Results 51 to 60 of about 555,429 (217)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Editorial

Revista Guatemalteca de Urología, 2020
En este volumen tenemos artículos como el de revisión realizado por los doctores Flores–Carbajal y Medrano–Urtecho, quienes logran repasar y actualizar los aspectos más importantes de la Nefrectomía Parcial especialmente en el abordaje Laparoscópico ...
Hugo Roberto Arriaga Morales
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Renal pelvic urothelial carcinoma with imaging features presenting as renal infarction 1 case report and literature review

Urology Case Reports
Renal pelvic cancer is relatively rare in clinical practice, and renal pelvic cancer characterized by renal infarction is even rarer. We here report a case of renal pelvic urothelial carcinoma with squamous metaplasia with renal infarction as the main ...
Haidong Yang, Wenli Yang, Nanjun Duan, Jing Luo, Zhengyan Yang, Weiran Zhang, Wei Feng, Haifeng Wang   +7 more
doaj   +1 more source

Bilateral Renal Tumour as Indicator for Birt-Hogg-Dubé Syndrome

Case Reports in Medicine, 2014
Birt-Hogg-Dubé (BHD) syndrome is a cancer disorder caused by a pathogenic FLCN mutation characterized by fibrofolliculomas, lung cysts, pneumothorax, benign renal cyst, and renal cell carcinoma (RCC).
P. C. Johannesma, R. J. A. van Moorselaar, S. Horenblas, L. E. van der Kolk, E. Thunnissen, J. H. T. M. van Waesberghe, F. H. Menko, P. E. Postmus   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A framework to distinguish healthy/cancer renal CT images using the fused deep features. [PDF]

Front Public Health, 2023
Rajinikanth V, Vincent PMDR, Srinivasan K, Ananth Prabhu G, Chang CY.   +4 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Cáncer de pelvis renal: cuadro clínico-patológico y sobrevida

Revista Médica Herediana, 1998
Objetivo: Identificar el cuadro clínico-patológico y determinar la influencia del estadío clínico, tipo histológico y tipo de tratamiento en la sobrevida a 5 años.
Juan Diaz Plasencia, Lucio Sanchez Ferrer-Valle, Guillermo Rodriguez Mantilla, William Calipuy Abanto, Gonzalo Rodriguez Espejo, Freddy Rojas Martinez   +5 more
doaj