Results 61 to 70 of about 86,809 (257)

From Public Access Defibrillator to Personal Access Defibrillator: Proposal of Prompts to Optimize Automated External Defibrillation Use by Laypeople

Eurasian Journal of Emergency Medicine
Aim: This study aimed to assess whether integrating additional prompts to the automated external defibrillator (AED) interface could reduce common errors among untrained laypeople.
Cristian Abelairas-Gómez, Aida Carballo-Fazanes, Clara Painceira-Díaz, Carmen García-Rodríguez, Antonio Rodríguez-Núñez   +4 more
doaj   +1 more source

Engineered Transformer Base Editor with Enhanced Editing Efficiency

Advanced Science, EarlyView.
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen, Letong Liang, Rui Xu, Tianyi Wang, Hongyan Chen, Daru Lu   +5 more
wiley   +1 more source

Bystander intervention in emergencies: diffusion of responsibility

, 1968
BYSTANDER INTERVENTION IN EMERGENCIES: DIFFUSION OF RESPONSIBILITY Bystander intervention in emergencies: diffusion of responsibility (-
Latané, Bibb, Darley, John M.
core   +1 more source

“That’s Not Sexual Harassment, Is It?”: How Understandings of Sexual Harassment Impact Intervention Work

Tidsskrift for Kjønnsforskning
Sexual harassment (SH) is commonly categorized into gender harassment, unwanted sexual attention, and sexual coercion, and can be understood as part of a broader continuum of violence often experienced by women. To better understand why SH persists, this
Brita Bjørkelo, Malin Wieslander, Ulla-Carin Hedin, Linda Lane, Kristian Stampe Nielsen, Anniken Grønstad, Eva Gemzøe Mikkelsen   +6 more
doaj   +1 more source

The use of virtual reality in the study of people's responses to violent incidents

Frontiers in Behavioral Neuroscience, 2009
This paper reviews experimental methods for the study of the responses of people to violence in digital media, and in particular considers the issues of internal validity on the one hand and ecological validity or generalisability of results to events in
Aitor Rovira, David Swapp, Bernhard Spanlang, Bernhard Spanlang, Mel Slater, Mel Slater, Mel Slater   +6 more
doaj   +1 more source

Bystander effect and perpetrator’s gender: an experimental study on sexual harrasment on men

, 2023
openNonostante negli ultimi anni si stia dedicando maggiore attenzione al tema della violenza sessuale, le molestie nei confronti degli uomini rimangono materia ancora scarsamente trattata ed insufficientemente discussa.
ROSA, MARIA VITTORIA
core  

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

Relationship between NAFLD and coronary artery disease: A Mendelian randomization study

Hepatology, EarlyView., 2022
Abstract Background and Aims There is an ongoing debate on whether NAFLD is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the present study was to assess the causal relationship between NAFLD and CAD.
Zhewen Ren, Pomme I. H. G. Simons, Anke Wesselius, Coen D. A. Stehouwer, Martijn C. G. J. Brouwers   +4 more
wiley   +1 more source

Childhood unpredictability, expressive suppression, and mindfulness as predictors of bystanders' outsider behaviors in cyberbullying among Chinese undergraduates: a moderated mediation model

Frontiers in Psychology
BackgroundBystanders' outsider behaviors play a vital role in the development and persistence of cyberbullying incidents, a prevalent form of harmful digital engagement.
Rui Chen, Rui Chen, Rui Chen, Dan Ming, Ting Zhou, Xin Hao, Cui-ying Fan   +6 more
doaj   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source