Results 101 to 110 of about 213,956 (190)

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

Cáncer Bucal [PDF]

, 2008
El Cáncer bucal y bucofaríngeo representa el 3% de todos los canceres, sin embargo, son de los que menor tasa de sobre vida a 5 años presentan. Los canceres bucales son diagnosticados en estadios avanzados en un 68-72% de los casos, lo cual en muchas ...
Alemán Navas, Ramón Manuel, Martinez Mendoza, Maria Guadalupe, Sandoval, Luis   +2 more
core  

Modelado de esferoides de cáncer de colon con modelos basados en agentes.

, 2023
En el ranking de cánceres más frecuentes, el cáncer colorrectal (CCR) aparece ocupando el tercer puesto y suponiendo el 10.7 % de los nuevos casos. Es la cuarta causa más común de muerte relacionada con el cáncer en el mundo. Los métodos in silico tienen gran potencial e importancia en el estudio del cáncer.
Orga Nebra, Paula, Doblaré Castellano, Manuel, Arroyo Vázquez, Raquel Beatriz   +2 more
openaire   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

TRATAMIENTO QUIRURGICO DEL CÁNCER DE TIROIDES: 2014-2016 Experiencia en el Centro Médico ``LIC. ADOLFO LÓPEZ MATEOS´´ [PDF]

, 2017
RESUMEN OBJETIVOS: Analizar los resultados obtenidos del tratamiento quirúrgico del cáncer de la glándula tiroides durante el perdido comprendido entre 2014-2016.
Dolores Velázquez, Rigoberto, GAONA VALLE, LAURA SORAYA, SÁNCHEZ HERNÁNDEZ, EDVINO   +2 more
core  

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Factores predictores de sobrevida en pacientes con alguna patologia cancerosa maediante análisis de regresión de cox caso: próstata [PDF]

, 2009
El presente trabajo investigativo desarrolla el Análisis de Sobrevida para los pacientes con Cáncer de Próstata de la Sociedad de Lucha Contra el Cáncer(SOLCA).
Martinez Mayorga, Robin, Ramirez Figueroa, John   +1 more
core   +1 more source

Análisis de las características clínicas y resultados de cirugía en pacientes con cáncer colorrectal en un hospital de tercer nivel en México tras regular la atención hospitalaria por la emergencia sanitaria de COVID-19

Revista de Cirugía Colorrectal
Objetivo: El cáncer colorrectal (CCR) figura como la tercera neoplasia más frecuente a nivel mundial. Sin embargo, la atención médica de esta enfermedad se vio interrumpida durante la pandemia de COVID-19, lo que ocasionó retrasos en el diagnóstico y tratamiento del CCR.
Abelardo Juanz-González, Samanta K. Dosal-Limón, Alejandro Vela-Torres, Billy Jiménez-Bobadilla, Juan A. Villanueva-Herrero, Gerardo J. Maya-Vacío, Ana J. Iberri-Jaime, Jorge L. De León-Rendón   +7 more
openaire   +2 more sources

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source