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Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2022
ALSUntangled reviews alternative and off-label treatments for people living with amyotrophic lateral sclerosis (PALS). Here we review butyrate and its different chemical forms (butyrates). Butyrates have plausible mechanisms for slowing ALS progression and positive pre-clinical studies.
Yuyao Sun +19 more
openaire +2 more sources
ALSUntangled reviews alternative and off-label treatments for people living with amyotrophic lateral sclerosis (PALS). Here we review butyrate and its different chemical forms (butyrates). Butyrates have plausible mechanisms for slowing ALS progression and positive pre-clinical studies.
Yuyao Sun +19 more
openaire +2 more sources
Nondigestible carbohydrates, butyrate, and butyrate-producing bacteria
Critical Reviews in Food Science and Nutrition, 2018Nondigestible carbohydrates (NDCs) are fermentation substrates in the colon after escaping digestion in the upper gastrointestinal tract. Among NDCs, resistant starch is not hydrolyzed by pancreatic amylases but can be degraded by enzymes produced by large intestinal bacteria, including clostridia, bacteroides, and bifidobacteria.
Xiaodan, Fu +4 more
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Current Opinion in Clinical Nutrition and Metabolic Care, 2012
Butyrate is physiologically produced by the microbial fermentation of dietary fibers and plays a plurifunctional role in intestinal cells. This review examines the recent findings regarding the role and mechanisms by which butyrate regulates intestinal metabolism and discusses how these findings could improve the treatment of several gastrointestinal ...
Alda J, Leonel +1 more
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Butyrate is physiologically produced by the microbial fermentation of dietary fibers and plays a plurifunctional role in intestinal cells. This review examines the recent findings regarding the role and mechanisms by which butyrate regulates intestinal metabolism and discusses how these findings could improve the treatment of several gastrointestinal ...
Alda J, Leonel +1 more
openaire +2 more sources
Annals of the New York Academy of Sciences, 1998
Abstract: The aims of this study were to ascertain tolerability, safety and efficacy of oral isobutyramide (150 mg/kg bw/day) in stimulating fetal hemoglobin production in twelve thalassemia intermedia patients. Patients were treated for 28 days and followed for a further 28 days.
M D, Cappellini +6 more
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Abstract: The aims of this study were to ascertain tolerability, safety and efficacy of oral isobutyramide (150 mg/kg bw/day) in stimulating fetal hemoglobin production in twelve thalassemia intermedia patients. Patients were treated for 28 days and followed for a further 28 days.
M D, Cappellini +6 more
openaire +2 more sources
Butyrate and Colorectal Cancer: The Role of Butyrate Transport
Current Drug Metabolism, 2013Colorectal cancer (CRC) is one of the most common solid tumors worldwide. A diet rich in dietary fiber is associated with a reduction in its risk. Butyrate (BT) is one of the main end products of anaerobic bacterial fermentation of dietary fiber in the human colon.
Pedro, Gonçalves, Fátima, Martel
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