Results 71 to 80 of about 86,809 (257)
GMS Journal for Medical EducationObjective: The aim of this study was to analyze the potential benefits of real-time feedback in resuscitation training for participants in the prehospital emergency chain and to compare differences in the quality of chest compressions (CC) with and ...
Stella-Karolin Krispin +4 more
doaj +1 more source
Demonstration of bystander affiliation and solicited bystander affiliation in ravens.
, 2013 Frequency distributions of latency to first affiliative post-conflict interaction directed from a bystander to the conflict victim (A) and directed from the victim to a bystander (B) in post-conflict periods (PCs; filled circles) and matched control ...
Orlaith N. Fraser (179718) +1 more
core +1 more source
CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome
Advanced Science, EarlyView.By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen +11 more
wiley +1 more source
The Recognition of Bystander Recovery [PDF]
, 1974 The Recognition Of Bystander ...
Greenwood, Clarence
core
SAT1‐Induced Spermidine Depletion Potentiates Food Allergy
Advanced Science, EarlyView.Spermidine depletion, driven by upregulated spermidine/spermine N1‐acetyltransferase (SAT1), potentiates food allergy by promoting mast cell degranulation through autophagy suppression. SAT1 physically interacts with the long noncoding RNA Cdk19os to inhibit Atg5 and Atg7, disrupting autophagic flux.
Manman Liu +8 more
wiley +1 more source
SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer
Advanced Science, EarlyView.Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian +8 more
wiley +1 more source
Advanced Science, EarlyView.This Review outlines the biological framework of entry, maintenance, and awakening in dormant minimal residual disease across gynecologic cancers. By mapping critical biological dependencies—from metabolic plasticity to microenvironment interactions—it evaluates novel interception concepts and presents a translational framework combining single‐cell ...
Shih‐Hsuan Cheng +7 more
wiley +1 more source
HIV-1 Induced Bystander Apoptosis
Viruses, 2012 Apoptosis of uninfected bystander cells is a key element of HIV pathogenesis and believed to be the driving force behind the selective depletion of CD4+ T cells leading to immunodeficiency.
Anjali Joshi +2 more
doaj +1 more source
Advanced Science, EarlyView.A dual‐transmembrane Bicephali CAR‐T platform simultaneously targets CD276 and NKG2D ligands to address antigen heterogeneity in non‐small cell lung cancer. By improving immune synapse formation, mitochondrial fitness, antioxidant capacity, and stem‐like persistence, this design enhances durable tumor control and provides a versatile strategy to ...
Lina Wang +8 more
wiley +1 more source
Irradiated tumor cells affect the growth of bystander tumor cells.
, 2016 Irradiated tumor cells mixed with bystander tumor cells were injected in mice. The tumor growth was monitored by tumor volume measurements (A) and images of representative mouse from each group are shown (B).
Pritha Ray (279482) +8 more
core +1 more source