Results 141 to 150 of about 21,352 (197)

Butylated Hydroxyanisole in Perspective

open access: yesChemico-Biological Interactions, 1991
Butylated hydroxyanisole (BHA) is a synthetic food antioxidant used to prevent oils, fats and shortenings from oxidative deterioration and rancidity. This review depicts the current knowledge on BHA. The physical and chemical characteristics of BHA are summarized and its function as a food antioxidant is made clear. The toxicological characteristics of
Hans Verhagen, J C Kleinjans
exaly   +5 more sources
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Methemoglobin Formation From Butylated Hydroxyanisole and Oxyhemoglobin. Comparison With Butylated Hydroxytoluene and P-Hydroxyanisole

Free Radical Research Communications, 1992
The widely used food additives butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) react with oxyhemoglobin, thereby forming methemoglobin. The reaction rates were measured using visible spectroscopy, and second order rate constants were established for BHA and compared with p-hydroxyanisole.
Hans Nohl, Klaus Stolze, H Nohl
exaly   +3 more sources

A study of the teratogenicity of butylated hydroxyanisole on rabbits

open access: yesToxicology, 1978
A teratogenicity study on butylated hydroxyanisole (BHA) was carried out in SPF New Zealand White rabbits. BHA was given by gavage from day 7--18 of the gestation period in doses of 0, 50, 200 and 400 mg/kg body wt./day. The fetuses were removed on day 28.
E, Hansen, O, Meyer
openaire   +3 more sources

Comparative Pharmacokinetics of Butylated Hydroxyanisole and Butylated Hydroxytoluene in Rabbits

Journal of Pharmaceutical Sciences, 1980
The widespread use of butylated hydroxyanisole (I) and butylated hydroxytoluene (II) as food antioxidants recently has been criticized by the Food and Drug Administration because of their pharmacological and toxicological effects. Interest also has arisen recently in the use of these compounds as anticancer agents.
Sarfaraz Khan Niazi
exaly   +3 more sources

Interaction of butylated hydroxyanisole with mitochondrial oxidative phosphorylation

open access: yesBiochemical Pharmacology, 1992
The antioxidant, butylated hydroxyanisole (BHA), has a number of effects on mitochondrial oxidative phosphorylation. In this study we apply the novel approach developed by Brand (Brand MD, Biochim Biophys Acta 1018: 128-133, 1990) to investigate the site of action of BHA on oxidative phosphorylation in rat liver mitochondria.
Fusi, Fabio   +2 more
openaire   +4 more sources

Antioxidant Synergism Between Butylated Hydroxyanisole and Butylated Hydroxytoluene

JAOCS, Journal of the American Oil Chemists' Society, 1995
AbstractDecay of the 2,6‐di‐tert‐butyl‐4‐methylphenoxy radical [butylated hydroxytoluene (BHT)‐radical] in the presence of butylated hydroxyanisole (BHA) was investigated in 1,2‐dimethoxyethane with or without triethylamine. BHT‐radical was conveniently generated by dissociation of its unstable dimer in solution.
Kanji Omura
exaly   +2 more sources

Intake of Butylated Hydroxyanisole and Butylated Hydroxytoluene and Stomach Cancer Risk: Results From Analyses in the Netherlands Cohort Study [PDF]

open access: yesFood and Chemical Toxicology, 2000
Both carcinogenic and anticarcinogenic properties have been reported for the synthetic antioxidants butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT).
Hans Verhagen   +2 more
exaly   +3 more sources

Butylated Hydroxyanisole Isomers Induce Distinct Adipogenesis in 3T3-L1 Cells

open access: yesJournal of Hazardous Materials, 2019
Butylated hydroxyanisole (BHA) isomers, as the widely used anthropogenic antioxidants in food, have been revealed to induce endocrine disrupting effects, while the mechanism how BHA isomers regulate the lipogenic differentiation remains to be elucidated.
Jianqing Zhang   +2 more
exaly   +2 more sources

Bradykinin Inhibition by Butylated Hydroxyanisole

Science, 1970
Concentrations of butylated hydroxyanisole as low as 8 × 10 -9 mole per liter can inhibit detectably the contraction of smooth muscle elicited by bradykinin. The mechanism of the inhibitory effect of this food grade anti-oxidant is apparently complex, and the effect is only partially reversible.
L P, Posati, M J, Pallansch
openaire   +2 more sources

Effects of butylated hydroxyanisole in Drosophila melanogaster

Mutation Research/Genetic Toxicology, 1976
The standard sex-linked recessive lethal test using "Basc" virgin females and treated Canton S males was used to test potential mutagenicity of ingested butylated hydroxyanisole (BHA) on mature spermatozoa. Ethyl methanesulfonate (EMS) was employed as a positive control and at lower concentrations a roughly linear dose response curve resulted.
M P, Miyagi, C R, Goodheart
openaire   +2 more sources

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