Results 201 to 210 of about 174,283 (288)

Gut microbial metabolite butyrate boosts p53-expressing telomerase-specific oncolytic adenovirus efficacy by enhancing infectivity and activating MHC-I/cGAS-STING. [PDF]

Cancer Immunol Immunother
Sakamoto M, Kuroda S, Katayama T, Mikane Y, Hanzawa S, Kadowaki D, Yoshida Y, Hamada Y, Sugimoto R, Yagi C, Hashimoto M, Kanaya N, Kakiuchi Y, Kikuchi S, Shigeyasu K, Tazawa H, Kagawa S, Urata Y, Fujiwara T.   +18 more
europepmc   +1 more source

Antibiotic Exposure in Early Life and Risk of Type 1 Diabetes: A Meta‐Analysis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Early‐life antibiotic use may increase the risk of childhood type 1 diabetes (T1D), potentially through gut microbiota dysbiosis and associated effects on immune development. This meta‐analysis evaluated associations between early‐life antibiotic use and T1D.
Sharan Ram, Marine Corbin, Andrea ’t Mannetje, Jeroen Douwes, Amanda Kvalsvig, Amanda Eng   +5 more
wiley   +1 more source

Targeting microbiome-driven epigenetic modifications: a new frontier in breast cancer treatment. [PDF]

Clin Epigenetics
Bai Y, Kong X, Wang J.
europepmc   +1 more source

Two Metschnikowia nectar yeast species have similar volatile profiles but elicit differential foraging in bee pollinators

Ecological Entomology, EarlyView.
Yeasts that specialize in flower nectar play an important role in pollination ecology. Metschnikowia reukaufii and Metschnikowia koreensis were the most prevalent nectar yeasts found in our field sites. Bee pollinators exhibited different behavioural responses to nectar yeasts in field experiments. Bees visited more flowers with M.
M. Elizabeth Moore, Lindsey Wilson, Nathan Brandt, Ayako Wada‐Katsumata, Ahmed M. Saveer, Coby Schal, Robert R. Dunn, Rebecca E. Irwin, Caiti Smukowski Heil   +8 more
wiley   +1 more source

Metabolic crosstalk between oral microbiota and the host in OSCC: emerging roles of microbial metabolites in tumor initiation and progression. [PDF]

Front Cell Infect Microbiol
Wu Y, Han B, Zhang B, Li J, Ren B, Su Z.
europepmc   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

Microbiota-derived short-chain fatty acids in hematopoietic stem cell transplantation: immunomodulation at the host-microbiota interface. [PDF]

Front Microbiol
Hajjar C, Kuijper EJ, Butel MJ, Khoury G, Mallah M, Karam Sarkis D, Lesnik P, Le Goff W, Bazarbachi A, Abifadel M.   +9 more
europepmc   +1 more source

Intrinsic specificity of a ‘core’ TIP60 acetyltransferase complex in Drosophila

The FEBS Journal, EarlyView.
The intrinsic substrate selectivity of the Drosophila TIP60‐core acetyltransferase was determined using synthetic nucleosome arrays. Targeted mass spectrometry revealed site‐specific acetylation of histones H2A, H2A.V, and H4, uncovering distinct acetylation rates and patterns across individual lysines.
Silke Krause, Marco Borsò, Marisa Müller, Axel Imhof, Zivkos Apostolou, Peter B. Becker   +5 more
wiley   +1 more source

<i>Clostridium butyricum</i> alleviates multiple myeloma by remodeling the bone marrow microenvironment and inhibiting PI3K/AKT pathway through the gut‒bone axis. [PDF]

Gut Microbes
Wang J, Zi F, Liu W, Liu C, Zhang Z, Kong L, Xu X, Wei J, Chen T, Li J.   +9 more
europepmc   +1 more source