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An improved method for butyrylcholinesterase phenotyping
Biochemical Genetics, 1994An improved method for the identification of butyrylcholinesterase phenotypes is proposed. It is based on modifications of a method that uses alpha-naphthyl acetate as substrate and DL-propranolol and Ro2-0683 as inhibitors. The proposed modifications make the method more rapid and increase the accuracy of the determinations of the phenotypes tested ...
G, Picheth +4 more
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Production of the Butyrylcholinesterase Knockout Mouse
Journal of Molecular Neuroscience, 2006The butyrylcholinesterase (BChE [EC 3.1.1.8]) knockout mouse is a model for BChE deficiency in humans. The existence of genetic variants of human BChE was discovered after a new muscle relaxant, succinylcholine, was introduced into the practice of medicine in the late 1950s.
Bin, Li +3 more
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Thermal inactivation of butyrylcholinesterase and acetylcholinesterase
Journal of Protein Chemistry, 1993Differences were observed in the extent of thermal inactivation of human butyrylcholinesterase (BuChE) and eel acetylcholinesterase (AChE). BuChE was more resistant to 57 degrees C inactivation than was AChE. Thermal inactivation of BuChE was reversible and followed first-order kinetics.
S K, Burgess, S L, Oxendine
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Ionisation of horse serum butyrylcholinesterase
Biochimica et Biophysica Acta (BBA) - Enzymology, 1970Abstract The effect of pH on horse serum cholinesterase (acylcholine acyl-hydrolase, EC 3.1.1.8) catalyzed o- nitrophenyl butyrate hydrolysis shows a non-competitive type of inhibition. The K m value is independent of the pH of the medium, and may be regarded as the true dissociation constant of the ES complex. Its value varies only
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Some radiometric microassays for butyrylcholinesterase
Analytical Biochemistry, 1978Abstract A simple method for purifying [ 14 C]butyrylcholine and incubation conditions suitable for estimating butyrylcholinesterase activity are described. Solvent extraction and anion- and cation-exchange procedures for separating butyrylcholine from butyric acid are described and compared.
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Butyrylcholinesterase: A Multifaceted Pharmacological Target and Tool
Current Protein and Peptide Science, 2020Keng Yoon Yeong
exaly
Serum Butyrylcholinesterase Activity in Leprosy
International Journal of Leprosy and Other Mycobacterial Diseases, 2004Lavanya M, Suneetha +5 more
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Butyrylcholinesterase deficiency and its clinical importance in anaesthesia: a systematic review
Anaesthesia, 2019Kim Wildgaard
exaly