Results 161 to 170 of about 205,619 (384)

Mechanisms governing bystander activation of T cells

open access: yesFrontiers in Immunology
The immune system is endowed with the capacity to distinguish between self and non-self, so-called immune tolerance or “consciousness of the immune system.” This type of awareness is designed to achieve host protection by eliminating cells expressing a ...
Mohammed Yosri   +5 more
doaj   +1 more source

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt   +2 more
wiley   +1 more source

983 The Role of Bystander Effects in the Anti-tumour Activity of the Hypoxia-activated Prodrug PR-104a

open access: bronze, 2012
Annika Foehrenbacher   +4 more
openalex   +1 more source

Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei   +7 more
wiley   +1 more source

Power-law Null Model for Bystander Mutations in Cancer [PDF]

open access: gold, 2014
Loes M. Olde Loohuis   +2 more
openalex   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

open access: yesMed Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li   +8 more
wiley   +1 more source

Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

open access: yesImmunity, 1998
K. Murali-Krishna   +7 more
semanticscholar   +1 more source

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