One-pot oximation–Beckmann rearrangement of ketones and aldehydes to amides of industrial interest: Acetanilide, caprolactam and acetaminophen [PDF]
High yielding one-pot oximation–Beckmann rearrangement of ketones to amides in ktrifluoroacetic acid has been conducted on several ketones and aldehydes. The substrate reactivity showed to depend on both oximation and Beckmann rearrangement reaction rate.
Arico', Fabio +5 more
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Proper Use of Ketamine and Innovar [PDF]
Definitions of ketamine and innovar along with corresponding indications, contraindications, techniques for administration, complications, and treatment of ...
Corssen, Guenter
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Stereoselective ketone rearrangements with hypervalent iodine reagents [PDF]
The first stereoselective version of an iodine(III)-mediated rearrangement of arylketones in the presence of orthoesters is described. The reaction products, α-arylated esters, are very useful intermediates in the synthesis of bioactive compounds such as
Adams +76 more
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Potent and selective chemical probe of hypoxic signaling downstream of HIF-α hydroxylation via VHL inhibition [PDF]
Chemical strategies to using small molecules to stimulate hypoxia inducible factors (HIFs) activity and trigger a hypoxic response under normoxic conditions, such as iron chelators and inhibitors of prolyl hydroxylase domain (PHD) enzymes, have broad ...
A Melvin +78 more
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Special Article: One Resident\u27s Perspective on a Different Style of Psychopharmacological Practice [PDF]
This article provides a comparison of psychopharmacological practices in the U.S. and France. The prescription as well as proscription of various classes of psychotropic drugs are considered.
Amiel, M.D., Michael +1 more
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Identifikasi Permasalahan Dosis Dan Interaksi Obat Pada Pasien Askes Dan Umum Penderita Epilepsi Di RSUD Prof. Dr. Margono Soekardjo Purwokerto [PDF]
Epilepsy is one of common illness that occurs in society, not only in the matter of medical side but also social and economy to the patients or family.
Listiana, S. A. (Siska) +2 more
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Treatment of Acute Neuroleptic‐Induced Movement Disorders [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90365/1/j.1875-9114.1994.tb02851.x ...
Guthrie, Sally K., Tonda, Margaret E.
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Neuroleptanalgesia for acute abdominal pain: a systematic review [PDF]
Background: Acute abdominal pain (AAP) comprises up to 10% of all emergency department (ED) visits. Current pain management practice is moving toward multi-modal analgesia regimens that decrease opioid use.
Bigalli, Alberto A Castro +7 more
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Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis [PDF]
Malaria and cryptosporidiosis, caused by apicomplexan parasites, remain major drivers of global child mortality. New drugs for the treatment of malaria and cryptosporidiosis, in particular, are of high priority; however, there are few chemically ...
Alan H. Fairlamb +84 more
core +7 more sources
Implied in a title such as this one is an obligation to determine the present state of the art, or science, if you will, and to elucidate, in a manner of speaking, where we are, why we are, and in which direction we may be going.
Stephen, C. Ronald
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