Results 171 to 180 of about 174,283 (288)

The evolving role of regulatory T cells in Sjögren's disease pathogenesis and the promise of Treg‐based therapies: A comprehensive review

Rheumatology &Autoimmunity, EarlyView.
Graphical Abstract The evolving role of regulatory T cells in primary Sjögren's disease pathogenesis and the promise of Treg‐based therapies. Abstract Sjögren's disease (SjD) is a chronic systemic autoimmune disorder characterised by exocrine gland dysfunction and diverse systemic manifestations.
Gagan Urs, Bharath Raj Srinivasan, Himabindu Jayaprakash Narayan, Mirunalini Gobinath, Lekitha Manjunath, Mahabaleshwar Mamadapur   +5 more
wiley   +1 more source

The role of <i>Clostridium butyricum</i> and its metabolites in modulating gut mucosal immunity: implications for viral infections and inflammatory diseases. [PDF]

Front Immunol
Qian S, Li S, Ye K, Lu S, Sha X, Zhang D, Xu Z, Song X, Li R.   +8 more
europepmc   +1 more source

Inulin‐Butyrate Nanogel for Modulation of Gut Microbiome, Intestinal Barrier, and Regulatory T‐Cells in Colitis

Small, EarlyView.
ABSTRACT Inflammatory bowel diseases (IBD) arise from a vicious cycle of intestinal barrier dysfunction, gut microbiome dysbiosis, and dysregulated immune responses. Current therapies predominantly suppress immunity but fail to address root causes or break this cycle.
Nayoon Park, Bom Lee, Hyeon‐Jeong Jeon, Ji Yeon Kim, Suyeon Park, Seong‐Eun Kim, Dong‐Kyu Lee, Yonghyun Lee   +7 more
wiley   +1 more source

SMILE: Extraction‐free submicron‐resolution mapping of lipid chain length and unsaturation by stimulated Raman imaging

VIEW, EarlyView.
In this work, we develop submicron‐resolution mapping of intracellular lipid elements (SMILE) as an extraction‐free vibrational spectroscopic imaging platform based on hyperspectral stimulated Raman scattering microscopy with a spectral analysis pipeline for pixel‐resolved lipid profiling.
Yihui Zhou, Xiangjie Huang, Xingxin Liu, Ling Zhang, Jie Huang, Jing Zhao, Yongqing Zhang, Jin Zhang, Yanqing Gong, Delong Zhang, Hyeon Jeong Lee   +10 more
wiley   +1 more source

2'-Fucosyllactose and its metabolites propionate/butyrate suppress inflammation through a shared TLR4/p38 MAPK-dependent pathway <i>in vitro</i> and <i>in vivo</i>. [PDF]

Curr Res Food Sci
Na K, Chao C, Yu T, Wang L, Liu X, Zhang L, Feng K, Lei J, Xiong Y, Guo X.   +9 more
europepmc   +1 more source

Phylosymbiosis and Parallel Geographical Patterns in the Gut Microbiota of Desert‐Dwelling Amphibians and Reptiles

Integrative Zoology, EarlyView.
Host species emerge as a significant contributor to interspecies variations in the gut microbiota of desert‐dwelling amphibians and reptiles, illustrating phylosymbiosis among the studied species. Geographical factors partially account for interpopulation variations in the gut microbiota of Bufotes pewzowi and Teratoscincus przewalskii, with parallel ...
Wei Zhu, Liming Chang, Chunlin Zhao, Bo Cai, Lulu Sui, Cheng Shen, Hanqi Li, Bin Wang, Jianping Jiang   +8 more
wiley   +1 more source

Short-Chain Fatty Acids Elicit Differential Expression of Growth Factors and Pro-Inflammatory Cytokines in Immortalized Rat Enteric Glial Cells. [PDF]

Nutrients
Beltran MM, Defries DM.
europepmc   +1 more source

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

Integrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source

The effect of adding colostrum or sodium butyrate to the diet on the intestinal barrier of weaned piglets. [PDF]

PLoS One
Pieszka M, Szczepanik K, Kubica P, Oczkowicz M, Orczewska-Dudek S, Śliwiński B, Gala Ł.   +6 more
europepmc   +1 more source

Effect of Social Rank on Gut Microbes and Their Metabolites of Greater Long‐Tailed Hamsters (Tscherskia triton)

Integrative Zoology, EarlyView.
Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley   +1 more source