Light-Induced On-Surface Reactions: Bridging Photochemistry and Surface Science. [PDF]
ChempluschemThis minireview examines molecular on‐surface photochemistry as an emerging strategy for synthesizing carbon‐based nanomaterials on substrates. A special emphasis is placed on bridging traditional photochemistry principles with surface science concepts.
Frezza F +3 more
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Repurposing Neurological Drugs Against Dengue Virus Infection. [PDF]
J Trop MedDengue fever is highly prevalent in tropical and subtropical regions, where it is caused by dengue virus (DENV) and transmitted by arthropods. While DENV infection manifests with a spectrum of clinical symptoms, severe cases can lead to hemorrhagic fever and shock syndrome.
Jhan MK, Shen TJ, Nguyen TT, Lin CF.
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Acute cardiovascular effects associated with the use of prescription medications: A Danish nationwide screening study. [PDF]
Br J Clin PharmacolAbstract Aim This study aims to conduct a hypothesis‐generating screening for acute cardiovascular effects of prescription medications. Methods This Danish nationwide screening study was conducted among incident cases of cardiovascular diseases, including myocardial infarction (MI), ischemic stroke (IS), heart failure (HF), venous thromboembolism (VTE),
Abbasi SH +4 more
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Usability of the Japanese Late-Stage Elderly Questionnaire for screening major depression. [PDF]
PsychogeriatricsAbstract Background Older adults with major depression are at risk of frailty and long‐term care needs. Consequently, screening for major depression is imperative to prevent such risks. In Japan, the Late‐Stage Elderly Questionnaire was developed to evaluate older adults' holistic health, including mental well‐being.
Sato S +3 more
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Scandium-Catalyzed Highly Selective Deoxygenation of Alcohols by Using Hydrosilanes as Reductants. [PDF]
ChemistryA new protocol for selective C─O bond cleavage using Sc(OTf)₃ as the catalyst in the presence of hydrosilanes as reductants is reported. Alcohols, ketones, and alkyl halides were efficiently reduced to the corresponding alkanes, with excellent regio‐ and chemoselectivity.
Buhaibeh R +5 more
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Systematic review and meta-analysis of antipsychotic discontinuation in dementia. [PDF]
Alzheimers Dement (N Y)Abstract INTRODUCTION Antipsychotics are used to treat behavioral and psychological symptoms of dementia (BPSD). However, treatment is associated with adverse outcomes. A 2018 Cochrane review found low‐quality evidence that discontinuation may have little effect on BPSD by primarily comparing the difference in number of study non‐completers between ...
Roche S +5 more
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A molecular basis for selective antagonist destabilization of dopamine D3 receptor quaternary organization [PDF]
, 2017 The dopamine D3 receptor (D3R) is a molecular target for both first-generation and several recently-developed antipsychotic agents. Following stable expression of this mEGFP-tagged receptor, Spatial Intensity Distribution Analysis indicated that a ...
Caltabiano, Gianluigi +6 more
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Reduction or discontinuation of antipsychotics for challenging behaviour in adults with intellectual disability: a systematic review [PDF]
, 2017 The use of antipsychotics to manage challenging behaviour in adults with intellectual disability is widespread but controversial, and evidence is scarce.
Hassiotis, A, Sheehan, R
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Acute transaminitis after initial days of starting haloperidol. [PDF]
, 2019 Haloperidol is a first-generation antipsychotic butyrophenone that is lipophilic, readily absorbed, and extensively metabolized in the liver. The occurrence of elevated liver enzymes with haloperidol is reported to be 2.4% with cases generally occurring ...
Bota, Robert +3 more
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In situ generation of Mes2Mg as a non-nucleophilic carbon-centred base reagent for the efficient one-pot conversion of ketones to silyl enol ethers [PDF]
, 2008 Treatment of commercially available MesMgBr with 1,4-dioxane produces the key Mes2Mg reagent in situ which then mediates the deprotonation of ketones to deliver trimethylsilyl enol ethers, at readily accessible temperatures and without any nucleophilic ...
Hayes, Douglas. +2 more
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