidy, S, Niazi
openaire   +2 more sources

Histologic and autoradiographic studies on the forestomach of hamsters treated with 2-tert-butylated hydroxyanisole, 3-tert-butylated hydroxyanisole, crude butylated hydroxyanisole, or butylated hydroxytoluene.

Journal of the National Cancer Institute, 1986
The inductions of hyperplasia and neoplastic lesions in the forestomach of Syrian golden hamsters by 2-tert-butylated hydroxyanisole [(2-tert-BHA) CAS: 121-00-6], 3-tert-butylated hydroxyanisole [(3-tert-BHA) CAS: 88-32-4], crude butylated hydroxyanisole [(BHA) CAS: 25013-16-5], and butylated hydroxytoluene [(BHT) CAS: 128-37-0] were compared ...
M, Hirose, A, Masuda, Y, Kurata, E, Ikawa, Y, Mera, N, Ito   +5 more
openaire   +2 more sources

A new metabolite of butylated hydroxyanisole in man

Biopharmaceutics & Drug Disposition, 1983
AbstractButylated hydroxyanisole (I) is one of the most commonly used food antioxidants. Its use has been suggested to inhibit a variety of carcinogenic responses. The present study on the disposition kinetics of (I) in man indicates that contrary to previous reports, (I) undergoes significant O‐demethylation in the body yielding a tert‐butyl ...
R, El-Rashidy, S, Niazi
openaire   +2 more sources